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ChemicalBook >> CAS DataBase List >> 4-AMINO-1,8-NAPHTHALIMIDE

4-AMINO-1,8-NAPHTHALIMIDE

4-AMINO-1,8-NAPHTHALIMIDE price.
  • $44 - $1022.42
  • Product name: 4-AMINO-1,8-NAPHTHALIMIDE
  • CAS: 1742-95-6
  • MF: C12H8N2O2
  • MW: 212.2
  • EINECS:217-110-1
  • MDL Number:MFCD00006921
  • Synonyms:4-Amino-1,8-naphthalenedicarbimide;4-Amino-1,8-naphthalenedicarboximide;4-Aminonaphthalene-1,8-dicarbimide;6-Amino-2,3-dihydro-1H-benzo[de]isoquinoline-1,3-dione;6-Amino-2H-benzo[de]isoquinoline-1,3-dione;4-Amino-1,8-naphthalimide,98%;6-amino-1h-benz(de)isoquinoline-3(2h)-dione ;6-amino-1h-benz[de]isoquinoline-3(2h)-dione
Price19 Properties Safety Information Description
19 prices
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Brand
  • AK Scientific
  • Alfa Aesar
  • Alichem
  • American Custom Chemicals Corporation
  • Biosynth Carbosynth
  • Cayman Chemical
  • Crysdot
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
Package
  • 5mg
  • 10mg
  • 20MG
  • 50mg
  • 100mg
  • 250mg
  • 500mg
  • 1g
  • 2g
  • 5g
  • 10g
  • ManufacturerAK Scientific
  • Product number2616AL
  • Product description4-Amino-1,8-naphthalimide
  • Packaging250mg
  • Price$127
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ64358
  • Product description4-Amino-1,8-naphthalimide, 95%
  • Packaging100mg
  • Price$48.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ64358
  • Product description4-Amino-1,8-naphthalimide, 95%
  • Packaging1g
  • Price$201.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlichem
  • Product number1742956
  • Product description6-Amino-1H-benzo[de]isoquinoline-1,3(2H)-dione
  • Packaging10g
  • Price$1022.42
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number1742956
  • Product description6-Amino-1H-benzo[de]isoquinoline-1,3(2H)-dione
  • Packaging5g
  • Price$925.41
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0011463
  • Product description4-AMINO-1,8-NAPHTHALIMIDE 95.00%
  • Packaging20MG
  • Price$618.73
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA67151
  • Product description4-Amino-1,8-naphthalimide
  • Packaging250mg
  • Price$57.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA67151
  • Product description4-Amino-1,8-naphthalimide
  • Packaging500mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA67151
  • Product description4-Amino-1,8-naphthalimide
  • Packaging1g
  • Price$140
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA67151
  • Product description4-Amino-1,8-naphthalimide
  • Packaging2g
  • Price$254
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA67151
  • Product description4-Amino-1,8-naphthalimide
  • Packaging5G
  • Price$550
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number18509
  • Product description4-amino-1,8-Naphthalimide ≥95%
  • Packaging10mg
  • Price$44
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18509
  • Product description4-amino-1,8-Naphthalimide ≥95%
  • Packaging50mg
  • Price$193
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18509
  • Product description4-amino-1,8-Naphthalimide ≥95%
  • Packaging100mg
  • Price$341
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18509
  • Product description4-amino-1,8-Naphthalimide ≥95%
  • Packaging250mg
  • Price$745
  • Updated2024-03-01
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11232739
  • Product description4-AMINO-1,8-NAPHTHALIMIDE 97%
  • Packaging5g
  • Price$466
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2616AL 4-Amino-1,8-naphthalimide 250mg $127 2021-12-16 Buy
Alfa Aesar J64358 4-Amino-1,8-naphthalimide, 95% 100mg $48.65 2024-03-01 Buy
Alfa Aesar J64358 4-Amino-1,8-naphthalimide, 95% 1g $201.65 2024-03-01 Buy
Alichem 1742956 6-Amino-1H-benzo[de]isoquinoline-1,3(2H)-dione 10g $1022.42 2021-12-16 Buy
Alichem 1742956 6-Amino-1H-benzo[de]isoquinoline-1,3(2H)-dione 5g $925.41 2021-12-16 Buy
American Custom Chemicals Corporation CHM0011463 4-AMINO-1,8-NAPHTHALIMIDE 95.00% 20MG $618.73 2021-12-16 Buy
Biosynth Carbosynth FA67151 4-Amino-1,8-naphthalimide 250mg $57.5 2021-12-16 Buy
Biosynth Carbosynth FA67151 4-Amino-1,8-naphthalimide 500mg $90 2021-12-16 Buy
Biosynth Carbosynth FA67151 4-Amino-1,8-naphthalimide 1g $140 2021-12-16 Buy
Biosynth Carbosynth FA67151 4-Amino-1,8-naphthalimide 2g $254 2021-12-16 Buy
Biosynth Carbosynth FA67151 4-Amino-1,8-naphthalimide 5G $550 2021-12-16 Buy
Cayman Chemical 18509 4-amino-1,8-Naphthalimide ≥95% 10mg $44 2024-03-01 Buy
Cayman Chemical 18509 4-amino-1,8-Naphthalimide ≥95% 50mg $193 2024-03-01 Buy
Cayman Chemical 18509 4-amino-1,8-Naphthalimide ≥95% 100mg $341 2024-03-01 Buy
Cayman Chemical 18509 4-amino-1,8-Naphthalimide ≥95% 250mg $745 2024-03-01 Buy
Crysdot CD11232739 4-AMINO-1,8-NAPHTHALIMIDE 97% 5g $466 2021-12-16 Buy
Next Last

Properties

Melting point :360 °C
Boiling point :352.04°C (rough estimate)
Density :1.105 g/mL at 25 °C(lit.)
vapor pressure :0Pa at 25℃
refractive index :1.6000 (estimate)
storage temp. :-20°C
solubility :Soluble in DMSO
form :Orange solid.
pka :9.53±0.20(Predicted)
color :Yellow to brown
Water Solubility :354mg/L at 25℃
LogP :1.08
CAS DataBase Reference :1742-95-6
EPA Substance Registry System :1H-Benz[de]isoquinoline-1,3(2H)-dione, 6-amino- (1742-95-6)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis, particularly in response to reactive oxygen and nitrogen species. 4-amino-1,8-Naphthalimide (4-ANI) is an inhibitor of PARP (IC50 = 180 nM). It blocks radiation-induced PARP in cancer cells, potentiating the cytotoxicity of γ-radiation, although it is not cytotoxic in the absence of radiation. 4-ANI is used to study the role of PARP activity in various cell systems.

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1,8-Naphthalimide 4-Amino-1,8-naphthalic anhydride

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Suppliers and manufacturers

TargetMol Chemicals Inc.
4-amino-1,8-Naphthalimide
$53.00 /25mg
4-amino-1,8-Naphthalimide CAS:1742-95-6
Shenzhen Nexconn Pharmatechs Ltd
CONIER CHEM AND PHARMA LIMITED
Dayang Chem (Hangzhou) Co.,Ltd.
GIHI CHEMICALS CO.,LIMITED
LEAPCHEM CO., LTD.
Aladdin Scientific
Amadis Chemical Company Limited Meryer (Shanghai) Chemical Technology Co., Ltd. 3B Pharmachem (Wuhan) International Co.,Ltd.