A66
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- $36 - $4171.86
- Product name: A66
- CAS: 1166227-08-2
- MF: C17H23N5O2S2
- MW: 393.53
- EINECS:-0
- MDL Number:MFCD22378485
- Synonyms:(2S)-N1-[2-(tert-Butyl)-4'-methyl[4,5'-bithiazol]-2'-yl]-1,2-pyrrolidinedicarboxamide;(2S)-N1-(5-(2-tert-butylthiazol-4-yl)-4-methylthiazol-2-yl)pyrrolidine-1,2-dicarboxamide;(2S)-N1-[2-(tert-Butyl)-4'-methyl[4,5'-bithiazol]-2'-yl]-1,2-pyrrolidinedicarboxamide A 66;CS-435;A66, 98%, a potent and specific p110α inhibitor;(2S)-N1-[2-(1,1-Dimethylethyl)-4'-methyl[4,5'-bithiazol]-2'-yl]-1,2-pyrrolidinedicarboxamide;A 66;A-66;1,2-Pyrrolidinedicarboxamide, N1-[2-(1,1-dimethylethyl)-4'-methyl[4,5'-bithiazol]-2'-yl]-, (2S)-
36 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Axon Medchem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- TRC
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 200MG
- 250mg
- 1g
- 10mM(in 1mL DMSO)
- ManufacturerAK Scientific
- Product numberX7447
- Product description(2S)-N1-(5-(2-tert-butylthiazol-4-yl)-4-methylthiazol-2-yl)pyrrolidine-1,2-dicarboxamide
- Packaging10mg
- Price$218
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberX7447
- Product description(2S)-N1-(5-(2-tert-butylthiazol-4-yl)-4-methylthiazol-2-yl)pyrrolidine-1,2-dicarboxamide
- Packaging50mg
- Price$640
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA102947
- Product descriptionA66 98+%
- Packaging1mg
- Price$44
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA102947
- Product descriptionA66 98+%
- Packaging5mg
- Price$135
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA102947
- Product descriptionA66 98+%
- Packaging10mg
- Price$203
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA102947
- Product descriptionA66 98+%
- Packaging50mg
- Price$622
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0002406
- Product descriptionA66 95.00%
- Packaging5MG
- Price$257.4
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0002406
- Product descriptionA66 95.00%
- Packaging50MG
- Price$2088.36
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0002406
- Product descriptionA66 95.00%
- Packaging200MG
- Price$4171.86
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8354
- Product descriptionA66
- Packaging5mg
- Price$104
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8354
- Product descriptionA66
- Packaging10mM(in 1mL DMSO)
- Price$108
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8354
- Product descriptionA66
- Packaging10mg
- Price$184
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8354
- Product descriptionA66
- Packaging50mg
- Price$627
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60089
- Product descriptionA66 ≥98%
- Packaging10mg
- Price$338
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon1831
- Product descriptionA66 99%
- Packaging25mg
- Price$390.5
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb611611
- Product descriptionCCT128930
- Packaging100mg
- Price$690.2
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | X7447 | (2S)-N1-(5-(2-tert-butylthiazol-4-yl)-4-methylthiazol-2-yl)pyrrolidine-1,2-dicarboxamide | 10mg | $218 | 2021-12-16 | Buy |
| AK Scientific | X7447 | (2S)-N1-(5-(2-tert-butylthiazol-4-yl)-4-methylthiazol-2-yl)pyrrolidine-1,2-dicarboxamide | 50mg | $640 | 2021-12-16 | Buy |
| Ambeed | A102947 | A66 98+% | 1mg | $44 | 2021-12-16 | Buy |
| Ambeed | A102947 | A66 98+% | 5mg | $135 | 2021-12-16 | Buy |
| Ambeed | A102947 | A66 98+% | 10mg | $203 | 2021-12-16 | Buy |
| Ambeed | A102947 | A66 98+% | 50mg | $622 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0002406 | A66 95.00% | 5MG | $257.4 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0002406 | A66 95.00% | 50MG | $2088.36 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0002406 | A66 95.00% | 200MG | $4171.86 | 2021-12-16 | Buy |
| ApexBio Technology | A8354 | A66 | 5mg | $104 | 2021-12-16 | Buy |
| ApexBio Technology | A8354 | A66 | 10mM(in 1mL DMSO) | $108 | 2021-12-16 | Buy |
| ApexBio Technology | A8354 | A66 | 10mg | $184 | 2021-12-16 | Buy |
| ApexBio Technology | A8354 | A66 | 50mg | $627 | 2021-12-16 | Buy |
| Arctom | CFN60089 | A66 ≥98% | 10mg | $338 | 2021-12-16 | Buy |
| Axon Medchem | Axon1831 | A66 99% | 25mg | $390.5 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb611611 | CCT128930 | 100mg | $690.2 | 2021-12-16 | Buy |
Properties
Density :1.354
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :insoluble in H2O; ≥19.7 mg/mL in DMSO; ≥2.63 mg/mL in EtOH with gentle warming
form :solid
pka :6.27±0.70(Predicted)
color :Off-white to light yellow
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :insoluble in H2O; ≥19.7 mg/mL in DMSO; ≥2.63 mg/mL in EtOH with gentle warming
form :solid
pka :6.27±0.70(Predicted)
color :Off-white to light yellow
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
A-66 is a potent, selective inhibitor of the PI3K isoform p110α (IC50 = 32 nM in a cell-free assay). It displays over 100-fold selectivity for p110α over other isoforms. A-66 is effective in vivo, suppressing the growth of SK-OV-3 tumor xenografts in mice. It also impairs all measures of in vivo insulin action in mice. A-66 partially suppresses B cell receptor-dependent Akt activation and proliferation.More related product prices
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