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ChemicalBook >> CAS DataBase List >> 4E1RCat

4E1RCat

4E1RCat price.
  • $37 - $3000
  • Product name: 4E1RCat
  • CAS: 328998-25-0
  • MF: C28H18N2O6
  • MW: 478.45
  • EINECS:
  • MDL Number:MFCD01931282
  • Synonyms:4E1RCat;Benzoic acid, 4-[2,3-dihydro-3-[[5-(4-nitrophenyl)-2-furanyl]Methylene]-2-oxo-5-phenyl-1H-pyrrol-1-yl]-;4-[(3E)-3-[[5-(4-Nitrophenyl)furan-2-yl]methylidene]-2-oxo-5-phenyl-2,3-dihydro-1H-pyrrol-1-yl]benzoic acid;4-[(3E)-3-[[5-(4-nitrophenyl)furan-2-yl]methylidene]-2-oxo-5-phenylpyrrol-1-yl]benzoic acid;4-[2,3-Dihydro-3-[[5-(4-nitrophenyl)-2-furanyl]methylene]-2-oxo-5-phenyl-1H-pyrrol-1-yl]benzoic acid;CS-1228;inhibit,Inhibitor,4E-1rcat,4E1rcat,Eukaryotic Initiation Factor (eIF),Autophagy;4-(3-((5-(4-Nitrophenyl)furan-2-yl)methylene)-2-oxo-5-phenyl-2,3-dihydro-1H-pyrrol-1-yl)benzoic acid
Price34 Properties Safety Information Description
34 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 200mg
  • 500mg
  • 1g
  • 250mg
  • 10mM(in 1mL DMSO)
  • ManufacturerAK Scientific
  • Product number2170AH
  • Product description(E)-4-(3-((5-(4-Nitrophenyl)furan-2-yl)methylene)-2-oxo-5-phenyl-2,3-dihydro-1H-pyrrol-1-yl)benzoicacid
  • Packaging50mg
  • Price$531
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA940826
  • Product description4E1RCat 98+%
  • Packaging5mg
  • Price$210
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA940826
  • Product description4E1RCat 98+%
  • Packaging10mg
  • Price$272
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA940826
  • Product description4E1RCat 98+%
  • Packaging50mg
  • Price$458
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA940826
  • Product description4E1RCat 98+%
  • Packaging100mg
  • Price$595
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB3697
  • Product description4E1RCat
  • Packaging5mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB3697
  • Product description4E1RCat
  • Packaging10mM(in 1mL DMSO)
  • Price$140
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBE177466
  • Product description4E1RCAt NEW
  • Packaging25mg
  • Price$367.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBE177466
  • Product description4E1RCAt NEW
  • Packaging50mg
  • Price$460
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBE177466
  • Product description4E1RCAt NEW
  • Packaging100mg
  • Price$610
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBE177466
  • Product description4E1RCAt NEW
  • Packaging250mg
  • Price$925
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBE177466
  • Product description4E1RCAt NEW
  • Packaging500mg
  • Price$1200
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number18399
  • Product description4E1RCat ≥98%
  • Packaging1mg
  • Price$37
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18399
  • Product description4E1RCat ≥98%
  • Packaging5mg
  • Price$108
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18399
  • Product description4E1RCat ≥98%
  • Packaging10mg
  • Price$161
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM161560
  • Product description(Z)-4-(3-((5-(4-nitrophenyl)furan-2-yl)methylene)-2-oxo-5-phenyl-2,3-dihydro-1H-pyrrol-1-yl)benzoicacid 98%
  • Packaging50mg
  • Price$408
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2170AH (E)-4-(3-((5-(4-Nitrophenyl)furan-2-yl)methylene)-2-oxo-5-phenyl-2,3-dihydro-1H-pyrrol-1-yl)benzoicacid 50mg $531 2021-12-16 Buy
Ambeed A940826 4E1RCat 98+% 5mg $210 2021-12-16 Buy
Ambeed A940826 4E1RCat 98+% 10mg $272 2021-12-16 Buy
Ambeed A940826 4E1RCat 98+% 50mg $458 2021-12-16 Buy
Ambeed A940826 4E1RCat 98+% 100mg $595 2021-12-16 Buy
ApexBio Technology B3697 4E1RCat 5mg $70 2021-12-16 Buy
ApexBio Technology B3697 4E1RCat 10mM(in 1mL DMSO) $140 2021-12-16 Buy
Biosynth Carbosynth BE177466 4E1RCAt NEW 25mg $367.5 2021-12-16 Buy
Biosynth Carbosynth BE177466 4E1RCAt NEW 50mg $460 2021-12-16 Buy
Biosynth Carbosynth BE177466 4E1RCAt NEW 100mg $610 2021-12-16 Buy
Biosynth Carbosynth BE177466 4E1RCAt NEW 250mg $925 2021-12-16 Buy
Biosynth Carbosynth BE177466 4E1RCAt NEW 500mg $1200 2021-12-16 Buy
Cayman Chemical 18399 4E1RCat ≥98% 1mg $37 2024-03-01 Buy
Cayman Chemical 18399 4E1RCat ≥98% 5mg $108 2024-03-01 Buy
Cayman Chemical 18399 4E1RCat ≥98% 10mg $161 2024-03-01 Buy
Chemenu CM161560 (Z)-4-(3-((5-(4-nitrophenyl)furan-2-yl)methylene)-2-oxo-5-phenyl-2,3-dihydro-1H-pyrrol-1-yl)benzoicacid 98% 50mg $408 2021-12-16 Buy
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Properties

Boiling point :764.8±60.0 °C(Predicted)
Density :1.423±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ≥5mg/mL
form :powder
pka :4.23±0.10(Predicted)
color :brown to dark brown

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

4E1RCat is an inhibitor of the eIF4F translation initiation complex that blocks eIF4E:eIF4G and eIF4E:4E-BP1 interactions. It has been shown to prevent the assembly of the eIF4F complex and to inhibit cap-dependent translation with an IC50 value of ~4 μM. 4E1RCat was shown to reverse tumor chemoresistance in a mouse model of lymphoma by sensitizing cells to the proapoptotic action of DNA damage.

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Suppliers and manufacturers

career henan chemical co
4-[(3E)-3-[[5-(4-nitrophenyl)furan-2-yl]methylidene]-2-oxo-5-phenylpyrrol-1-yl]benzoic acid
$1.00 /1KG
4-[(3E)-3-[[5-(4-nitrophenyl)furan-2-yl]methylidene]-2-oxo-5-phenylpyrrol-1-yl]benzoic acid CAS:328998-25-0
ATK CHEMICAL COMPANY LIMITED
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