A-966492
- $32 - $9556.47
- Product name: A-966492
- CAS: 934162-61-5
- MF: C18H17FN4O
- MW: 324.35
- EINECS:
- MDL Number:MFCD17215207
- Synonyms:A-966492;2-[2-Fluoro-4-[(2S)-2-pyrrolidinyl]phenyl]-1H-benzimidazole-7-carboxamide;A-966492(A 966492);2-{2-fluoro-4-[(2S)-pyrrolidin-2-yl]phenyl}-1H-1,3-benzodiazole-7-carboxaMide;2-[2-Fluoro-4-[(2S)-2-pyrrolidinyl]phenyl]-1H-benzimidazole-7-carboxamide A-966492;A-966492, >=98%;A966492;A 966492;A-966492;CS-903
27 prices
Selected condition:
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
Package
- 1mg
- 5MG
- 10MG
- 25mg
- 50MG
- 100mg
- 200mg
- 250mg
- 1G
- 1000mg
- ManufacturerAK Scientific
- Product number2192AH
- Product descriptionA-966492
- Packaging25mg
- Price$1548
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000929
- Product descriptionA-966492 95.00%
- Packaging5MG
- Price$620
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000929
- Product descriptionA-966492 95.00%
- Packaging10MG
- Price$1006.58
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000929
- Product descriptionA-966492 95.00%
- Packaging50MG
- Price$1855.51
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000929
- Product descriptionA-966492 95.00%
- Packaging1G
- Price$9556.47
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4160
- Product descriptionA-966492
- Packaging5mg
- Price$110
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4160
- Product descriptionA-966492
- Packaging10mg
- Price$190
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4160
- Product descriptionA-966492
- Packaging50mg
- Price$590
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4160
- Product descriptionA-966492
- Packaging200mg
- Price$1490
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180912
- Product descriptionA-966492 >98%
- Packaging100mg
- Price$1802
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180912
- Product descriptionA-966492 >98%
- Packaging250mg
- Price$2839
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180912
- Product descriptionA-966492 >98%
- Packaging1000mg
- Price$5210.5
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA100934
- Product descriptionA 966492
- Packaging10mg
- Price$175
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA100934
- Product descriptionA 966492
- Packaging50mg
- Price$612.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number26378
- Product descriptionA-966492
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number26378
- Product descriptionA-966492
- Packaging5mg
- Price$139
- Updated2024-03-01
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 2192AH | A-966492 | 25mg | $1548 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | KIN0000929 | A-966492 95.00% | 5MG | $620 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | KIN0000929 | A-966492 95.00% | 10MG | $1006.58 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | KIN0000929 | A-966492 95.00% | 50MG | $1855.51 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | KIN0000929 | A-966492 95.00% | 1G | $9556.47 | 2021-12-16 | Buy |
ApexBio Technology | A4160 | A-966492 | 5mg | $110 | 2021-12-16 | Buy |
ApexBio Technology | A4160 | A-966492 | 10mg | $190 | 2021-12-16 | Buy |
ApexBio Technology | A4160 | A-966492 | 50mg | $590 | 2021-12-16 | Buy |
ApexBio Technology | A4160 | A-966492 | 200mg | $1490 | 2021-12-16 | Buy |
Biorbyt Ltd | orb180912 | A-966492 >98% | 100mg | $1802 | 2021-12-16 | Buy |
Biorbyt Ltd | orb180912 | A-966492 >98% | 250mg | $2839 | 2021-12-16 | Buy |
Biorbyt Ltd | orb180912 | A-966492 >98% | 1000mg | $5210.5 | 2021-12-16 | Buy |
Biosynth Carbosynth | FA100934 | A 966492 | 10mg | $175 | 2021-12-16 | Buy |
Biosynth Carbosynth | FA100934 | A 966492 | 50mg | $612.5 | 2021-12-16 | Buy |
Cayman Chemical | 26378 | A-966492 | 1mg | $32 | 2024-03-01 | Buy |
Cayman Chemical | 26378 | A-966492 | 5mg | $139 | 2024-03-01 | Buy |
Properties
Boiling point :605.5±65.0 °C(Predicted)
Density :1.335
storage temp. :Store at -20°C
solubility :≥32.4 mg/mL in DMSO; ≥16.53 mg/mL in H2O with ultrasonic; ≥3.16 mg/mL in EtOH with gentle warming and ultrasonic
form :solid
pka :9.33±0.30(Predicted)
color :White to off-white
Density :1.335
storage temp. :Store at -20°C
solubility :≥32.4 mg/mL in DMSO; ≥16.53 mg/mL in H2O with ultrasonic; ≥3.16 mg/mL in EtOH with gentle warming and ultrasonic
form :solid
pka :9.33±0.30(Predicted)
color :White to off-white
Safety Information
Symbol(GHS): | ||||||||
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Signal word: | Warning | |||||||
Hazard statements: |
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Precautionary statements: |
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Description
A-966492 effectively inhibits PARP-1 with an EC50 of 1 nM and a Ki value of 1 nM. When it acts on PARP-2, the Ki value is 1.5 nM. It has excellent efficacy on PARP enzyme, especially on C41 cells. A-966492 significantly enhanced the effect of TMZ in a dose-dependent manner.Related product price
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$5-2400 - 2-[(2R)-2-Methylpyrrolidin-2-yl]-1H-benimidazole-4-
carboxamide
$28-4644
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