N-ETHYL-9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-AMIDE
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- $54 - $410
- Product name: N-ETHYL-9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-AMIDE
- CAS: 54130-36-8
- MF: C22H39NO4
- MW: 381.55
- EINECS:
- MDL Number:MFCD03411992
- Synonyms:N-ETHYL-9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-AMIDE;PROSTAGLANDIN F2ALPHA ETHYL AMIDE;PGF2ALPHA-NET;Prostaglandin F2α ethyl amide;(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]-N-ethylhept-5-enamide;Prosta-5,13-dien-1-amide, N-ethyl-9,11,15-trihydroxy-, (5Z,9α,11α,13E,15S)- (9CI);Prostaglandin F2α ethyl amide
4 prices
Selected condition:
Brand
- AK Scientific
- Cayman Chemical
Package
- 1mg
- 5mg
- 10mg
- ManufacturerAK Scientific
- Product number1928AH
- Product descriptionN-Ethyl-9alpha,11alpha,15S-trihydroxy-prosta-5Z,13E-dien-1-amide
- Packaging5mg
- Price$355
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number16016
- Product descriptionProstaglandin F2α ethyl amide ≥98%
- Packaging1mg
- Price$54
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16016
- Product descriptionProstaglandin F2α ethyl amide ≥98%
- Packaging5mg
- Price$231
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16016
- Product descriptionProstaglandin F2α ethyl amide ≥98%
- Packaging10mg
- Price$410
- Updated2024-03-01
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 1928AH | N-Ethyl-9alpha,11alpha,15S-trihydroxy-prosta-5Z,13E-dien-1-amide | 5mg | $355 | 2021-12-16 | Buy |
Cayman Chemical | 16016 | Prostaglandin F2α ethyl amide ≥98% | 1mg | $54 | 2024-03-01 | Buy |
Cayman Chemical | 16016 | Prostaglandin F2α ethyl amide ≥98% | 5mg | $231 | 2024-03-01 | Buy |
Cayman Chemical | 16016 | Prostaglandin F2α ethyl amide ≥98% | 10mg | $410 | 2024-03-01 | Buy |
Properties
storage temp. :Store at -20°C
solubility :DMF: 33mg/ml; DMSO: 16 mg/ml; Ethanol: 20 mg/ml; PBS (pH 7.2): 300 μg/ml
solubility :DMF: 33mg/ml; DMSO: 16 mg/ml; Ethanol: 20 mg/ml; PBS (pH 7.2): 300 μg/ml
Safety Information
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Description
Prostaglandin F2α ethyl amide (PGF2α-NEt) is an analog of PGF2α in which the C-1 carboxyl group has been modified to an N-ethyl amide. PG esters have been shown to have ocular hypotensive activity. PG N-ethyl amides were recently introduced as alternative prostaglandin ocular hypotensive prodrugs. Although it has been claimed that PG ethyl amides are not converted to the free acids in vivo, studies in our laboratories have shown that bovine and human corneal tissue converts the N-ethyl amides of various prostaglandins to the free acids with a conversion rate of about 2.5 μg/g corneal tissue/hr. PGF2α-NEt would be expected to show the typical intraocular effects of PGF2α free acid, but with the much slower hydrolysis pharmacokinetics of the PG N-amides.More related product prices
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