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ChemicalBook >> CAS DataBase List >> Palmitoleoyl 3-carbacyclic Phosphatidic Acid

Palmitoleoyl 3-carbacyclic Phosphatidic Acid

Palmitoleoyl 3-carbacyclic Phosphatidic Acid price.
  • $76 - $1037
  • Product name: Palmitoleoyl 3-carbacyclic Phosphatidic Acid
  • CAS: 910228-13-6
  • MF: C20H37O5P
  • MW: 388.48
  • EINECS:
  • MDL Number:MFCD18427963
  • Synonyms:Palmitoleoyl 3-carbacyclic Phosphatidic Acid;IAGUMCXYAAGWJD-FPLPWBNLSA-N;Palmitoleoyl 3-carbacyclic Phosphatidic Acid Exclusive;9-Hexadecenoic acid, (2-hydroxy-2-oxido-1,2-oxaphospholan-5-yl)methyl ester, (9Z)-
6 prices
Selected condition:
Brand
  • AK Scientific
  • Cayman Chemical
Package
  • 500μg
  • 1mg
  • 5mg
  • 10mg
  • ManufacturerAK Scientific
  • Product number1067AH
  • Product description(2-Hydroxy-2-oxido-1,2-oxaphospholan-5-yl)methylester-9Z-9Cl-9-hexadecenoicacid
  • Packaging1mg
  • Price$256
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number1067AH
  • Product description(2-Hydroxy-2-oxido-1,2-oxaphospholan-5-yl)methylester-9Z-9Cl-9-hexadecenoicacid
  • Packaging5mg
  • Price$758
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10010298
  • Product descriptionPalmitoleoyl 3-carbacyclic Phosphatidic Acid ≥95%
  • Packaging500μg
  • Price$76
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10010298
  • Product descriptionPalmitoleoyl 3-carbacyclic Phosphatidic Acid ≥95%
  • Packaging1mg
  • Price$142
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10010298
  • Product descriptionPalmitoleoyl 3-carbacyclic Phosphatidic Acid ≥95%
  • Packaging5mg
  • Price$593
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10010298
  • Product descriptionPalmitoleoyl 3-carbacyclic Phosphatidic Acid ≥95%
  • Packaging10mg
  • Price$1037
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1067AH (2-Hydroxy-2-oxido-1,2-oxaphospholan-5-yl)methylester-9Z-9Cl-9-hexadecenoicacid 1mg $256 2021-12-16 Buy
AK Scientific 1067AH (2-Hydroxy-2-oxido-1,2-oxaphospholan-5-yl)methylester-9Z-9Cl-9-hexadecenoicacid 5mg $758 2021-12-16 Buy
Cayman Chemical 10010298 Palmitoleoyl 3-carbacyclic Phosphatidic Acid ≥95% 500μg $76 2024-03-01 Buy
Cayman Chemical 10010298 Palmitoleoyl 3-carbacyclic Phosphatidic Acid ≥95% 1mg $142 2024-03-01 Buy
Cayman Chemical 10010298 Palmitoleoyl 3-carbacyclic Phosphatidic Acid ≥95% 5mg $593 2024-03-01 Buy
Cayman Chemical 10010298 Palmitoleoyl 3-carbacyclic Phosphatidic Acid ≥95% 10mg $1037 2024-03-01 Buy

Properties

solubility :PBS (pH 7.2): 5 mg/ml

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H310 Fatal in contact with skin Acute toxicity,dermal Category 1, 2 Danger GHS hazard pictograms P262, P264, P270, P280, P302+P350,P310, P322, P361, P363, P405, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H331 Toxic if inhaled Acute toxicity,inhalation Category 3 Danger GHS hazard pictograms P261, P271, P304+P340, P311, P321,P403+P233, P405, P501
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H372 Causes damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P314, P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P262 Do not get in eyes, on skin, or on clothing.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P310 Immediately call a POISON CENTER or doctor/physician.
P314 Get medical advice/attention if you feel unwell.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P370+P378 In case of fire: Use … for extinction.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P403+P235 Store in a well-ventilated place. Keep cool.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Cyclic phosphatidic acids (cPAs) are naturally occurring analogs of lysophosphatidic acid (LPA) in which the sn-2 hydroxy group forms a 5-membered ring with the sn-3 phosphate.1,2 Carba-derivatives of cPA (ccPA) are modified at the sn-2 (2-ccPA) or sn-3 (3-ccPA) linkage, preventing the opening of cPA to produce lysophosphatidic acid (LPA).3 Palmitoleoyl 3-carbacyclic phosphatidic acid (3-ccPA 16:1) is a cyclic LPA analog that contains the 16:1 fatty acid, palmitoleate, at the sn-1 position of the glycerol backbone.3 At 25 μM, it inhibits the transcellular migration of MM1 cells across mesothelial cell monolayers in response to fetal bovine serum (86.9%) or LPA (99.9%) without affecting proliferation.3 3-ccPA 16:1 significantly inhibits autotaxin (IC50 = 620 nM),4 an enzyme that is important in cancer cell survival, growth, migration, invasion and metastasis. When delivered intraperitoneally, 3-ccPA 16:1 significantly reduces the number of lung metastases formed in mice injected with B16F10 melanoma cells in the tail vein.4