6-Amino-2,3-dihydro-5-[(phenylmethylene)amino]-2-4(1H)-pyrimidineone
![6-Amino-2,3-dihydro-5-[(phenylmethylene)amino]-2-4(1H)-pyrimidineone price.](/CAS/20180808/GIF/64232-83-3.gif)
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- $42 - $1600
- Product name: 6-Amino-2,3-dihydro-5-[(phenylmethylene)amino]-2-4(1H)-pyrimidineone
- CAS: 64232-83-3
- MF: C11H10N4OS
- MW: 246.29
- EINECS:
- MDL Number:MFCD11556233
- Synonyms:6-Amino-2,3-dihydro-5-[(phenylmethylene)amino]-2-4(1H)-pyrimidineone;L189;4(1H)-PyriMidinone, 6-aMino-2,3-dihydro-5-[(phenylMethylene)aMino]-2-thioxo-;(E)-6-amino-5-(benzylideneamino)-2-mercaptopyrimidin-4-ol;6-Amino-2,3-dihydro-5-[(phenylmethylene)amino]-2-thioxo-4(1H)-pyrimidinone;L 189;L189;6-Amino-5-(benzylideneamino)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
24 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Tocris
- TRC
- Usbiological
Package
- 10
- 5MG
- 10mg
- 25mg
- 50mg
- 10mM(in 1mL DMSO)
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product numberX3560
- Product descriptionL189
- Packaging25mg
- Price$298
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0009834
- Product descriptionL-189 95.00%
- Packaging5MG
- Price$458.05
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7426
- Product descriptionL189
- Packaging10mM(in 1mL DMSO)
- Price$42
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7426
- Product descriptionL189
- Packaging5mg
- Price$59
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7426
- Product descriptionL189
- Packaging10mg
- Price$94
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7426
- Product descriptionL189
- Packaging25mg
- Price$196
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7426
- Product descriptionL189
- Packaging50mg
- Price$313
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS568408
- Product descriptionL189 ≥98%
- Packaging10mg
- Price$92
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS568408
- Product descriptionL189 ≥98%
- Packaging25mg
- Price$166
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS568408
- Product descriptionL189 ≥98%
- Packaging100mg
- Price$519
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number18374
- Product descriptionL189 ≥95%
- Packaging5mg
- Price$86
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18374
- Product descriptionL189 ≥95%
- Packaging10mg
- Price$161
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18374
- Product descriptionL189 ≥95%
- Packaging25mg
- Price$379
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18374
- Product descriptionL189 ≥95%
- Packaging50mg
- Price$546
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM294857
- Product description6-Amino-5-(benzylideneamino)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one 98%
- Packaging50mg
- Price$259
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5120
- Product descriptionL189 ≥98.0%
- Packaging10mg
- Price$108
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | X3560 | L189 | 25mg | $298 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0009834 | L-189 95.00% | 5MG | $458.05 | 2021-12-16 | Buy |
| ApexBio Technology | B7426 | L189 | 10mM(in 1mL DMSO) | $42 | 2021-12-16 | Buy |
| ApexBio Technology | B7426 | L189 | 5mg | $59 | 2021-12-16 | Buy |
| ApexBio Technology | B7426 | L189 | 10mg | $94 | 2021-12-16 | Buy |
| ApexBio Technology | B7426 | L189 | 25mg | $196 | 2021-12-16 | Buy |
| ApexBio Technology | B7426 | L189 | 50mg | $313 | 2021-12-16 | Buy |
| Arctom | AS568408 | L189 ≥98% | 10mg | $92 | 2021-12-16 | Buy |
| Arctom | AS568408 | L189 ≥98% | 25mg | $166 | 2021-12-16 | Buy |
| Arctom | AS568408 | L189 ≥98% | 100mg | $519 | 2021-12-16 | Buy |
| Cayman Chemical | 18374 | L189 ≥95% | 5mg | $86 | 2024-03-01 | Buy |
| Cayman Chemical | 18374 | L189 ≥95% | 10mg | $161 | 2024-03-01 | Buy |
| Cayman Chemical | 18374 | L189 ≥95% | 25mg | $379 | 2024-03-01 | Buy |
| Cayman Chemical | 18374 | L189 ≥95% | 50mg | $546 | 2024-03-01 | Buy |
| Chemenu | CM294857 | 6-Amino-5-(benzylideneamino)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one 98% | 50mg | $259 | 2021-12-16 | Buy |
| ChemScene | CS-5120 | L189 ≥98.0% | 10mg | $108 | 2021-12-16 | Buy |
Properties
Melting point :250 °C (decomp)
Density :1.45±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :≥62.5 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
form :solid
pka :8.16±0.60(Predicted)
color :Light yellow to yellow
Density :1.45±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :≥62.5 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
form :solid
pka :8.16±0.60(Predicted)
color :Light yellow to yellow
Safety Information
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Description
L189 is a competitive inhibitor of DNA ligases I, III, and IV (IC50s = 5, 9, and 5 μM, respectively). It blocks DNA binding (Ki = 5 μM for DNA ligase I), increasing the cytotoxicity of DNA-damaging agents, including ionizing radiation. L189 preferentially inhibits the interaction of the ligase with damaged DNA, inhibiting base excision repair and non-homologous end-joining.Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
Career Henan Chemica Co
Chemia Biotechnology（Shanghai） Co., Ltd
InvivoChem
TargetMol Chemicals Inc.
ShenZhen Trendseen Biological Technology Co.,Ltd.
Aladdin Scientific
Amadis Chemical Company Limited
Shanghai Boyle Chemical Co., Ltd.
3B Pharmachem (Wuhan) International Co.,Ltd.