| Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
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400-9205774 |
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sales@glpbio.cn |
| Products Intro: |
Product Name:Prostaglandin F2α ethyl amide
CAS:54130-36-8
Purity:>98% Package:1mg;10mg;50mg;100mg;
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| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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18818260767 |
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sales@chemegen.com |
| Products Intro: |
Product Name:Prostaglandin F2α ethyl amide
CAS:54130-36-8
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
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021-65675885 18964387627 |
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customer_service@efebio.com |
| Products Intro: |
Product Name:Prostaglandin F2α ethyl amide
CAS:54130-36-8
Purity:98% Package:1mg;5mg;10mg
|
| Company Name: |
Cayman Chemical Company
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| Tel: |
(800) 364-9897 |
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cayman@caymanchem.com |
| Products Intro: |
Product Name:Prostaglandin F2α ethyl amide
CAS:54130-36-8
Package:>98% Remarks:16016
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| | N-ETHYL-9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-AMIDE Basic information |
| Product Name: | N-ETHYL-9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-AMIDE | | Synonyms: | N-ETHYL-9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-AMIDE;PROSTAGLANDIN F2ALPHA ETHYL AMIDE;PGF2ALPHA-NET;Prostaglandin F2α ethyl amide;(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]-N-ethylhept-5-enamide;Prosta-5,13-dien-1-amide, N-ethyl-9,11,15-trihydroxy-, (5Z,9α,11α,13E,15S)- (9CI);Prostaglandin F2α ethyl amide | | CAS: | 54130-36-8 | | MF: | C22H39NO4 | | MW: | 381.55 | | EINECS: | | | Product Categories: | | | Mol File: | 54130-36-8.mol |  |
| | N-ETHYL-9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-AMIDE Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMF: 33mg/ml; DMSO: 16 mg/ml; Ethanol: 20 mg/ml; PBS (pH 7.2): 300 μg/ml |
| | N-ETHYL-9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-AMIDE Usage And Synthesis |
| Description | Prostaglandin F2α ethyl amide (PGF2α-NEt) is an analog of PGF2α in which the C-1 carboxyl group has been modified to an N-ethyl amide. PG esters have been shown to have ocular hypotensive activity. PG N-ethyl amides were recently introduced as alternative prostaglandin ocular hypotensive prodrugs. Although it has been claimed that PG ethyl amides are not converted to the free acids in vivo, studies in our laboratories have shown that bovine and human corneal tissue converts the N-ethyl amides of various prostaglandins to the free acids with a conversion rate of about 2.5 μg/g corneal tissue/hr. PGF2α-NEt would be expected to show the typical intraocular effects of PGF2α free acid, but with the much slower hydrolysis pharmacokinetics of the PG N-amides. |
| | N-ETHYL-9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-AMIDE Preparation Products And Raw materials |
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