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ChemicalBook >> CAS DataBase List >> N-ETHYL-9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-AMIDE

N-ETHYL-9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-AMIDE

N-ETHYL-9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-AMIDE price.
  • $54 - $410
  • Product name: N-ETHYL-9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-AMIDE
  • CAS: 54130-36-8
  • MF: C22H39NO4
  • MW: 381.55
  • EINECS:
  • MDL Number:MFCD03411992
  • Synonyms:N-ETHYL-9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-AMIDE;PROSTAGLANDIN F2ALPHA ETHYL AMIDE;PGF2ALPHA-NET;Prostaglandin F2α ethyl amide;(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]-N-ethylhept-5-enamide;Prosta-5,13-dien-1-amide, N-ethyl-9,11,15-trihydroxy-, (5Z,9α,11α,13E,15S)- (9CI);Prostaglandin F2α ethyl amide
4 prices
Selected condition:
Brand
  • AK Scientific
  • Cayman Chemical
Package
  • 1mg
  • 5mg
  • 10mg
  • ManufacturerAK Scientific
  • Product number1928AH
  • Product descriptionN-Ethyl-9alpha,11alpha,15S-trihydroxy-prosta-5Z,13E-dien-1-amide
  • Packaging5mg
  • Price$355
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number16016
  • Product descriptionProstaglandin F2α ethyl amide ≥98%
  • Packaging1mg
  • Price$54
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16016
  • Product descriptionProstaglandin F2α ethyl amide ≥98%
  • Packaging5mg
  • Price$231
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16016
  • Product descriptionProstaglandin F2α ethyl amide ≥98%
  • Packaging10mg
  • Price$410
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1928AH N-Ethyl-9alpha,11alpha,15S-trihydroxy-prosta-5Z,13E-dien-1-amide 5mg $355 2021-12-16 Buy
Cayman Chemical 16016 Prostaglandin F2α ethyl amide ≥98% 1mg $54 2024-03-01 Buy
Cayman Chemical 16016 Prostaglandin F2α ethyl amide ≥98% 5mg $231 2024-03-01 Buy
Cayman Chemical 16016 Prostaglandin F2α ethyl amide ≥98% 10mg $410 2024-03-01 Buy

Properties

storage temp. :Store at -20°C
solubility :DMF: 33mg/ml; DMSO: 16 mg/ml; Ethanol: 20 mg/ml; PBS (pH 7.2): 300 μg/ml

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H336 May cause drowsiness or dizziness Specific target organ toxicity,single exposure; Narcotic effects Category 3 Warning P261, P271, P304+P340, P312,P403+P233, P405, P501
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P370+P378 In case of fire: Use … for extinction.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P403+P235 Store in a well-ventilated place. Keep cool.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Prostaglandin F2α ethyl amide (PGF2α-NEt) is an analog of PGF2α in which the C-1 carboxyl group has been modified to an N-ethyl amide. PG esters have been shown to have ocular hypotensive activity. PG N-ethyl amides were recently introduced as alternative prostaglandin ocular hypotensive prodrugs. Although it has been claimed that PG ethyl amides are not converted to the free acids in vivo, studies in our laboratories have shown that bovine and human corneal tissue converts the N-ethyl amides of various prostaglandins to the free acids with a conversion rate of about 2.5 μg/g corneal tissue/hr. PGF2α-NEt would be expected to show the typical intraocular effects of PGF2α free acid, but with the much slower hydrolysis pharmacokinetics of the PG N-amides.

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