3-(3-(pyridin-3-yl)-1,2,4-oxadiazol-5-yl)benzonitrile
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- $32 - $2275
- Product name: 3-(3-(pyridin-3-yl)-1,2,4-oxadiazol-5-yl)benzonitrile
- CAS: 913830-15-6
- MF: C14H8N4O
- MW: 248.24
- EINECS:-0
- MDL Number:MFCD26390306
- Synonyms:3-(3-(pyridin-3-yl)-1,2,4-oxadiazol-5-yl)benzonitrile;NS 9283;3-[3-(3-Pyridinyl)-1,2,4-oxadiazol-5-yl]benzonitrile;NS 9283;NS-9283;NS9283;NS-9283;NS9283;Benzonitrile, 3-[3-(3-pyridinyl)-1,2,4-oxadiazol-5-yl]-;NS9283,Inhibitor,Nicotinic acetylcholine receptors,nAChR,inhibit
15 prices
Selected condition：
Brand
- AK Scientific
- Cayman Chemical
- DC Chemicals
- Medical Isotopes, Inc.
- Tocris
- TRC
- Usbiological
Package
- 50
- 5mg
- 1mg
- 10
- 10mg
- 25mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number2045CT
- Product description3-(3-(Pyridin-3-yl)-1,2,4-oxadiazol-5-yl)benzonitrile
- Packaging10mg
- Price$302
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2045CT
- Product description3-(3-(Pyridin-3-yl)-1,2,4-oxadiazol-5-yl)benzonitrile
- Packaging25mg
- Price$564
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number29189
- Product descriptionNS 9283
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29189
- Product descriptionNS 9283
- Packaging5mg
- Price$122
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29189
- Product descriptionNS 9283
- Packaging10mg
- Price$184
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29189
- Product descriptionNS 9283
- Packaging25mg
- Price$420
- Updated2024-03-01
- Buy
- ManufacturerDC Chemicals
- Product numberDC8783
- Product descriptionNS9283 >98%
- Packaging100mg
- Price$350
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC8783
- Product descriptionNS9283 >98%
- Packaging250mg
- Price$600
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC8783
- Product descriptionNS9283 >98%
- Packaging1g
- Price$1300
- Updated2021-12-16
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number60805
- Product descriptionNS9283
- Packaging100mg
- Price$2275
- Updated2021-12-16
- Buy
- ManufacturerTocris
- Product number5112
- Product descriptionNS9283 ≥99%(HPLC)
- Packaging10
- Price$201
- Updated2021-12-16
- Buy
- ManufacturerTocris
- Product number5112
- Product descriptionNS9283 ≥99%(HPLC)
- Packaging50
- Price$844
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberN900260
- Product descriptionNS9283
- Packaging5mg
- Price$115
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number460989
- Product descriptionNS 9283
- Packaging5mg
- Price$403
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number256048
- Product descriptionNS 9283
- Packaging10mg
- Price$452
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 2045CT | 3-(3-(Pyridin-3-yl)-1,2,4-oxadiazol-5-yl)benzonitrile | 10mg | $302 | 2021-12-16 | Buy |
| AK Scientific | 2045CT | 3-(3-(Pyridin-3-yl)-1,2,4-oxadiazol-5-yl)benzonitrile | 25mg | $564 | 2021-12-16 | Buy |
| Cayman Chemical | 29189 | NS 9283 | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 29189 | NS 9283 | 5mg | $122 | 2024-03-01 | Buy |
| Cayman Chemical | 29189 | NS 9283 | 10mg | $184 | 2024-03-01 | Buy |
| Cayman Chemical | 29189 | NS 9283 | 25mg | $420 | 2024-03-01 | Buy |
| DC Chemicals | DC8783 | NS9283 >98% | 100mg | $350 | 2021-12-16 | Buy |
| DC Chemicals | DC8783 | NS9283 >98% | 250mg | $600 | 2021-12-16 | Buy |
| DC Chemicals | DC8783 | NS9283 >98% | 1g | $1300 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 60805 | NS9283 | 100mg | $2275 | 2021-12-16 | Buy |
| Tocris | 5112 | NS9283 ≥99%(HPLC) | 10 | $201 | 2021-12-16 | Buy |
| Tocris | 5112 | NS9283 ≥99%(HPLC) | 50 | $844 | 2021-12-16 | Buy |
| TRC | N900260 | NS9283 | 5mg | $115 | 2021-12-16 | Buy |
| Usbiological | 460989 | NS 9283 | 5mg | $403 | 2021-12-16 | Buy |
| Usbiological | 256048 | NS 9283 | 10mg | $452 | 2021-12-16 | Buy |
Properties
Boiling point :469.9±55.0 °C(Predicted)
Density :1.37±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 10 mg/ml; DMF:PBS (pH 7.2) (1:1): 0.5 mg/ml; DMSO: 3 mg/ml; Ethanol: Partially soluble
form :A crystalline solid
pka :1.40±0.12(Predicted)
color :White to off-white
Density :1.37±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 10 mg/ml; DMF:PBS (pH 7.2) (1:1): 0.5 mg/ml; DMSO: 3 mg/ml; Ethanol: Partially soluble
form :A crystalline solid
pka :1.40±0.12(Predicted)
color :White to off-white
Safety Information
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Description
NS 9283 is a positive allosteric modulator of α4β2 subunit-containing nicotinic acetylcholine receptors (nAChRs) that potentiates ACh-induced currents in HEK293 cells expressing human α4β2 subunit-containing nAChRs (EC50 = 4 μM). In vivo, NS 9283 potentiates ABT-594 analgesic efficacy in rat models of carrageenan-induced thermal hyperalgesia, paw skin incision post-operative pain, and monoiodoacetate-induced osteoarthritis. It reduces nicotine, but not sucrose, self-administration and reinstatement in rats when administered at a dose of 3.5 mg/kg.Suppliers and manufacturers
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