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ChemicalBook >> CAS DataBase List >> 2-(4-PIPERAZINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE DIHYDROCHLORIDE

2-(4-PIPERAZINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE DIHYDROCHLORIDE

2-(4-PIPERAZINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE DIHYDROCHLORIDE price.
3 prices
Selected condition:
Brand
  • AK Scientific
  • Cayman Chemical
Package
  • 1mg
  • 5mg
  • ManufacturerAK Scientific
  • Product number5473DW
  • Product description2-(4-Piperazinyl)-8-phenyl-4h-1-benzopyran-4-onedihydrochloride
  • Packaging1mg
  • Price$149
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number15514
  • Product descriptionLY303511 (hydrochloride) ≥98%
  • Packaging1mg
  • Price$47
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15514
  • Product descriptionLY303511 (hydrochloride) ≥98%
  • Packaging5mg
  • Price$160
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 5473DW 2-(4-Piperazinyl)-8-phenyl-4h-1-benzopyran-4-onedihydrochloride 1mg $149 2021-12-16 Buy
Cayman Chemical 15514 LY303511 (hydrochloride) ≥98% 1mg $47 2024-03-01 Buy
Cayman Chemical 15514 LY303511 (hydrochloride) ≥98% 5mg $160 2024-03-01 Buy

Properties

storage temp. :Store at -20°C
solubility :DMF: 5 mg/ml; DMSO: 20 mg/ml; Ethanol: 1 mg/ml; PBS (pH 7.2): 0.1 mg/ml
form :A solid

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

LY303511 is a close structural analog of LY294002 , a selective phosphatidylinositol 3-kinase (PI3K) inhibitor.1 LY303511, however, does not inhibit PI3K-dependent phosphorylation of Akt but instead has been shown to inhibit mTOR-dependent phosphorylation of S6K.1 It can reduce cell proliferation in human lung epithelial adenocarcinoma cells, blocking G2/M progression and inhibiting casein kinase 2 activity.1 LY303511 demonstrates tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) sensitizing activity in HeLa cells that are refractory to TRAIL-induced apoptosis.2 LY303511 is also reported to block voltage-gated potassium (Kv) channels.3