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ChemicalBook >> CAS DataBase List >> Benzamide, N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-4-chloro-

Benzamide, N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-4-chloro-

Benzamide, N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-4-chloro- price.
  • $45 - $440
  • Product name: Benzamide, N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-4-chloro-
  • CAS: 711085-63-1
  • MF: C14H17ClN2O
  • MW: 264.75
  • EINECS:
  • MDL Number:MFCD08703110
  • Synonyms:Benzamide, N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-4-chloro-;4-chloro-N-[(3R)-quinuclidin-3-yl]benzamide;PNU 282987 free base;N-[(3R)-1-azabicyclo[2.2.2]octan-3-yl]-4-chlorobenzamide;(R)-4-Chloro-N-(quinuclidin-3-yl)benzamide
7 prices
Selected condition:
Brand
  • AK Scientific
  • Cayman Chemical
  • TRC
Package
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • ManufacturerAK Scientific
  • Product number3040CR
  • Product descriptionBenzamide,N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-4-chloro-
  • Packaging10mg
  • Price$191
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number3040CR
  • Product descriptionBenzamide,N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-4-chloro-
  • Packaging50mg
  • Price$440
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number17424
  • Product descriptionPNU 282987 ≥98%
  • Packaging5mg
  • Price$45
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17424
  • Product descriptionPNU 282987 ≥98%
  • Packaging10mg
  • Price$85
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17424
  • Product descriptionPNU 282987 ≥98%
  • Packaging25mg
  • Price$166
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17424
  • Product descriptionPNU 282987 ≥98%
  • Packaging50mg
  • Price$308
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberP653463
  • Product descriptionPNU-282987
  • Packaging25mg
  • Price$140
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3040CR Benzamide,N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-4-chloro- 10mg $191 2021-12-16 Buy
AK Scientific 3040CR Benzamide,N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-4-chloro- 50mg $440 2021-12-16 Buy
Cayman Chemical 17424 PNU 282987 ≥98% 5mg $45 2024-03-01 Buy
Cayman Chemical 17424 PNU 282987 ≥98% 10mg $85 2024-03-01 Buy
Cayman Chemical 17424 PNU 282987 ≥98% 25mg $166 2024-03-01 Buy
Cayman Chemical 17424 PNU 282987 ≥98% 50mg $308 2024-03-01 Buy
TRC P653463 PNU-282987 25mg $140 2021-12-16 Buy

Properties

Boiling point :431.5±30.0 °C(Predicted)
Density :1.27±0.1 g/cm3(Predicted)
solubility :DMF: 10 mg/ml; DMSO: 30 mg/ml; Ethanol: 20 mg/ml; PBS (pH 7.2): 5 mg/ml
form :A crystalline solid
pka :13.86±0.20(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

PNU-282987 is a highly selective α7 nicotinic acetylcholine receptor agonist (1,2). PNU-282,987 has been utilized to generate retinal neurons in the absence of retinal injury or exogenous growth factors in rat (1). PNU-282,987 has the potential to reverse vision loss due to neurodegenerative disease or aging.

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