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ChemicalBook >> CAS DataBase List >> N1,N4-Di-2-pyridinyl-1,4-benzenedimethanamine

N1,N4-Di-2-pyridinyl-1,4-benzenedimethanamine

N1,N4-Di-2-pyridinyl-1,4-benzenedimethanamine price.
  • $19 - $2814
  • Product name: N1,N4-Di-2-pyridinyl-1,4-benzenedimethanamine
  • CAS: 55778-02-4
  • MF: C18H18N4
  • MW: 290.36
  • EINECS:200-256-5
  • MDL Number:MFCD18086914
  • Synonyms:1,4-Benzenedimethanamine, N1,N4-di-2-pyridinyl-;N1,N4-di-2-pyridinyl-1,4-benzenedimethanamine WZ811;WZ 811 N,N'-Di-2-pyridinyl-1,4-benzenedimethanamine;WZ 811, >=98%;N1,N4-Di-2-pyridinyl-1,4-benzenedimethanamine;WZ 811;N,N'-(1,4-PHENYLENEBIS(METHYLENE))DIPYRIDIN-2-AMINE;N,N'-Di-2-pyridinyl-1,4-benzenedimethanamine
44 prices
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Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Biorbyt Ltd
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 1mg
  • 5mg
  • 10mg
  • 50
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 500mg
  • 1g
  • 1000mg
  • ManufacturerAK Scientific
  • Product numberSYN5661
  • Product descriptionWZ 811
  • Packaging10mg
  • Price$142
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberY0219
  • Product descriptionWZ 811
  • Packaging1g
  • Price$2469
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA220173
  • Product descriptionN,N'-(1,4-Phenylenebis(methylene))bis(pyridin-2-amine) 98+%
  • Packaging10mg
  • Price$98
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA220173
  • Product descriptionN,N'-(1,4-Phenylenebis(methylene))bis(pyridin-2-amine) 98+%
  • Packaging50mg
  • Price$255
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA220173
  • Product descriptionN,N'-(1,4-Phenylenebis(methylene))bis(pyridin-2-amine) 98+%
  • Packaging100mg
  • Price$331
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA220173
  • Product descriptionN,N'-(1,4-Phenylenebis(methylene))bis(pyridin-2-amine) 98+%
  • Packaging1g
  • Price$2814
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0009842
  • Product descriptionN1,N4-DI-2-PYRIDINYL-1,4-BENZENEDIMETHANAMINE 95.00%
  • Packaging10MG
  • Price$223.65
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1466
  • Product descriptionWZ 811
  • Packaging10mg
  • Price$81
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1466
  • Product descriptionWZ 811
  • Packaging50mg
  • Price$226
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1466
  • Product descriptionWZ 811
  • Packaging100mg
  • Price$316
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1466
  • Product descriptionWZ 811
  • Packaging500mg
  • Price$768
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1466
  • Product descriptionWZ 811
  • Packaging1g
  • Price$1268
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS016375
  • Product descriptionN,N'-(1,4-Phenylenebis(methylene))bis(pyridin-2-amine) ≥98%
  • Packaging10mg
  • Price$97
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181180
  • Product descriptionWZ 811 >98%
  • Packaging100mg
  • Price$510
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181180
  • Product descriptionWZ 811 >98%
  • Packaging250mg
  • Price$765
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181180
  • Product descriptionWZ 811 >98%
  • Packaging1000mg
  • Price$1802
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific SYN5661 WZ 811 10mg $142 2021-12-16 Buy
AK Scientific Y0219 WZ 811 1g $2469 2021-12-16 Buy
Ambeed A220173 N,N'-(1,4-Phenylenebis(methylene))bis(pyridin-2-amine) 98+% 10mg $98 2021-12-16 Buy
Ambeed A220173 N,N'-(1,4-Phenylenebis(methylene))bis(pyridin-2-amine) 98+% 50mg $255 2021-12-16 Buy
Ambeed A220173 N,N'-(1,4-Phenylenebis(methylene))bis(pyridin-2-amine) 98+% 100mg $331 2021-12-16 Buy
Ambeed A220173 N,N'-(1,4-Phenylenebis(methylene))bis(pyridin-2-amine) 98+% 1g $2814 2021-12-16 Buy
American Custom Chemicals Corporation API0009842 N1,N4-DI-2-PYRIDINYL-1,4-BENZENEDIMETHANAMINE 95.00% 10MG $223.65 2021-12-16 Buy
ApexBio Technology B1466 WZ 811 10mg $81 2021-12-16 Buy
ApexBio Technology B1466 WZ 811 50mg $226 2021-12-16 Buy
ApexBio Technology B1466 WZ 811 100mg $316 2021-12-16 Buy
ApexBio Technology B1466 WZ 811 500mg $768 2021-12-16 Buy
ApexBio Technology B1466 WZ 811 1g $1268 2021-12-16 Buy
Arctom AS016375 N,N'-(1,4-Phenylenebis(methylene))bis(pyridin-2-amine) ≥98% 10mg $97 2021-12-16 Buy
Biorbyt Ltd orb181180 WZ 811 >98% 100mg $510 2021-12-16 Buy
Biorbyt Ltd orb181180 WZ 811 >98% 250mg $765 2021-12-16 Buy
Biorbyt Ltd orb181180 WZ 811 >98% 1000mg $1802 2021-12-16 Buy

Properties

Melting point :192-194℃ (methanol )
Boiling point :493.2±35.0 °C(Predicted)
Density :1.229±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :DMSO: ≥7mg/mL
pka :6.55±0.10(Predicted)
form :powder
color :white to tan

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

The CXC chemokine receptor-4 (CXCR4) is a G protein-coupled receptor that is specific for stromal cell-derived factor-1 (SDF-1/ CXCL12). Activation of CXCR4 promotes homing of hematopoietic stem cells, chemotaxis and quiescence of lymphocytes, and growth and metastasis of certain cancer cell types. Moreover, CXCR4 on CD4+ T-cells is used by CXCR4-selective HIV forms as a gateway for T-cell infection. WZ811 is a potent inhibitor of binding of an SDF-1 peptide mimic to CXCR4 (EC50 = 0.3 nM). It prevents SDF-1/CXCL12-mediated modulation of cAMP (EC50 = 1.2 nM) in cells and blocks SDF-1-induced Matrigel? invasion by MDA-MB-231 human breast adenocarcinoma cells (EC50 = 5.2 nM). The effectiveness of WZ811 in animals remains to be elucidated.

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