RG108
|
- $42 - $2416
- Product name: RG108
- CAS: 48208-26-0
- MF: C19H14N2O4
- MW: 334.33
- EINECS:
- MDL Number:MFCD08705332
- Synonyms:(S)-2-(1,3-dioxoisoindolin-2-yl)-3-(1H-indol-3-yl)propanoic acid;RG108/RG-108;(S)-3-(Indol-3-yl)-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)propanoic acid;N-Phthaloyl-L-tryptophan;1H-Indole-3-propanoic acid, α-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-, (αS)-;N-Phthaloyl-L-tryptophan (S)-3-(Indol-3-yl)-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)propanoic acid;DNA Methyltransferase Inhibitor;N-Phthalyl-L-tryptophan
46 prices
Selected condition：
Brand
- AK Scientific
- Alfa Aesar
- Ambeed
- ApexBio Technology
- Arctom
- Axon Medchem
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- Chem-Impex
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Labseeker
- Sigma-Aldrich
- TCI Chemical
- TRC
- Usbiological
Package
- 5mg
- 10mg
- 2x10mg
- 20mg
- 25mg
- 50mg
- 100mg
- 2x50mg
- 200MG
- 250mg
- 1g
- 5g
- 10mM(in 1mL DMSO)
- ManufacturerAK Scientific
- Product numberSYN3037
- Product descriptionRG-108
- Packaging10mg
- Price$130
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ64630
- Product descriptionDNA Methyltransferase Inhibitor
- Packaging10mg
- Price$176
- Updated2023-06-20
- Buy
- ManufacturerAmbeed
- Product numberA548158
- Product descriptionRG108 98+%
- Packaging5mg
- Price$42
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA548158
- Product descriptionRG108 98+%
- Packaging10mg
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA548158
- Product descriptionRG108 98+%
- Packaging50mg
- Price$88
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA548158
- Product descriptionRG108 98+%
- Packaging100mg
- Price$111
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA548158
- Product descriptionRG108 98+%
- Packaging250mg
- Price$162
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA548158
- Product descriptionRG108 98+%
- Packaging1g
- Price$383
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA548158
- Product descriptionRG108 98+%
- Packaging5g
- Price$1335
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1913
- Product descriptionRG108
- Packaging10mM(in 1mL DMSO)
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1913
- Product descriptionRG108
- Packaging25mg
- Price$100
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS592942
- Product descriptionRG108 ≥98%
- Packaging5mg
- Price$42
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS592942
- Product descriptionRG108 ≥98%
- Packaging10mg
- Price$54
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS592942
- Product descriptionRG108 ≥98%
- Packaging50mg
- Price$87
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS592942
- Product descriptionRG108 ≥98%
- Packaging100mg
- Price$110
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS592942
- Product descriptionRG108 ≥98%
- Packaging250mg
- Price$160
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | SYN3037 | RG-108 | 10mg | $130 | 2021-12-16 | Buy |
| Alfa Aesar | J64630 | DNA Methyltransferase Inhibitor | 10mg | $176 | 2023-06-20 | Buy |
| Ambeed | A548158 | RG108 98+% | 5mg | $42 | 2021-12-16 | Buy |
| Ambeed | A548158 | RG108 98+% | 10mg | $55 | 2021-12-16 | Buy |
| Ambeed | A548158 | RG108 98+% | 50mg | $88 | 2021-12-16 | Buy |
| Ambeed | A548158 | RG108 98+% | 100mg | $111 | 2021-12-16 | Buy |
| Ambeed | A548158 | RG108 98+% | 250mg | $162 | 2021-12-16 | Buy |
| Ambeed | A548158 | RG108 98+% | 1g | $383 | 2021-12-16 | Buy |
| Ambeed | A548158 | RG108 98+% | 5g | $1335 | 2021-12-16 | Buy |
| ApexBio Technology | A1913 | RG108 | 10mM(in 1mL DMSO) | $60 | 2021-12-16 | Buy |
| ApexBio Technology | A1913 | RG108 | 25mg | $100 | 2021-12-16 | Buy |
| Arctom | AS592942 | RG108 ≥98% | 5mg | $42 | 2021-12-16 | Buy |
| Arctom | AS592942 | RG108 ≥98% | 10mg | $54 | 2021-12-16 | Buy |
| Arctom | AS592942 | RG108 ≥98% | 50mg | $87 | 2021-12-16 | Buy |
| Arctom | AS592942 | RG108 ≥98% | 100mg | $110 | 2021-12-16 | Buy |
| Arctom | AS592942 | RG108 ≥98% | 250mg | $160 | 2021-12-16 | Buy |
Properties
Melting point :192-194℃
Boiling point :606.0±50.0 °C(Predicted)
Density :1.502±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: >10mg/mL
pka :3.62±0.10(Predicted)
form :powder
color :yellow
Sensitive :Light Sensitive
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
CAS DataBase Reference :48208-26-0
Boiling point :606.0±50.0 °C(Predicted)
Density :1.502±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: >10mg/mL
pka :3.62±0.10(Predicted)
form :powder
color :yellow
Sensitive :Light Sensitive
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
CAS DataBase Reference :48208-26-0
Safety Information
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Description
DNA methylation regulates gene expression in normal and malignant cells. RG-108 is a non-nucleoside DNA methyltransferase inhibitor (IC50 = 115 nM in vitro). It significantly reduces the methylation of genomic DNA in cells at 10 μM without detectable toxicity, distinguishing it from nucleoside-based inhibitors like 5-azacytidine. Further, RG-108 inhibits DNA methyltransferase activity by blocking the enzyme active site. Through these actions, RG-108 demethylates and reactivates epigenetically silenced tumor suppressor genes.Related product price
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