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ChemicalBook >> CAS DataBase List >> 4-[1-Cyclohexyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]-2-pyrimidinaminedihydrochloride

4-[1-Cyclohexyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]-2-pyrimidinaminedihydrochloride

4-[1-Cyclohexyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]-2-pyrimidinaminedihydrochloride price.
  • $42 - $2395.3
  • Product name: 4-[1-Cyclohexyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]-2-pyrimidinaminedihydrochloride
  • CAS: 950912-80-8
  • MF: C19H20FN5.2HCl
  • MW: 410
  • EINECS:
  • MDL Number:MFCD12828759
  • Synonyms:PF670462/ PF-670462;4-[1-Cyclohexyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]-2-pyrimidinamine hydrochloride;2-PyriMidinaMine, 4-[1-cyclohexyl-4-(4-fluorophenyl)-1H-iMidazol-5-yl]-, hydrochloride (1:2);PF 67046;4-[1-Cyclohexyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]-2-pyrimidinamine hydrochloride PF670462;4-[3-Cyclohexyl-5-(4-fluoro-phenyl)-3H-imidazol-4-yl]-pyrimidin-2-ylamine dihydrochloride;PF 670462, >=98%;PF 670462
Price30 Properties Safety Information Description
30 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 50
  • 1mg
  • 5mg
  • 10
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • 10mM(in 1mL DMSO)
  • ManufacturerAK Scientific
  • Product number3966AH
  • Product description4-[3-Cyclohexyl-5-(4-fluorophenyl)imidazol-4-yl]pyrimidin-2-aminedihydrochloride
  • Packaging50mg
  • Price$451
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA124173
  • Product descriptionPF-670462 98+%
  • Packaging1mg
  • Price$42
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA124173
  • Product descriptionPF-670462 98+%
  • Packaging5mg
  • Price$71
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA124173
  • Product descriptionPF-670462 98+%
  • Packaging10mg
  • Price$92
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA124173
  • Product descriptionPF-670462 98+%
  • Packaging50mg
  • Price$284
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA124173
  • Product descriptionPF-670462 98+%
  • Packaging100mg
  • Price$384
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA124173
  • Product descriptionPF-670462 98+%
  • Packaging250mg
  • Price$782
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA124173
  • Product descriptionPF-670462 98+%
  • Packaging1g
  • Price$1960
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3719
  • Product descriptionPF-670462
  • Packaging10mM(in 1mL DMSO)
  • Price$145
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3719
  • Product descriptionPF-670462
  • Packaging50mg
  • Price$514
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146121
  • Product descriptionPF-670462 >99.5%
  • Packaging100mg
  • Price$765
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146121
  • Product descriptionPF-670462 >99.5%
  • Packaging250mg
  • Price$1208.7
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146121
  • Product descriptionPF-670462 >99.5%
  • Packaging1g
  • Price$2395.3
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFP65129
  • Product descriptionPF 670462
  • Packaging10mg
  • Price$85
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFP65129
  • Product descriptionPF 670462
  • Packaging50mg
  • Price$297.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number14588
  • Product descriptionPF-670462 (hydrochloride) ≥99%
  • Packaging10mg
  • Price$166
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3966AH 4-[3-Cyclohexyl-5-(4-fluorophenyl)imidazol-4-yl]pyrimidin-2-aminedihydrochloride 50mg $451 2021-12-16 Buy
Ambeed A124173 PF-670462 98+% 1mg $42 2021-12-16 Buy
Ambeed A124173 PF-670462 98+% 5mg $71 2021-12-16 Buy
Ambeed A124173 PF-670462 98+% 10mg $92 2021-12-16 Buy
Ambeed A124173 PF-670462 98+% 50mg $284 2021-12-16 Buy
Ambeed A124173 PF-670462 98+% 100mg $384 2021-12-16 Buy
Ambeed A124173 PF-670462 98+% 250mg $782 2021-12-16 Buy
Ambeed A124173 PF-670462 98+% 1g $1960 2021-12-16 Buy
ApexBio Technology A3719 PF-670462 10mM(in 1mL DMSO) $145 2021-12-16 Buy
ApexBio Technology A3719 PF-670462 50mg $514 2021-12-16 Buy
Biorbyt Ltd orb146121 PF-670462 >99.5% 100mg $765 2021-12-16 Buy
Biorbyt Ltd orb146121 PF-670462 >99.5% 250mg $1208.7 2021-12-16 Buy
Biorbyt Ltd orb146121 PF-670462 >99.5% 1g $2395.3 2021-12-16 Buy
Biosynth Carbosynth FP65129 PF 670462 10mg $85 2021-12-16 Buy
Biosynth Carbosynth FP65129 PF 670462 50mg $297.5 2021-12-16 Buy
Cayman Chemical 14588 PF-670462 (hydrochloride) ≥99% 10mg $166 2024-03-01 Buy
Next Last

Properties

Melting point :>178°C (dec.)
storage temp. :2-8°C
solubility :H2O: soluble2mg/mL, clear (warmed)
form :powder
color :white to beige
InChIKey :PSNKGVAXBSAHCH-UHFFFAOYSA-N

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

The casein kinase 1 (CK1) family of kinases regulate diverse processes, particularly related to circadian rhythms and sensitivity to amphetamines. PF-670462 is a potent inhibitor of the CK1 isoforms CK1ε and CK1δ (IC50 = 7.7 and 14 nM, respectively). It less effectively inhibits a wide variety of related or common kinases. Through its effects on CK1, PF-670462 disrupts circadian rhythms in cells and animals. It also blocks the locomotor response to amphetamines in mice.

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Suppliers and manufacturers

career henan chemical co
4-[1-Cyclohexyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]-2-pyrimidinaminedihydrochloride
$1.00 /1KG
4-[1-Cyclohexyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]-2-pyrimidinaminedihydrochloride CAS:950912-80-8
Hangzhou FandaChem Co.,Ltd.
BOC Sciences
Alfa Chemistry
InvivoChem
TargetMol Chemicals Inc.
ShenZhen Trendseen Biological Technology Co.,Ltd.
Wuhan Topule Biopharmaceutical Co., Ltd
LEAPCHEM CO., LTD.
Aladdin Scientific