N,N'-dimethyl-N,N'-bis(mercaptoacetyl)hydrazine
- $45 - $1456
- Product name: N,N'-dimethyl-N,N'-bis(mercaptoacetyl)hydrazine
- CAS: 515880-75-8
- MF: C24H24N4O2
- MW: 400.47
- EINECS:
- MDL Number:MFCD18452839
- Synonyms:4-[2-[4-(3-phenylpyrazolo[1,5-a]pyrimidin-6-yl)phenoxy]ethyl]morpholine;N,N'-dimethyl-N,N'-bis(mercaptoacetyl)hydrazine;DMH-4;6-[4-[2-(4-Morpholinyl)ethoxy]phenyl]-3-phenylpyrazolo[1,5-a]pyriMidine;Pyrazolo[1,5-a]pyrimidine, 6-[4-[2-(4-morpholinyl)ethoxy]phenyl]-3-phenyl-;DMH4,DMH-4
15 prices
Selected condition:
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 5mg
- 25mg
- 10
- 1mg
- 10mg
- 50mg
- ManufacturerAK Scientific
- Product number9588CN
- Product description4-[2-[4-(3-Phenylpyrazolo[1,5-a]pyrimidin-6-yl)phenoxy]ethyl]morpholine
- Packaging1mg
- Price$147
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberSYN5443
- Product descriptionDMH4
- Packaging10mg
- Price$217
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberSYN5443
- Product descriptionDMH4
- Packaging50mg
- Price$757
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0001468
- Product descriptionDMH-4 98.00%
- Packaging10MG
- Price$750.75
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5611
- Product descriptionDMH4
- Packaging10mg
- Price$345
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5611
- Product descriptionDMH4
- Packaging50mg
- Price$1456
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number27653
- Product descriptionDMH4
- Packaging25mg
- Price$437
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number27653
- Product descriptionDMH4
- Packaging10mg
- Price$198
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number27653
- Product descriptionDMH4
- Packaging5mg
- Price$121
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number27653
- Product descriptionDMH4
- Packaging1mg
- Price$45
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberD8696
- Product descriptionDMH4 >99.0% (HPLC)
- Packaging5mg
- Price$154
- Updated2022-05-15
- Buy
- ManufacturerTocris
- Product number4471
- Product descriptionDMH4 ≥98%(HPLC)
- Packaging10
- Price$231
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberD494150
- Product descriptionDMH4
- Packaging10mg
- Price$160
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number255170
- Product descriptionDMH4
- Packaging10mg
- Price$495
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number010866
- Product descriptionDMH 4
- Packaging10mg
- Price$460
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 9588CN | 4-[2-[4-(3-Phenylpyrazolo[1,5-a]pyrimidin-6-yl)phenoxy]ethyl]morpholine | 1mg | $147 | 2021-12-16 | Buy |
AK Scientific | SYN5443 | DMH4 | 10mg | $217 | 2021-12-16 | Buy |
AK Scientific | SYN5443 | DMH4 | 50mg | $757 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | INB0001468 | DMH-4 98.00% | 10MG | $750.75 | 2021-12-16 | Buy |
ApexBio Technology | B5611 | DMH4 | 10mg | $345 | 2021-12-16 | Buy |
ApexBio Technology | B5611 | DMH4 | 50mg | $1456 | 2021-12-16 | Buy |
Cayman Chemical | 27653 | DMH4 | 25mg | $437 | 2024-03-01 | Buy |
Cayman Chemical | 27653 | DMH4 | 10mg | $198 | 2024-03-01 | Buy |
Cayman Chemical | 27653 | DMH4 | 5mg | $121 | 2024-03-01 | Buy |
Cayman Chemical | 27653 | DMH4 | 1mg | $45 | 2024-03-01 | Buy |
Sigma-Aldrich | D8696 | DMH4 >99.0% (HPLC) | 5mg | $154 | 2022-05-15 | Buy |
Tocris | 4471 | DMH4 ≥98%(HPLC) | 10 | $231 | 2021-12-16 | Buy |
TRC | D494150 | DMH4 | 10mg | $160 | 2021-12-16 | Buy |
Usbiological | 255170 | DMH4 | 10mg | $495 | 2021-12-16 | Buy |
Usbiological | 010866 | DMH 4 | 10mg | $460 | 2021-12-16 | Buy |
Properties
Density :1.25±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble20mg/mL
pka :6.28±0.10(Predicted)
form :powder
color :off-white to brown
storage temp. :2-8°C
solubility :DMSO: soluble20mg/mL
pka :6.28±0.10(Predicted)
form :powder
color :off-white to brown
Safety Information
Symbol(GHS): | |||||||||||||||
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Signal word: | Warning | ||||||||||||||
Hazard statements: |
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Precautionary statements: |
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Description
DMH4 is an inhibitor of VEGF receptor 2 (VEGFR2; IC50 = 0.16 μM in a cell-free assay) and a derivative of dorsomorphin . It selectively inhibits VEGFR2 over activin receptor-like kinase 2 (ALK2), ALK5, and AMPK (IC50s = 3.5, >30, and 8 μM, respectively, in a cell-free assay). DMH4 inhibits growth of H460 and A549 human lung cancer cells (GI50s = 13.3 and 2.8 μM, respectively) and reduces VEGF-induced tubule formation in human umbilical vein endothelial cells (HUVECs; IC50 = 1 μM).Suppliers and manufacturers
Hangzhou MolCore BioPharmatech Co.,Ltd.
J & K SCIENTIFIC LTD.
Chemsky (shanghai) International Co.,Ltd
ShangHai KenEn Chemical Technology Co., Ltd.
EMMX Biotechnology LLC
Shanghai EFE Biological Technology Co., Ltd.
Shenzhen Regent Biochemical Technology Co., Ltd.
Shenzhen Polymeri Biochemical Technology Co., Ltd.
BOC Sciences