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ChemicalBook >> CAS DataBase List >> N-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]-2-methoxyphenyl]-N'-[1-(2-thiazolyl)ethyl]urea

N-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]-2-methoxyphenyl]-N'-[1-(2-thiazolyl)ethyl]urea

N-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]-2-methoxyphenyl]-N'-[1-(2-thiazolyl)ethyl]urea price.
  • $33 - $3136.5
  • Product name: N-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]-2-methoxyphenyl]-N'-[1-(2-thiazolyl)ethyl]urea
  • CAS: 623142-96-1
  • MF: C24H24N4O5S
  • MW: 480.54
  • EINECS:200-258-5
  • MDL Number:MFCD12024693
  • Synonyms:N-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]-2-methoxyphenyl]-N'-[1-(2-thiazolyl)ethyl]urea;Urea, N-[4-[(6,7-diMethoxy-4-quinolinyl)oxy]-2-Methoxyphenyl]-N'-[1-(2-thiazolyl)ethyl]-;1-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)-2-methoxyphenyl)-3-(1-(thiazol-2-yl)ethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2-methoxyphenyl]-3-[1-(1,3-thiazol-2-yl)ethyl]urea;KI20227; KI-20227; KI 20227;CS-1094;KI20227; KI 20227;Ki20227
Price37 Properties Safety Information Description
37 prices
Selected condition：
Brand
  • Adipogen Life Sciences
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
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  • 1MG
  • 2mg
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  • 1000mg
  • 1g
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1049-M050
  • Product descriptionKi20227 ≥95%
  • Packaging50mg
  • Price$891
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberY0265
  • Product descriptionKI20227
  • Packaging50mg
  • Price$1751
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA691021
  • Product descriptionKi20227 98+%
  • Packaging2mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA691021
  • Product descriptionKi20227 98+%
  • Packaging5mg
  • Price$240
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA691021
  • Product descriptionKi20227 98+%
  • Packaging10mg
  • Price$359
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA691021
  • Product descriptionKi20227 98+%
  • Packaging25mg
  • Price$610
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA691021
  • Product descriptionKi20227 98+%
  • Packaging50mg
  • Price$793
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000640
  • Product description1-(4-(6,7-DIMETHOXYQUINOLIN-4-YLOXY)-2-METHOXYPHENYL)-3-(1-(THIAZOL-2-YL)ETHYL)UREA 95.00%
  • Packaging1MG
  • Price$228.9
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000640
  • Product description1-(4-(6,7-DIMETHOXYQUINOLIN-4-YLOXY)-2-METHOXYPHENYL)-3-(1-(THIAZOL-2-YL)ETHYL)UREA 95.00%
  • Packaging5MG
  • Price$495.55
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3527
  • Product descriptionKi20227
  • Packaging10mg
  • Price$205
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181032
  • Product descriptionKi20227 >98%
  • Packaging100mg
  • Price$838.1
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181032
  • Product descriptionKi20227 >98%
  • Packaging1000mg
  • Price$3136.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD153250
  • Product description1-(4-(6,7-Dimethoxyquinolin-4-yloxy)-2-methoxyphenyl)-3-(1-(thiazol-2-yl)ethyl)urea
  • Packaging2mg
  • Price$59
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD153250
  • Product description1-(4-(6,7-Dimethoxyquinolin-4-yloxy)-2-methoxyphenyl)-3-(1-(thiazol-2-yl)ethyl)urea
  • Packaging5mg
  • Price$117
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD153250
  • Product description1-(4-(6,7-Dimethoxyquinolin-4-yloxy)-2-methoxyphenyl)-3-(1-(thiazol-2-yl)ethyl)urea
  • Packaging10mg
  • Price$203
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD153250
  • Product description1-(4-(6,7-Dimethoxyquinolin-4-yloxy)-2-methoxyphenyl)-3-(1-(thiazol-2-yl)ethyl)urea
  • Packaging25mg
  • Price$405
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences SYN-1049-M050 Ki20227 ≥95% 50mg $891 2021-12-16 Buy
AK Scientific Y0265 KI20227 50mg $1751 2021-12-16 Buy
Ambeed A691021 Ki20227 98+% 2mg $120 2021-12-16 Buy
Ambeed A691021 Ki20227 98+% 5mg $240 2021-12-16 Buy
Ambeed A691021 Ki20227 98+% 10mg $359 2021-12-16 Buy
Ambeed A691021 Ki20227 98+% 25mg $610 2021-12-16 Buy
Ambeed A691021 Ki20227 98+% 50mg $793 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000640 1-(4-(6,7-DIMETHOXYQUINOLIN-4-YLOXY)-2-METHOXYPHENYL)-3-(1-(THIAZOL-2-YL)ETHYL)UREA 95.00% 1MG $228.9 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000640 1-(4-(6,7-DIMETHOXYQUINOLIN-4-YLOXY)-2-METHOXYPHENYL)-3-(1-(THIAZOL-2-YL)ETHYL)UREA 95.00% 5MG $495.55 2021-12-16 Buy
ApexBio Technology A3527 Ki20227 10mg $205 2021-12-16 Buy
Biorbyt Ltd orb181032 Ki20227 >98% 100mg $838.1 2021-12-16 Buy
Biorbyt Ltd orb181032 Ki20227 >98% 1000mg $3136.5 2021-12-16 Buy
Biosynth Carbosynth FD153250 1-(4-(6,7-Dimethoxyquinolin-4-yloxy)-2-methoxyphenyl)-3-(1-(thiazol-2-yl)ethyl)urea 2mg $59 2021-12-16 Buy
Biosynth Carbosynth FD153250 1-(4-(6,7-Dimethoxyquinolin-4-yloxy)-2-methoxyphenyl)-3-(1-(thiazol-2-yl)ethyl)urea 5mg $117 2021-12-16 Buy
Biosynth Carbosynth FD153250 1-(4-(6,7-Dimethoxyquinolin-4-yloxy)-2-methoxyphenyl)-3-(1-(thiazol-2-yl)ethyl)urea 10mg $203 2021-12-16 Buy
Biosynth Carbosynth FD153250 1-(4-(6,7-Dimethoxyquinolin-4-yloxy)-2-methoxyphenyl)-3-(1-(thiazol-2-yl)ethyl)urea 25mg $405 2021-12-16 Buy
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Properties

Boiling point :621.8±55.0 °C(Predicted)
Density :1.327
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :≥48.1 mg/mL in DMSO; insoluble in H2O; ≥8.6 mg/mL in EtOH with gentle warming and ultrasonic
form :Brown powder.
pka :12.03±0.46(Predicted)
color :Off-white to pink

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Ki20227 is an inhibitor of macrophage colony stimulating factor 1 (CSF1) receptor tyrosine kinase (c-Fms; IC50 = 2 nM). It inhibits CSF1-dependent c-Fms phosphorylation in a dose-dependent manner in RAW264.7 cells and reduces CSF1-dependent growth of M-NFS-60 cells (IC50 = 14 nM). Ki20227 suppresses development of TRAP-positive osteoclast-like cells from murine bone marrow (IC50 = 40 nM) and decreases the number and area of osteolytic lesions on femurs and tibiae in a murine A375 subcutaneous xenograft model. Ki20227 also reduces TNF-α infiltration and osteolytic bone destruction in a collagen-induced arthritis (CIA) mouse model.

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Suppliers and manufacturers

career henan chemical co
Ki20227
$1.00 /1g
Ki20227 CAS:623142-96-1
Capot Chemical Co.,Ltd.
ATK CHEMICAL COMPANY LIMITED
Biochempartner
BOC Sciences
CONIER CHEM AND PHARMA LIMITED
Hefei Hirisun Pharmatech Co., Ltd
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
TargetMol Chemicals Inc.