N-(4-Acetyl-4,5-dihydro-5-methyl-5-phenyl-1,3,4-thiadiazol-2-yl)acetamide
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- $32 - $1600
- Product name: N-(4-Acetyl-4,5-dihydro-5-methyl-5-phenyl-1,3,4-thiadiazol-2-yl)acetamide
- CAS: 72926-24-0
- MF: C13H15N3O2S
- MW: 277.34
- EINECS:
- MDL Number:MFCD00181155
- Synonyms:K 858;N-(4-Acetyl-4,5-dihydro-5-methyl-5-phenyl-1,3,4-thiadiazol-2-yl)acetamide;N-(4-acetyl-5-methyl-5-phenyl-4,5-dihydro-1,3,4-thiadiazol-2-yl)a Cetamide;K858;K-858;K858 (Racemic);Acetamide, N-(4-acetyl-4,5-dihydro-5-methyl-5-phenyl-1,3,4-thiadiazol-2-yl)-;inhibit,Inhibitor,K858 (Racemic),Apoptosis,K-858 (Racemic),Kinesin
39 prices
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Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 50
- 10
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 1G
- 2.5G
- 5G
- ManufacturerAK Scientific
- Product number9996AF
- Product descriptionN-(4-Acetyl-4,5-dihydro-5-methyl-5-phenyl-1,3,4-thiadiazol-2-yl)acetamide
- Packaging5mg
- Price$124
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number9996AF
- Product descriptionN-(4-Acetyl-4,5-dihydro-5-methyl-5-phenyl-1,3,4-thiadiazol-2-yl)acetamide
- Packaging10mg
- Price$184
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number9996AF
- Product descriptionN-(4-Acetyl-4,5-dihydro-5-methyl-5-phenyl-1,3,4-thiadiazol-2-yl)acetamide
- Packaging100mg
- Price$945
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA394288
- Product descriptionK 858 98+%
- Packaging5mg
- Price$111
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA394288
- Product descriptionK 858 98+%
- Packaging10mg
- Price$166
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA394288
- Product descriptionK 858 98+%
- Packaging25mg
- Price$248
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA394288
- Product descriptionK 858 98+%
- Packaging50mg
- Price$346
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA394288
- Product descriptionK 858 98+%
- Packaging100mg
- Price$519
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCHM0123024
- Product descriptionN-(4-ACETYL-5-METHYL-5-PHENYL-4,5-DIHYDRO-1,3,4-THIADIAZOL-2-YL)ACETAMIDE 95.00%
- Packaging1G
- Price$721.57
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCHM0123024
- Product descriptionN-(4-ACETYL-5-METHYL-5-PHENYL-4,5-DIHYDRO-1,3,4-THIADIAZOL-2-YL)ACETAMIDE 95.00%
- Packaging2.5G
- Price$983.88
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCHM0123024
- Product descriptionN-(4-ACETYL-5-METHYL-5-PHENYL-4,5-DIHYDRO-1,3,4-THIADIAZOL-2-YL)ACETAMIDE 95.00%
- Packaging5G
- Price$1168.42
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7480
- Product descriptionK 858
- Packaging5mg
- Price$79
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7480
- Product descriptionK 858
- Packaging10mg
- Price$142
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7480
- Product descriptionK 858
- Packaging25mg
- Price$308
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7480
- Product descriptionK 858
- Packaging50mg
- Price$551
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7480
- Product descriptionK 858
- Packaging100mg
- Price$1008
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 9996AF | N-(4-Acetyl-4,5-dihydro-5-methyl-5-phenyl-1,3,4-thiadiazol-2-yl)acetamide | 5mg | $124 | 2021-12-16 | Buy |
| AK Scientific | 9996AF | N-(4-Acetyl-4,5-dihydro-5-methyl-5-phenyl-1,3,4-thiadiazol-2-yl)acetamide | 10mg | $184 | 2021-12-16 | Buy |
| AK Scientific | 9996AF | N-(4-Acetyl-4,5-dihydro-5-methyl-5-phenyl-1,3,4-thiadiazol-2-yl)acetamide | 100mg | $945 | 2021-12-16 | Buy |
| Ambeed | A394288 | K 858 98+% | 5mg | $111 | 2021-12-16 | Buy |
| Ambeed | A394288 | K 858 98+% | 10mg | $166 | 2021-12-16 | Buy |
| Ambeed | A394288 | K 858 98+% | 25mg | $248 | 2021-12-16 | Buy |
| Ambeed | A394288 | K 858 98+% | 50mg | $346 | 2021-12-16 | Buy |
| Ambeed | A394288 | K 858 98+% | 100mg | $519 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0123024 | N-(4-ACETYL-5-METHYL-5-PHENYL-4,5-DIHYDRO-1,3,4-THIADIAZOL-2-YL)ACETAMIDE 95.00% | 1G | $721.57 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0123024 | N-(4-ACETYL-5-METHYL-5-PHENYL-4,5-DIHYDRO-1,3,4-THIADIAZOL-2-YL)ACETAMIDE 95.00% | 2.5G | $983.88 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0123024 | N-(4-ACETYL-5-METHYL-5-PHENYL-4,5-DIHYDRO-1,3,4-THIADIAZOL-2-YL)ACETAMIDE 95.00% | 5G | $1168.42 | 2021-12-16 | Buy |
| ApexBio Technology | B7480 | K 858 | 5mg | $79 | 2021-12-16 | Buy |
| ApexBio Technology | B7480 | K 858 | 10mg | $142 | 2021-12-16 | Buy |
| ApexBio Technology | B7480 | K 858 | 25mg | $308 | 2021-12-16 | Buy |
| ApexBio Technology | B7480 | K 858 | 50mg | $551 | 2021-12-16 | Buy |
| ApexBio Technology | B7480 | K 858 | 100mg | $1008 | 2021-12-16 | Buy |
Properties
Melting point :216-217 °C(Solv: ethanol (64-17-5))
Density :1.27±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,Room Temperature
solubility :DMSO: ≥20mg/mL
pka :8.61±0.40(Predicted)
form :powder
color :white to off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
Density :1.27±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,Room Temperature
solubility :DMSO: ≥20mg/mL
pka :8.61±0.40(Predicted)
form :powder
color :white to off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
Safety Information
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Description
K858 (72926-24-0) is a selective mitotic kinesin Eg5 inhibitor (IC50 = 1.3 μM) which acts in an ATP-noncompetitive manner.1,2?It is at least 150-fold more selective for Eg5 than other members of the kinesin superfamily. K-858 blocks centrosome separation, activates the spindle checkpoint and induces mitotic arrest accompanied by the formation of monopolar spindles. Displays no effect on microtubule polymerization. Selectively displays antiproliferative effects via induction of mitotic cell death in cancer cells over nontransformed cells.1Related product price
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Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
TargetMol Chemicals Inc.
ShenZhen Trendseen Biological Technology Co.,Ltd.
Aladdin Scientific
Amadis Chemical Company Limited
