3-Cyano-4-phenyl-6-(3-bromo-6-hydroxy)phenyl-2(1H)-pyridone
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- $27 - $2097.8
- Product name: 3-Cyano-4-phenyl-6-(3-bromo-6-hydroxy)phenyl-2(1H)-pyridone
- CAS: 491871-58-0
- MF: C18H11BrN2O2
- MW: 367.2
- EINECS:
- MDL Number:MFCD00276275
- Synonyms:3-Cyano-4-phenyl-6-(3-bromo-6-hydroxy)phenyl-2(1H)-pyridone;TCS PIM-1 1;SC 204330;6-(5-Bromo-2-hydroxyphenyl)-1,2-dihydro-2-oxo-4-phenyl-3-pyridinecarbonitrile;TCS PIM-1;TCS PIM-1 1, >=98%;SC 204330; TCS PIM 1-1;CS-1482
27 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- ApexBio Technology
- Biorbyt Ltd
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Tocris
- TRC
- Usbiological
Package
- 1mg
- 50
- 5mg
- 10
- 10mg
- 50mg
- 100mg
- 250mg
- 1000mg
- 1g
- 10mM(in 1mL DMSO)
- ManufacturerAK Scientific
- Product numberJ57518
- Product descriptionTCSPIM-11
- Packaging5mg
- Price$62
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberSYN5483
- Product descriptionTCSPIM-11
- Packaging100mg
- Price$931
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA118376
- Product descriptionTCSPIM-11 98+%
- Packaging1mg
- Price$27
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA118376
- Product descriptionTCSPIM-11 98+%
- Packaging5mg
- Price$46
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA118376
- Product descriptionTCSPIM-11 98+%
- Packaging10mg
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA118376
- Product descriptionTCSPIM-11 98+%
- Packaging50mg
- Price$102
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA118376
- Product descriptionTCSPIM-11 98+%
- Packaging1g
- Price$657
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4521
- Product descriptionTCSPIM-11
- Packaging10mg
- Price$108
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4521
- Product descriptionTCSPIM-11
- Packaging10mM(in 1mL DMSO)
- Price$119
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181333
- Product descriptionTCS PIM-1 1 >98%
- Packaging100mg
- Price$542.3
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181333
- Product descriptionTCS PIM-1 1 >98%
- Packaging250mg
- Price$1060.8
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181333
- Product descriptionTCS PIM-1 1 >98%
- Packaging1000mg
- Price$2097.8
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number16286
- Product descriptionTCS PIM-1 1 ≥98%
- Packaging5mg
- Price$97
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16286
- Product descriptionTCS PIM-1 1 ≥98%
- Packaging10mg
- Price$155
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16286
- Product descriptionTCS PIM-1 1 ≥98%
- Packaging50mg
- Price$360
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16286
- Product descriptionTCS PIM-1 1 ≥98%
- Packaging100mg
- Price$672
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | J57518 | TCSPIM-11 | 5mg | $62 | 2021-12-16 | Buy |
| AK Scientific | SYN5483 | TCSPIM-11 | 100mg | $931 | 2021-12-16 | Buy |
| Ambeed | A118376 | TCSPIM-11 98+% | 1mg | $27 | 2021-12-16 | Buy |
| Ambeed | A118376 | TCSPIM-11 98+% | 5mg | $46 | 2021-12-16 | Buy |
| Ambeed | A118376 | TCSPIM-11 98+% | 10mg | $60 | 2021-12-16 | Buy |
| Ambeed | A118376 | TCSPIM-11 98+% | 50mg | $102 | 2021-12-16 | Buy |
| Ambeed | A118376 | TCSPIM-11 98+% | 1g | $657 | 2021-12-16 | Buy |
| ApexBio Technology | A4521 | TCSPIM-11 | 10mg | $108 | 2021-12-16 | Buy |
| ApexBio Technology | A4521 | TCSPIM-11 | 10mM(in 1mL DMSO) | $119 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181333 | TCS PIM-1 1 >98% | 100mg | $542.3 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181333 | TCS PIM-1 1 >98% | 250mg | $1060.8 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181333 | TCS PIM-1 1 >98% | 1000mg | $2097.8 | 2021-12-16 | Buy |
| Cayman Chemical | 16286 | TCS PIM-1 1 ≥98% | 5mg | $97 | 2024-03-01 | Buy |
| Cayman Chemical | 16286 | TCS PIM-1 1 ≥98% | 10mg | $155 | 2024-03-01 | Buy |
| Cayman Chemical | 16286 | TCS PIM-1 1 ≥98% | 50mg | $360 | 2024-03-01 | Buy |
| Cayman Chemical | 16286 | TCS PIM-1 1 ≥98% | 100mg | $672 | 2024-03-01 | Buy |
Properties
Boiling point :592.6±50.0 °C(Predicted)
Density :1.63±0.1 g/cm3(Predicted)
storage temp. :Store at +4°C
solubility :insoluble in H2O; insoluble in EtOH; ≥12.8 mg/mL in DMSO
form :solid
pka :6.93±0.10(Predicted)
color :Light yellow to yellow
Density :1.63±0.1 g/cm3(Predicted)
storage temp. :Store at +4°C
solubility :insoluble in H2O; insoluble in EtOH; ≥12.8 mg/mL in DMSO
form :solid
pka :6.93±0.10(Predicted)
color :Light yellow to yellow
Safety Information
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Description
The proto-oncogene serine/threonine-protein kinases, Pim-1 and Pim-2, are enzymes involved in cytokine signaling and participate in various signal transduction pathways, including cell growth, differentiation, and apoptosis. Their overexpression has been implicated in prostate cancer, some forms of leukemia, and lymphoma. TCS PIM-1 1 is an ATP-competitive Pim-1 kinase inhibitor (IC50 = 50 nM) that displays selectivity over the related kinases, Pim-2 and MEK1/2 (IC50s = >20 μM).Suppliers and manufacturers
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Wuhan Topule Biopharmaceutical Co., Ltd
Aladdin Scientific
Amadis Chemical Company Limited
