A 54556A
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- $340 - $1353
- Product name: A 54556A
- CAS: 95398-45-1
- MF: C38H50N6O8
- MW: 718.839
- EINECS:
- MDL Number:
- Synonyms:A 54556A;PubChem ID: 24767779;A 54556A (~90%);Antibiotic A-54556A;L-Proline, N-[(2E,4E,6E)-1-oxo-2,4,6-octatrien-1-yl]-L-phenylalanyl-L-seryl-L-prolyl-N-methyl-L-alanyl-L-alanyl-4-methyl-, (6→2)-lactone, (4R)-
7 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Cayman Chemical
- TRC
Package
- 1mg
- 2.5mg
- 5mg
- ManufacturerAK Scientific
- Product number1350DC
- Product description(2E,4E,6E)-N-[(2S)-1-Oxo-3-phenyl-1-[[(3S,7S,9R,13S,16S,19S)-9,13,16,17-tetramethyl-2,6,12,15,18-pentaoxo-5-oxa-1,11,14,17-tetrazatricyclo[17.3.0.07,11]docosan-3-yl]amino]propan-2-yl]octa-2,4,6-trienamide
- Packaging1mg
- Price$476
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3173
- Product descriptionA-54556A
- Packaging1mg
- Price$387
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3173
- Product descriptionA-54556A
- Packaging5mg
- Price$1353
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number15305
- Product descriptionA-54556A ≥95%
- Packaging1mg
- Price$340
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15305
- Product descriptionA-54556A ≥95%
- Packaging5mg
- Price$1186
- Updated2024-03-01
- Buy
- ManufacturerTRC
- Product numberA101055
- Product descriptionA54556A(~90%)
- Packaging1mg
- Price$545
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberA101055
- Product descriptionA54556A(~90%)
- Packaging2.5mg
- Price$1185
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 1350DC | (2E,4E,6E)-N-[(2S)-1-Oxo-3-phenyl-1-[[(3S,7S,9R,13S,16S,19S)-9,13,16,17-tetramethyl-2,6,12,15,18-pentaoxo-5-oxa-1,11,14,17-tetrazatricyclo[17.3.0.07,11]docosan-3-yl]amino]propan-2-yl]octa-2,4,6-trienamide | 1mg | $476 | 2021-12-16 | Buy |
| ApexBio Technology | C3173 | A-54556A | 1mg | $387 | 2021-12-16 | Buy |
| ApexBio Technology | C3173 | A-54556A | 5mg | $1353 | 2021-12-16 | Buy |
| Cayman Chemical | 15305 | A-54556A ≥95% | 1mg | $340 | 2024-03-01 | Buy |
| Cayman Chemical | 15305 | A-54556A ≥95% | 5mg | $1186 | 2024-03-01 | Buy |
| TRC | A101055 | A54556A(~90%) | 1mg | $545 | 2021-12-16 | Buy |
| TRC | A101055 | A54556A(~90%) | 2.5mg | $1185 | 2021-12-16 | Buy |
Properties
Melting point :>180oC (dec.)
Boiling point :1086.9±65.0 °C(Predicted)
Density :1.28±0.1 g/cm3(Predicted)
storage temp. :Amber Vial, Refrigerator
solubility :Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :12.80±0.46(Predicted)
color :Pale Yellow to Light Brown
Stability :Light Sensitive
Boiling point :1086.9±65.0 °C(Predicted)
Density :1.28±0.1 g/cm3(Predicted)
storage temp. :Amber Vial, Refrigerator
solubility :Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :12.80±0.46(Predicted)
color :Pale Yellow to Light Brown
Stability :Light Sensitive
Safety Information
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Description
A-54556A is a natural acyldepsipeptide (ADEP) antibiotic isolated from the fermentation broth of S. hawaiiensis. Like other ADEP antibiotics, A-54556A binds to the ATP-dependent Clp protease proteolytic subunit ClpP, resulting in constitutive activation of this bacterial protease. This leads to uncontrolled proteolysis, inhibition of bacterial cell division, and, ultimately, cell death. A-54556A preferentially targets Gram-positive bacteria, including staphylococci, streptococci, and enterococci, with minimum inhibitory concentration values in the submicrogram/milliliter range. ADEP antibiotics are effective against chronic infections as they are able to eradicate chronic biofilm infections, particularly when combined with rifampicin.Suppliers and manufacturers
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