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ChemicalBook >> CAS DataBase List >> (E)-C-HDMAPP (ammonium salt)

(E)-C-HDMAPP (ammonium salt)

(E)-C-HDMAPP (ammonium salt) price.
  • $76 - $982
  • Product name: (E)-C-HDMAPP (ammonium salt)
  • CAS: 933030-60-5
  • MF: C6H17NO7P2
  • MW: 277.15
  • EINECS:
  • MDL Number:MFCD18428007
  • Synonyms:(E)-C-HDMAPP (ammonium salt);triazanium:[(E)-5-hydroxy-4-methylpent-3-enyl]-phosphonatooxyphosphinate;(E)-C-HDMAPP (ammonium salt) Exclusive
6 prices
Selected condition:
Brand
  • AK Scientific
  • Cayman Chemical
Package
  • 500μg
  • 1mg
  • 5mg
  • 10mg
  • ManufacturerAK Scientific
  • Product number1973AH
  • Product descriptionP-[(3E)-5-Hydroxy-4-methyl-3-penten-1-yl]-isohypophosphoricacid,triammoniumsalt
  • Packaging1mg
  • Price$256
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number1973AH
  • Product descriptionP-[(3E)-5-Hydroxy-4-methyl-3-penten-1-yl]-isohypophosphoricacid,triammoniumsalt
  • Packaging5mg
  • Price$758
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number13151
  • Product description(E)-C-HDMAPP (ammonium salt) ≥95%
  • Packaging500μg
  • Price$76
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13151
  • Product description(E)-C-HDMAPP (ammonium salt) ≥95%
  • Packaging1mg
  • Price$144
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13151
  • Product description(E)-C-HDMAPP (ammonium salt) ≥95%
  • Packaging5mg
  • Price$604
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13151
  • Product description(E)-C-HDMAPP (ammonium salt) ≥95%
  • Packaging10mg
  • Price$982
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1973AH P-[(3E)-5-Hydroxy-4-methyl-3-penten-1-yl]-isohypophosphoricacid,triammoniumsalt 1mg $256 2021-12-16 Buy
AK Scientific 1973AH P-[(3E)-5-Hydroxy-4-methyl-3-penten-1-yl]-isohypophosphoricacid,triammoniumsalt 5mg $758 2021-12-16 Buy
Cayman Chemical 13151 (E)-C-HDMAPP (ammonium salt) ≥95% 500μg $76 2024-03-01 Buy
Cayman Chemical 13151 (E)-C-HDMAPP (ammonium salt) ≥95% 1mg $144 2024-03-01 Buy
Cayman Chemical 13151 (E)-C-HDMAPP (ammonium salt) ≥95% 5mg $604 2024-03-01 Buy
Cayman Chemical 13151 (E)-C-HDMAPP (ammonium salt) ≥95% 10mg $982 2024-03-01 Buy

Properties

storage temp. :Store at -20°C
solubility :PBS (pH 7.2): 10 mg/ml
form :A crystalline solid

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Synthetic and natural alkyl phosphates, also known as phosphoantigens, stimulate the proliferation of γδ-T lymphocytes. Isopentenyl pyrophosphate, and related derivatives including (E)-hydroxy-dimethyl-allyl pyrophosphate ((E)-HDMAPP), are particularly effective activators of γδ-T cells. (E)-C-HDMAPP is the pyrophosphonate form of (E)-HDMAPP. The pyrophosphonate moiety in (E)-C-HDMAPP is much less susceptible to chemical or enzymatic hydrolysis than its pyrophosphate counterpart. As a result, (E)-C-HDMAPP is much more stable in solution and in vascular circulation. (E)-C-HDMAPP possesses comparable activity to (E)-HDMAPP, which is the most potent of the isoprenoid phosphoantigens. (E)-C-HDMAPP stimulates the synthesis of tumor necrosis factor (TNF-α) by γδ-T lymphocytes with an IC50 value of 0.91 nM. (E)-C-HDMAPP also significantly increases the number of circulating γδ-T cells in vivo, in cynomolgus monkeys.