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ChemicalBook >> CAS DataBase List >> N,N'-dimethyl-N,N'-bis(mercaptoacetyl)hydrazine

N,N'-dimethyl-N,N'-bis(mercaptoacetyl)hydrazine

N,N'-dimethyl-N,N'-bis(mercaptoacetyl)hydrazine price.
  • $45 - $1456
  • Product name: N,N'-dimethyl-N,N'-bis(mercaptoacetyl)hydrazine
  • CAS: 515880-75-8
  • MF: C24H24N4O2
  • MW: 400.47
  • EINECS:
  • MDL Number:MFCD18452839
  • Synonyms:4-[2-[4-(3-phenylpyrazolo[1,5-a]pyrimidin-6-yl)phenoxy]ethyl]morpholine;N,N'-dimethyl-N,N'-bis(mercaptoacetyl)hydrazine;DMH-4;6-[4-[2-(4-Morpholinyl)ethoxy]phenyl]-3-phenylpyrazolo[1,5-a]pyriMidine;Pyrazolo[1,5-a]pyrimidine, 6-[4-[2-(4-morpholinyl)ethoxy]phenyl]-3-phenyl-;DMH4,DMH-4
15 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 5mg
  • 25mg
  • 10
  • 1mg
  • 10mg
  • 50mg
  • ManufacturerAK Scientific
  • Product number9588CN
  • Product description4-[2-[4-(3-Phenylpyrazolo[1,5-a]pyrimidin-6-yl)phenoxy]ethyl]morpholine
  • Packaging1mg
  • Price$147
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberSYN5443
  • Product descriptionDMH4
  • Packaging10mg
  • Price$217
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberSYN5443
  • Product descriptionDMH4
  • Packaging50mg
  • Price$757
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0001468
  • Product descriptionDMH-4 98.00%
  • Packaging10MG
  • Price$750.75
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5611
  • Product descriptionDMH4
  • Packaging10mg
  • Price$345
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5611
  • Product descriptionDMH4
  • Packaging50mg
  • Price$1456
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number27653
  • Product descriptionDMH4
  • Packaging25mg
  • Price$437
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number27653
  • Product descriptionDMH4
  • Packaging10mg
  • Price$198
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number27653
  • Product descriptionDMH4
  • Packaging5mg
  • Price$121
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number27653
  • Product descriptionDMH4
  • Packaging1mg
  • Price$45
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberD8696
  • Product descriptionDMH4 >99.0% (HPLC)
  • Packaging5mg
  • Price$154
  • Updated2022-05-15
  • Buy
  • ManufacturerTocris
  • Product number4471
  • Product descriptionDMH4 ≥98%(HPLC)
  • Packaging10
  • Price$231
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberD494150
  • Product descriptionDMH4
  • Packaging10mg
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number255170
  • Product descriptionDMH4
  • Packaging10mg
  • Price$495
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number010866
  • Product descriptionDMH 4
  • Packaging10mg
  • Price$460
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 9588CN 4-[2-[4-(3-Phenylpyrazolo[1,5-a]pyrimidin-6-yl)phenoxy]ethyl]morpholine 1mg $147 2021-12-16 Buy
AK Scientific SYN5443 DMH4 10mg $217 2021-12-16 Buy
AK Scientific SYN5443 DMH4 50mg $757 2021-12-16 Buy
American Custom Chemicals Corporation INB0001468 DMH-4 98.00% 10MG $750.75 2021-12-16 Buy
ApexBio Technology B5611 DMH4 10mg $345 2021-12-16 Buy
ApexBio Technology B5611 DMH4 50mg $1456 2021-12-16 Buy
Cayman Chemical 27653 DMH4 25mg $437 2024-03-01 Buy
Cayman Chemical 27653 DMH4 10mg $198 2024-03-01 Buy
Cayman Chemical 27653 DMH4 5mg $121 2024-03-01 Buy
Cayman Chemical 27653 DMH4 1mg $45 2024-03-01 Buy
Sigma-Aldrich D8696 DMH4 >99.0% (HPLC) 5mg $154 2022-05-15 Buy
Tocris 4471 DMH4 ≥98%(HPLC) 10 $231 2021-12-16 Buy
TRC D494150 DMH4 10mg $160 2021-12-16 Buy
Usbiological 255170 DMH4 10mg $495 2021-12-16 Buy
Usbiological 010866 DMH 4 10mg $460 2021-12-16 Buy

Properties

Density :1.25±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble20mg/mL
pka :6.28±0.10(Predicted)
form :powder
color :off-white to brown

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

DMH4 is an inhibitor of VEGF receptor 2 (VEGFR2; IC50 = 0.16 μM in a cell-free assay) and a derivative of dorsomorphin . It selectively inhibits VEGFR2 over activin receptor-like kinase 2 (ALK2), ALK5, and AMPK (IC50s = 3.5, >30, and 8 μM, respectively, in a cell-free assay). DMH4 inhibits growth of H460 and A549 human lung cancer cells (GI50s = 13.3 and 2.8 μM, respectively) and reduces VEGF-induced tubule formation in human umbilical vein endothelial cells (HUVECs; IC50 = 1 μM).