N,N'-(Dithiodi-2,1-ethanediyl)bis[2,5-dichloro-benzenesulfonaMide
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- $46.5 - $1050
- Product name: N,N'-(Dithiodi-2,1-ethanediyl)bis[2,5-dichloro-benzenesulfonaMide
- CAS: 927822-86-4
- MF: C16H16Cl4N2O4S4
- MW: 570.38
- EINECS:
- MDL Number:MFCD22683809
- Synonyms:N,N'-(Dithiodi-2,1-ethanediyl)bis[2,5-dichloro-benzenesulfonaMide;KC7F2;N,N'-(2,2'-disulfanediylbis(ethane-2,1-diyl))bis(2,5-dichlorobenzenesulfonamide);N,N'-(Disulfanediylbis(ethane-2,1-diyl))bis(2,5-dichlorobenzenesulfonamide);HIF-1α Translation Inhibitor, KC7F2 ;Benzenesulfonamide, N,N'-(dithiodi-2,1-ethanediyl)bis[2,5-dichloro-;KC7F2, >98%;HIF-1α Translation Inhibitor, KC7F2 - CAS 927822-86-4 - Calbiochem
28 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- ApexBio Technology
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 50
- 1mg
- 10
- 5mg
- 10mg
- 25mg
- 50mg
- 250mg
- 10mM(in 1mL DMSO)
- 100mg
- ManufacturerAK Scientific
- Product number2122CW
- Product descriptionKC7f2
- Packaging10mg
- Price$197
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA261687
- Product descriptionKC7F2 98+%
- Packaging5mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA261687
- Product descriptionKC7F2 98+%
- Packaging10mg
- Price$155
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA261687
- Product descriptionKC7F2 98+%
- Packaging25mg
- Price$201
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA261687
- Product descriptionKC7F2 98+%
- Packaging50mg
- Price$261
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA261687
- Product descriptionKC7F2 98+%
- Packaging100mg
- Price$339
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4507
- Product descriptionKC7F2
- Packaging10mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4507
- Product descriptionKC7F2
- Packaging10mM(in 1mL DMSO)
- Price$63
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4507
- Product descriptionKC7F2
- Packaging50mg
- Price$200
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb546246
- Product descriptionKC7F2 >98%
- Packaging10mg
- Price$173.4
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb546246
- Product descriptionKC7F2 >98%
- Packaging50mg
- Price$447.1
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number14123
- Product descriptionKC7F2 ≥98%
- Packaging5mg
- Price$57
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14123
- Product descriptionKC7F2 ≥98%
- Packaging10mg
- Price$89
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14123
- Product descriptionKC7F2 ≥98%
- Packaging50mg
- Price$330
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-5069
- Product descriptionKC7F2 ≥99.0%
- Packaging5mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5069
- Product descriptionKC7F2 ≥99.0%
- Packaging10mg
- Price$60
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 2122CW | KC7f2 | 10mg | $197 | 2021-12-16 | Buy |
| Ambeed | A261687 | KC7F2 98+% | 5mg | $120 | 2021-12-16 | Buy |
| Ambeed | A261687 | KC7F2 98+% | 10mg | $155 | 2021-12-16 | Buy |
| Ambeed | A261687 | KC7F2 98+% | 25mg | $201 | 2021-12-16 | Buy |
| Ambeed | A261687 | KC7F2 98+% | 50mg | $261 | 2021-12-16 | Buy |
| Ambeed | A261687 | KC7F2 98+% | 100mg | $339 | 2021-12-16 | Buy |
| ApexBio Technology | A4507 | KC7F2 | 10mg | $50 | 2021-12-16 | Buy |
| ApexBio Technology | A4507 | KC7F2 | 10mM(in 1mL DMSO) | $63 | 2021-12-16 | Buy |
| ApexBio Technology | A4507 | KC7F2 | 50mg | $200 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb546246 | KC7F2 >98% | 10mg | $173.4 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb546246 | KC7F2 >98% | 50mg | $447.1 | 2021-12-16 | Buy |
| Cayman Chemical | 14123 | KC7F2 ≥98% | 5mg | $57 | 2024-03-01 | Buy |
| Cayman Chemical | 14123 | KC7F2 ≥98% | 10mg | $89 | 2024-03-01 | Buy |
| Cayman Chemical | 14123 | KC7F2 ≥98% | 50mg | $330 | 2024-03-01 | Buy |
| ChemScene | CS-5069 | KC7F2 ≥99.0% | 5mg | $50 | 2021-12-16 | Buy |
| ChemScene | CS-5069 | KC7F2 ≥99.0% | 10mg | $60 | 2021-12-16 | Buy |
Properties
Boiling point :708.8±70.0 °C(Predicted)
Density :1.583±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: soluble20mg/mL, clear
form :powder
pka :9.26±0.50(Predicted)
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
Density :1.583±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: soluble20mg/mL, clear
form :powder
pka :9.26±0.50(Predicted)
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
Safety Information
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Description
Hypoxia-inducible factor-1 (HIF-1) is a heterodimeric transcription factor composed of a HIF-1α subunit and HIF-1β subunit. The HIF-1α subunit is regulated by cellular oxygen levels and therefore plays an important role in maintaining cellular oxygen homeostasis. KC7F2 is an inhibitor of HIF-1α protein translation, but not transcription, that suppresses phosphorylation of two key regulators of protein synthesis, eukaryotic translation initiation factor 4E binding protein 1 (4EBP1) and p70 S6 kinase (S6K). It inhibits hypoxia-induced expression of several HIF target genes, such as carbonic anhydrase IX, matrix metalloproteinase 2, enolase 1, and endothelin 1. KC7F2 is cytotoxic to a variety of cancer cell lines with an IC50 value of 15-25 μM.Related product price
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