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ChemicalBook >> CAS DataBase List >> BenzaMide, N-[3-[3-[4-[(diMethylaMino)Methyl]phenyl]pyrazolo[1,5-a]pyriMidin-7-yl]phenyl]-3-(trifluoroMethyl)-

BenzaMide, N-[3-[3-[4-[(diMethylaMino)Methyl]phenyl]pyrazolo[1,5-a]pyriMidin-7-yl]phenyl]-3-(trifluoroMethyl)-

$62 - $1800
Product name: BenzaMide, N-[3-[3-[4-[(diMethylaMino)Methyl]phenyl]pyrazolo[1,5-a]pyriMidin-7-yl]phenyl]-3-(trifluoroMethyl)-
CAS: 950736-05-7
MF: C29H24F3N5O
MW: 515.53
EINECS:
MDL Number:MFCD25977055
Synonyms:BenzaMide, N-[3-[3-[4-[(diMethylaMino)Methyl]phenyl]pyrazolo[1,5-a]pyriMidin-7-yl]phenyl]-3-(trifluoroMethyl)-;B-Raf IN 1;N-(3-(3-(4-((diMethylaMino)Methyl)phenyl)pyrazolo[1,5-a]pyriMidin-7-yl)phenyl)-3-(trifluoroMethyl)benzaMide;B-Raf IN 1, >=98%;B-Raf inhibit 1;MDK36057;RAF-IN-10n;CS-1184

Price20 Properties Safety Information Description

20 prices

Selected condition：

Brand

AK Scientific
ApexBio Technology
Apolloscientific
Cayman Chemical
ChemScene
Crysdot
DC Chemicals
TRC

Package

1mg
2mg
5mg
10mg
25mg
50mg
100mg
1g

ManufacturerAK Scientific
Product number3507AH
Product descriptionB-RAFIN1
Packaging5mg
Price$398
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberB4727
Product descriptionB-RafIN1
Packaging2mg
Price$302
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberB4727
Product descriptionB-RafIN1
Packaging5mg
Price$454
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberB4727
Product descriptionB-RafIN1
Packaging10mg
Price$662
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberB4727
Product descriptionB-RafIN1
Packaging50mg
Price$1796
Updated2021-12-16
Buy

ManufacturerApolloscientific
Product numberBISN0272
Product descriptionB-rafin1
Packaging1mg
Price$145
Updated2021-12-16
Buy

ManufacturerApolloscientific
Product numberBISN0272
Product descriptionB-rafin1
Packaging5mg
Price$334
Updated2021-12-16
Buy

ManufacturerApolloscientific
Product numberBISN0272
Product descriptionB-rafin1
Packaging10mg
Price$508
Updated2021-12-16
Buy

ManufacturerCayman Chemical
Product number23434
Product descriptionB-Raf Inhibitor 1 ≥98%
Packaging1mg
Price$62
Updated2024-03-01
Buy

ManufacturerCayman Chemical
Product number23434
Product descriptionB-Raf Inhibitor 1 ≥98%
Packaging5mg
Price$270
Updated2024-03-01
Buy

ManufacturerCayman Chemical
Product number23434
Product descriptionB-Raf Inhibitor 1 ≥98%
Packaging10mg
Price$477
Updated2024-03-01
Buy

ManufacturerCayman Chemical
Product number23434
Product descriptionB-Raf Inhibitor 1 ≥98%
Packaging25mg
Price$965
Updated2024-03-01
Buy

ManufacturerChemScene
Product numberCS-3238
Product descriptionB-RafIN1 98.66%
Packaging5mg
Price$288
Updated2021-12-16
Buy

ManufacturerChemScene
Product numberCS-3238
Product descriptionB-RafIN1 98.66%
Packaging50mg
Price$1140
Updated2021-12-16
Buy

ManufacturerChemScene
Product numberCS-3238
Product descriptionB-RafIN1 98.66%
Packaging100mg
Price$1800
Updated2021-12-16
Buy

ManufacturerCrysdot
Product numberCD31000106
Product descriptionB-RafIN1 98+%
Packaging50mg
Price$201
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
AK Scientific	3507AH	B-RAFIN1	5mg	$398	2021-12-16	Buy
ApexBio Technology	B4727	B-RafIN1	2mg	$302	2021-12-16	Buy
ApexBio Technology	B4727	B-RafIN1	5mg	$454	2021-12-16	Buy
ApexBio Technology	B4727	B-RafIN1	10mg	$662	2021-12-16	Buy
ApexBio Technology	B4727	B-RafIN1	50mg	$1796	2021-12-16	Buy
Apolloscientific	BISN0272	B-rafin1	1mg	$145	2021-12-16	Buy
Apolloscientific	BISN0272	B-rafin1	5mg	$334	2021-12-16	Buy
Apolloscientific	BISN0272	B-rafin1	10mg	$508	2021-12-16	Buy
Cayman Chemical	23434	B-Raf Inhibitor 1 ≥98%	1mg	$62	2024-03-01	Buy
Cayman Chemical	23434	B-Raf Inhibitor 1 ≥98%	5mg	$270	2024-03-01	Buy
Cayman Chemical	23434	B-Raf Inhibitor 1 ≥98%	10mg	$477	2024-03-01	Buy
Cayman Chemical	23434	B-Raf Inhibitor 1 ≥98%	25mg	$965	2024-03-01	Buy
ChemScene	CS-3238	B-RafIN1 98.66%	5mg	$288	2021-12-16	Buy
ChemScene	CS-3238	B-RafIN1 98.66%	50mg	$1140	2021-12-16	Buy
ChemScene	CS-3238	B-RafIN1 98.66%	100mg	$1800	2021-12-16	Buy
Crysdot	CD31000106	B-RafIN1 98+%	50mg	$201	2021-12-16	Buy

Next Last

Properties

Density :1.28±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 14 mg/ml; DMSO: 33 mg/ml; Ethanol: 1 mg/ml
pka :12.75±0.70(Predicted)
form :Powder
color :Light yellow to yellow

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	Pictogram	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning		P264, P270, P301+P312, P330, P501

Precautionary statements:

P280	Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

B-RAF IN 1 is an inhibitor of B-RAF (IC₅₀ = 24 nM) that also inhibits C-RAF (IC₅₀ = 25 nM). It is selective over 13 other kinases, including PKCα, IKKβ, and PI3Kα, at concentrations greater than 2 μM, but does inhibit p38α and CAMKII (IC₅₀s = 216 and 822 nM, respectively). B-RAF IN 1 binds to B-RAF in the inactive conformation based on co-crystallization with the wild-type enzyme. It inhibits proliferation of WM 266-4 and HT29 cells with IC₅₀ values of 920 and 780 nM, respectively.

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Suppliers and manufacturers

career henan chemical co

$3.00 /1KG
BenzaMide, N-[3-[3-[4-[(diMethylaMino)Methyl]phenyl]pyrazolo[1,5-a]pyriMidin-7-yl]phenyl]-3-(trifluoroMethyl)- CAS:950736-05-7

ATK CHEMICAL COMPANY LIMITED

TargetMol Chemicals Inc.

InvivoChem

ShenZhen Trendseen Biological Technology Co.,Ltd.

Aladdin Scientific

Amadis Chemical Company Limited Haoyuan Chemexpress Co., Ltd. MedChemexpress LLC Shanghai JiYi Biotechnology Co. Ltd.

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BenzaMide, N-[3-[3-[4-[(diMethylaMino)Methyl]phenyl]pyrazolo[1,5-a]pyriMidin-7-yl]phenyl]-3-(trifluoroMethyl)-

Properties

Safety Information

Description

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