1,2-EthanediaMine, N,N'-bis(diphenylMethyl)-, dihydrochloride
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- $72 - $763
- Product name: 1,2-EthanediaMine, N,N'-bis(diphenylMethyl)-, dihydrochloride
- CAS: 97075-46-2
- MF: C28H29ClN2
- MW: 429
- EINECS:
- MDL Number:MFCD08702723
- Synonyms:1,2-EthanediaMine, N,N'-bis(diphenylMethyl)-, dihydrochloride;N,N'-dibenzhydrylethane-1,2-diamine;N1,N2-Dibenzhydrylethane-1,2-diamine dihydrochloride;1,2-EthanediaMine, N,N'-bis(diphenylMethyl)-, dihydrochloride
9 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Cayman Chemical
- ChemScene
- Sigma-Aldrich
- TRC
Package
- 5mg
- 10mg
- 25mg
- 50mg
- ManufacturerAK Scientific
- Product number9955CS
- Product descriptionAMN082dihydrochloride
- Packaging25mg
- Price$397
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7034
- Product descriptionAMN082dihydrochloride
- Packaging10mg
- Price$182
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7034
- Product descriptionAMN082dihydrochloride
- Packaging50mg
- Price$763
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number28779
- Product descriptionAMN082
- Packaging5mg
- Price$72
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number28779
- Product descriptionAMN082
- Packaging10mg
- Price$128
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number28779
- Product descriptionAMN082
- Packaging25mg
- Price$284
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0028099
- Product descriptionAMN082
- Packaging5mg
- Price$170
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product number5.04745
- Product descriptionAMN082 Dihydrochloride - CAS 97075-46-2 - Calbiochem
- Packaging10MG
- Price$115
- Updated2022-05-15
- Buy
- ManufacturerTRC
- Product numberA634613
- Product descriptionAMN082Dihydrochloride
- Packaging5mg
- Price$350
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 9955CS | AMN082dihydrochloride | 25mg | $397 | 2021-12-16 | Buy |
| ApexBio Technology | B7034 | AMN082dihydrochloride | 10mg | $182 | 2021-12-16 | Buy |
| ApexBio Technology | B7034 | AMN082dihydrochloride | 50mg | $763 | 2021-12-16 | Buy |
| Cayman Chemical | 28779 | AMN082 | 5mg | $72 | 2024-03-01 | Buy |
| Cayman Chemical | 28779 | AMN082 | 10mg | $128 | 2024-03-01 | Buy |
| Cayman Chemical | 28779 | AMN082 | 25mg | $284 | 2024-03-01 | Buy |
| ChemScene | CS-0028099 | AMN082 | 5mg | $170 | 2021-12-16 | Buy |
| Sigma-Aldrich | 5.04745 | AMN082 Dihydrochloride - CAS 97075-46-2 - Calbiochem | 10MG | $115 | 2022-05-15 | Buy |
| TRC | A634613 | AMN082Dihydrochloride | 5mg | $350 | 2021-12-16 | Buy |
Properties
storage temp. :-20°C
solubility :<46.55mg/ml in DMSO;insoluble in H2O
form :solid
color :White
solubility :<46.55mg/ml in DMSO;insoluble in H2O
form :solid
color :White
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
AMN082 is an orally bioavailable allosteric agonist of metabotropic glutamate receptor 7 (mGluR7). It inhibits cAMP accumulation induced by forskolin in CHO cells expressing human mGluR7b (EC50 = 64 nM). AMN082 (10 μM) is selective for mGluR7a and mGluR7b over mGluR1b, mGluR4, and mGluR8a with 140, 90, 15, 18, and 20% activation, respectively, as well as over mGluR2, mGluR3, mGluR5a, mGluR6, GluR3, and NMDA receptors containing NR1a, NR2A, or NR2B subunits. AMN082 also binds to the norepinephrine transporter (NET) and α1-adrenergic receptor (α1-AR). It increases the proliferation of neural progenitor cells (NPCs) and induces their differentiation into neurons when used at a concentration of 1 μM. AMN082 (2.5 mg/kg) inhibits apomorphine-induced circling in a rat model of Parkinson''s disease induced by 6-hydroxy dopamine (6-OHDA; ).Suppliers and manufacturers
TargetMol Chemicals Inc.
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Shenzhen Regent Biochemical Technology Co., Ltd.
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.
MedBioPharmaceutical Technology Inc
Jinan Jiuli Biotechnology Co. , Ltd.
Beijing Jin Ming Biotechnology Co., Ltd.