4,5-Dihydro-3-phenyl-5-isoxazoleaceticacid
- $62 - $3000
- Product name: 4,5-Dihydro-3-phenyl-5-isoxazoleaceticacid
- CAS: 6501-72-0
- MF: C11H11NO3
- MW: 205.21
- EINECS:
- MDL Number:MFCD08696167
- Synonyms:4,5-Dihydro-3-phenyl-5-isoxazoleaceticacid;GIT 27;VGX-1027;2-(3-PHENYL-4,5-DIHYDROISOXAZOL-5-YL)ACETIC ACID;3-Phenyl-2-isoxazoline-5-acetic acid;VGX 1027 3-Phenyl-2-isoxazoline-5-acetic acid;(S,R)-3-Phenyl-4,5-dihydro-5-isoxasole acetic acid;2-Isoxazoline-5-acetic acid, 3-phenyl-
32 prices
Selected condition:
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Medical Isotopes, Inc.
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 10mg
- 10
- 5MG
- 25mg
- 50
- 50mg
- 100mg
- 250mg
- 1g
- 1000mg
- ManufacturerAK Scientific
- Product number2792AH
- Product description4,5-Dihydro-3-phenyl-5-isoxazoleaceticacid
- Packaging1g
- Price$959
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCYT0000086
- Product descriptionGIT-27 95.00%
- Packaging5MG
- Price$173.8
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB3426
- Product descriptionVGX-1027
- Packaging10mg
- Price$125
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB3426
- Product descriptionVGX-1027
- Packaging50mg
- Price$468
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS605980
- Product descriptionVGX-1027
- Packaging50mg
- Price$225
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb546180
- Product descriptionVGX-1027 >98%
- Packaging5mg
- Price$136
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb546180
- Product descriptionVGX-1027 >98%
- Packaging25mg
- Price$307.7
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181345
- Product descriptionVGX-1027(GIT 27) >98%
- Packaging100mg
- Price$606.9
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181345
- Product descriptionVGX-1027(GIT 27) >98%
- Packaging250mg
- Price$912.9
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181345
- Product descriptionVGX-1027(GIT 27) >98%
- Packaging1000mg
- Price$2097.8
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number16293
- Product descriptionGIT 27 ≥98%
- Packaging5mg
- Price$62
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16293
- Product descriptionGIT 27 ≥98%
- Packaging10mg
- Price$109
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16293
- Product descriptionGIT 27 ≥98%
- Packaging25mg
- Price$239
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16293
- Product descriptionGIT 27 ≥98%
- Packaging50mg
- Price$419
- Updated2024-03-01
- Buy
- ManufacturerChem-Impex
- Product number38360
- Product descriptionVGX-1027,98%(HPLC) 98%(HPLC)
- Packaging10MG
- Price$145.6
- Updated2021-12-16
- Buy
- ManufacturerChem-Impex
- Product number38360
- Product descriptionVGX-1027,98%(HPLC) 98%(HPLC)
- Packaging50MG
- Price$577.92
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 2792AH | 4,5-Dihydro-3-phenyl-5-isoxazoleaceticacid | 1g | $959 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | CYT0000086 | GIT-27 95.00% | 5MG | $173.8 | 2021-12-16 | Buy |
ApexBio Technology | B3426 | VGX-1027 | 10mg | $125 | 2021-12-16 | Buy |
ApexBio Technology | B3426 | VGX-1027 | 50mg | $468 | 2021-12-16 | Buy |
Arctom | AS605980 | VGX-1027 | 50mg | $225 | 2021-12-16 | Buy |
Biorbyt Ltd | orb546180 | VGX-1027 >98% | 5mg | $136 | 2021-12-16 | Buy |
Biorbyt Ltd | orb546180 | VGX-1027 >98% | 25mg | $307.7 | 2021-12-16 | Buy |
Biorbyt Ltd | orb181345 | VGX-1027(GIT 27) >98% | 100mg | $606.9 | 2021-12-16 | Buy |
Biorbyt Ltd | orb181345 | VGX-1027(GIT 27) >98% | 250mg | $912.9 | 2021-12-16 | Buy |
Biorbyt Ltd | orb181345 | VGX-1027(GIT 27) >98% | 1000mg | $2097.8 | 2021-12-16 | Buy |
Cayman Chemical | 16293 | GIT 27 ≥98% | 5mg | $62 | 2024-03-01 | Buy |
Cayman Chemical | 16293 | GIT 27 ≥98% | 10mg | $109 | 2024-03-01 | Buy |
Cayman Chemical | 16293 | GIT 27 ≥98% | 25mg | $239 | 2024-03-01 | Buy |
Cayman Chemical | 16293 | GIT 27 ≥98% | 50mg | $419 | 2024-03-01 | Buy |
Chem-Impex | 38360 | VGX-1027,98%(HPLC) 98%(HPLC) | 10MG | $145.6 | 2021-12-16 | Buy |
Chem-Impex | 38360 | VGX-1027,98%(HPLC) 98%(HPLC) | 50MG | $577.92 | 2021-12-16 | Buy |
Properties
Melting point :157-158℃
storage temp. :Sealed in dry,2-8°C
solubility :Soluble in DMSO (up to 30 mg/ml).
form :solid
color :White
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
storage temp. :Sealed in dry,2-8°C
solubility :Soluble in DMSO (up to 30 mg/ml).
form :solid
color :White
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Safety Information
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Signal word: | Danger | |||||||||||||||||||||
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Precautionary statements: |
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Description
GIT 27 is an orally active, isoxazole compound that exhibits various immunomodulatory properties both in vitro and in preclinical in vivo models of autoimmune diseases by inhibiting inflammatory antigen presentation. It has been shown to target macrophages, reducing the production of the proinflammatory mediators TNF-α, IL-1β, macrophage migration inhibitory factor, and inducible nitric oxide synthase-mediated nitric oxide generation in both pancreatic islets and peripheral compartments. GIT 27 can also prevent IL-1β/interferon-γ-induced pancreatic islet death in vitro at 10 μg/ml and reduce the cumulative incidence of diabetes and insulitis in a mouse model of type 1 diabetes at 20 mg/kg.Related product price
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