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ChemicalBook >> CAS DataBase List >> 680C91

680C91

680C91 price.
  • $44 - $1329
  • Product name: 680C91
  • CAS: 163239-22-3
  • MF: C15H11FN2
  • MW: 238.26
  • EINECS:
  • MDL Number:MFCD20926361
  • Synonyms:680C91;1H-Indole, 6-fluoro-3-[(1E)-2-(3-pyridinyl)ethenyl]-;6-Fluoro-3-[(1E)-2-(3-pyridinyl)ethenyl)-1H-indole;680C91 >=98% (HPLC);6-fluoro-3-[(E)-2-(pyridin-3-yl)ethenyl]-1H-indole;inhibit,Inhibitor,680C91,tryptophan 2,3-dioxygenasetryptophan catabolismAlzheimer’s Disease,680C-91;(E)-6-fluoro-3-(2-(pyridin-3-yl)vinyl)-1H-indole
Price8 Properties Safety Information Description
8 prices
Selected condition：
Brand
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 2.5mg
  • 5mg
  • 10MG
  • 25mg
  • 50MG
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0001271
  • Product description6-FLUORO-3-[(1E)-2-(3-PYRIDINYL)ETHENYL]-1H-INDOLE 95.00%
  • Packaging10MG
  • Price$744.98
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0001271
  • Product description6-FLUORO-3-[(1E)-2-(3-PYRIDINYL)ETHENYL]-1H-INDOLE 95.00%
  • Packaging50MG
  • Price$1269.35
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5573
  • Product description680C91
  • Packaging10mg
  • Price$308
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5573
  • Product description680C91
  • Packaging50mg
  • Price$1329
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0287
  • Product description680C91 ≥98% (HPLC)
  • Packaging25mg
  • Price$441
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0287
  • Product description680C91 ≥98% (HPLC)
  • Packaging5mg
  • Price$44
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberF632063
  • Product description6-Fluoro-3-[(1E)-2-(3-pyridinyl)ethenyl]-1H-indole
  • Packaging2.5mg
  • Price$220
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number254445
  • Product description680C91
  • Packaging5mg
  • Price$389
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation INB0001271 6-FLUORO-3-[(1E)-2-(3-PYRIDINYL)ETHENYL]-1H-INDOLE 95.00% 10MG $744.98 2021-12-16 Buy
American Custom Chemicals Corporation INB0001271 6-FLUORO-3-[(1E)-2-(3-PYRIDINYL)ETHENYL]-1H-INDOLE 95.00% 50MG $1269.35 2021-12-16 Buy
ApexBio Technology B5573 680C91 10mg $308 2021-12-16 Buy
ApexBio Technology B5573 680C91 50mg $1329 2021-12-16 Buy
Sigma-Aldrich SML0287 680C91 ≥98% (HPLC) 25mg $441 2024-03-01 Buy
Sigma-Aldrich SML0287 680C91 ≥98% (HPLC) 5mg $44 2024-03-01 Buy
TRC F632063 6-Fluoro-3-[(1E)-2-(3-pyridinyl)ethenyl]-1H-indole 2.5mg $220 2021-12-16 Buy
Usbiological 254445 680C91 5mg $389 2021-12-16 Buy

Properties

Boiling point :431.2±35.0 °C(Predicted)
Density :1.305±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ≥10mg/mL
pka :15.92±0.30(Predicted)
form :powder
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger GHS hazard pictograms P280, P305+P351+P338, P310
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

680C91 (163239-22-3) is a potent and selective inhibitor of tryptophan 2,3-dioxygenase (TDO) Ki=42 nM).1,2?Displays no activity against indoleamine 2,3-dioxygenase, MAO-A and B and does not effect serotonin uptake. Elevates CSF tryptophan by up to 260% and CSF serotonin by 170% of basal.2?TDO inhibition by 680C91 in glioma cells blocked the release of kynurenine (Cat.# 10-2666), an endogenous tumor promoting AHR ligand.4

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