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ChemicalBook >> CAS DataBase List >> N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine

N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine

N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine price.
  • $44 - $2048
  • Product name: N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine
  • CAS: 519178-28-0
  • MF: C20H16F3N7O2
  • MW: 443.38
  • EINECS:247-759-6
  • MDL Number:MFCD16875436
  • Synonyms:TNP;N2-(m-Trifluorobenzyl), N6-(p-nitrobenzyl)purine;N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine;N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-9H-Purine-2,6-diamine;IP3K Inhibitor;IP6K Inhibitor ;IP6K1 inhibitor TNP (TNP);IP6K Inhibitor - CAS 519178-28-0 - Calbiochem
Price16 Properties Safety Information Description
16 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • CSNpharm
  • Sigma-Aldrich
  • Tocris
  • Usbiological
Package
  • 10
  • 1mg
  • 5MG
  • 10mg
  • 25MG
  • 50mg
  • 100mg
  • ManufacturerAK Scientific
  • Product number7354BB
  • Product descriptionIP3KInhibitor
  • Packaging50mg
  • Price$1018
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0156658
  • Product descriptionTNP 95.00%
  • Packaging5MG
  • Price$735.63
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0156658
  • Product descriptionTNP 95.00%
  • Packaging25MG
  • Price$1150.91
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7547
  • Product descriptionTNP
  • Packaging10mg
  • Price$331
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7547
  • Product descriptionTNP
  • Packaging100mg
  • Price$2048
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number21189
  • Product descriptionTNP ≥98%
  • Packaging1mg
  • Price$44
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21189
  • Product descriptionTNP ≥98%
  • Packaging5mg
  • Price$143
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21189
  • Product descriptionTNP ≥98%
  • Packaging10mg
  • Price$220
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21189
  • Product descriptionTNP ≥98%
  • Packaging50mg
  • Price$876
  • Updated2024-03-01
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN22432
  • Product descriptionIP3KInhibitor
  • Packaging5mg
  • Price$96
  • Updated2021-12-16
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN22432
  • Product descriptionIP3KInhibitor
  • Packaging10mg
  • Price$136
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberT3955
  • Product descriptionTNP ≥95% (HPLC)
  • Packaging5mg
  • Price$132.6
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number406170
  • Product descriptionIP6K Inhibitor - CAS 519178-28-0 - Calbiochem The IP6K Inhibitor, also referenced under CAS 519178-28-0, controls the biological activity of IP6K.
  • Packaging5mg
  • Price$216
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberT3955
  • Product descriptionTNP ≥95% (HPLC)
  • Packaging25mg
  • Price$683
  • Updated2024-03-01
  • Buy
  • ManufacturerTocris
  • Product number3946
  • Product descriptionTNP ≥97%(HPLC)
  • Packaging10
  • Price$212
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number256942
  • Product descriptionTNP
  • Packaging10mg
  • Price$466
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 7354BB IP3KInhibitor 50mg $1018 2021-12-16 Buy
American Custom Chemicals Corporation CHM0156658 TNP 95.00% 5MG $735.63 2021-12-16 Buy
American Custom Chemicals Corporation CHM0156658 TNP 95.00% 25MG $1150.91 2021-12-16 Buy
ApexBio Technology B7547 TNP 10mg $331 2021-12-16 Buy
ApexBio Technology B7547 TNP 100mg $2048 2021-12-16 Buy
Cayman Chemical 21189 TNP ≥98% 1mg $44 2024-03-01 Buy
Cayman Chemical 21189 TNP ≥98% 5mg $143 2024-03-01 Buy
Cayman Chemical 21189 TNP ≥98% 10mg $220 2024-03-01 Buy
Cayman Chemical 21189 TNP ≥98% 50mg $876 2024-03-01 Buy
CSNpharm CSN22432 IP3KInhibitor 5mg $96 2021-12-16 Buy
CSNpharm CSN22432 IP3KInhibitor 10mg $136 2021-12-16 Buy
Sigma-Aldrich T3955 TNP ≥95% (HPLC) 5mg $132.6 2024-03-01 Buy
Sigma-Aldrich 406170 IP6K Inhibitor - CAS 519178-28-0 - Calbiochem The IP6K Inhibitor, also referenced under CAS 519178-28-0, controls the biological activity of IP6K. 5mg $216 2024-03-01 Buy
Sigma-Aldrich T3955 TNP ≥95% (HPLC) 25mg $683 2024-03-01 Buy
Tocris 3946 TNP ≥97%(HPLC) 10 $212 2021-12-16 Buy
Usbiological 256942 TNP 10mg $466 2021-12-16 Buy

Properties

Boiling point :723.4±70.0 °C(Predicted)
Density :1.543±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ≥10mg/mL
pka :10.51±0.10(Predicted)
form :Yellow solid
color :yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H300 Fatal if swallowed Acute toxicity,oral Category 1, 2 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

IP3K Inhibitor is a cell-permeable 2,6-disubstituted purine compound that acts as a selective, ATP-competitive inhibitor of IP 3-K (IC50 = 10.2 M), the kinase that catalyzes the conversion of IP3 to IP4. Induces elevated cellular IP3 level and Ca2+-release in a dose-dependent manner (5 to 20 M in HL60 cells). IP3K Inhibitor exhibits negligible inhibitory effect on Cdk1 (IC50 >100 M) and two other IP3 metabolizing enzymes, PLC and IP3 5-ppase, even at concentrations as high as 200 M. IP3K Inhibitor is a useful alternative to the non-cell-permeable IP3 or IP3 analogs for studies involving intact cells.

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Suppliers and manufacturers

Career Henan Chemica Co
Wuhan Topule Biopharmaceutical Co., Ltd
Aladdin Scientific Sigma-Aldrich EMMX Biotechnology LLC Shanghai EFE Biological Technology Co., Ltd. Shanghai Rechem science Co., Ltd. MQ (shanghai) Pharmaceuticals Co., Ltd. BOC Sciences DC Chemicals