RG108 suppliers
RG108
- CAS:
- 48208-26-0
- MF:
- C19H14N2O4
- MW:
- 334.33
Suppliers by country/region
Company Type
Properties
- Melting point:
- 192-194℃
- Boiling point:
- 606.0±50.0 °C(Predicted)
- Density
- 1.502±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- DMSO: >10mg/mL
- pka
- 3.62±0.10(Predicted)
- form
- powder
- color
- yellow
- optical activity
- [α]/D -250 to -310°, c =0.5 in methanol
- Sensitive
- Light Sensitive
- Stability:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
- CAS DataBase Reference
- 48208-26-0
Safety Information
- WGK Germany
- 3
- HS Code
- 2933.99.9701
Use
DNA methylation regulates gene expression in normal and malignant cells. RG-108 is a non-nucleoside DNA methyltransferase inhibitor (IC50 = 115 nM in vitro). It significantly reduces the methylation of genomic DNA in cells at 10 μM without detectable toxicity, distinguishing it from nucleoside-based inhibitors like 5-azacytidine. Further, RG-108 inhibits DNA methyltransferase activity by blocking the enzyme active site. Through these actions, RG-108 demethylates and reactivates epigenetically silenced tumor suppressor genes.
108 supplier list of "RG108"
$1.00/ 1KG
- Product Name:RG108/RG-108
- Products Intro:Purity: 98% | Package: 1KG;1USD
- Company Type: Reagent
- Country/Region: CHINA
- Main Products: Nicotinamide riboside chloride,Curcumin,L(+)-Ascorbic acid,L-Glutamine,Stevioside Basic information
- Product Name:RG108;N-Phthalyl-L-tryptophan
- Products Intro:Purity: 99.78% | Package: 5mg;39USD|10mg;63USD|25mg;119USD | CustNote: REAGENT;FOR LABORATORY USE ONLY
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits
You can find RG108 suppliers,
manufacturers, and distributors from countries such as China, United States and the United Kingdom here.
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