CAL-101
- $33 - $3603.6
- Product name: CAL-101
- CAS: 870281-82-6
- MF: C22H18FN7O
- MW: 415.42
- EINECS:807-438-9
- MDL Number:MFCD19443647
- Synonyms:CAL101,CAL-101;CAL-101;GS1101;CAL-101 (GS-1101);5-Fluoro-3-phenyl-2-[(1S)-1-(9H-purin-6-ylamino)propyl]-4(3H)-quinazolinone;CAL-101 (Idelalisib, GS-1101);(S)-2-(1-((9H-Purin-6-yl)aMino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one;4(3H)-Quinazolinone, 5-fluoro-3-phenyl-2-[(1S)-1-(1H-purin-6-ylaMino)propyl]-
30 prices
Selected condition:
Brand
- Abosyn
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Axon Medchem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- ChemScene
- DC Chemicals
- Labseeker
- Matrix Scientific
- TRC
Package
- 1MG
- 5mg
- 10mg
- 20mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- 5g
- 10g
- 50G
- ManufacturerAbosyn
- Product number61-10788
- Product description(S)-2-(1-((9H-Purin-6-yl)amino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one 95-98%
- Packaging1g
- Price$225
- Updated2021-12-16
- Buy
- ManufacturerAbosyn
- Product number61-10788
- Product description(S)-2-(1-((9H-Purin-6-yl)amino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one 95-98%
- Packaging5g
- Price$675
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberSYN5707
- Product descriptionCAL-101
- Packaging10mg
- Price$123
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberSYN5707
- Product descriptionCAL-101
- Packaging50mg
- Price$406
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0024413
- Product descriptionCAL-101 95.00%
- Packaging1MG
- Price$667.01
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0024413
- Product descriptionCAL-101 95.00%
- Packaging50G
- Price$3603.6
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3005
- Product descriptionCAL-101(Idelalisib,GS-1101)
- Packaging100mg
- Price$220
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60050
- Product descriptionIdelalisib(CAL-101) ≥98%
- Packaging20mg
- Price$218
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2170
- Product descriptionCAL101-Idelalisib 99%
- Packaging5mg
- Price$104.5
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146250
- Product descriptionIdelalisib (CAL-101,GS-1101) >99.5%,ee > 99%
- Packaging100mg
- Price$510
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146250
- Product descriptionIdelalisib (CAL-101,GS-1101) >99.5%,ee > 99%
- Packaging250mg
- Price$690.2
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146250
- Product descriptionIdelalisib (CAL-101,GS-1101) >99.5%,ee > 99%
- Packaging1g
- Price$1356.6
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFI29231
- Product descriptionIdelalisib
- Packaging10mg
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFI29231
- Product descriptionIdelalisib
- Packaging50mg
- Price$263
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number15279
- Product descriptionCAL-101 ≥98%
- Packaging5mg
- Price$33
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15279
- Product descriptionCAL-101 ≥98%
- Packaging10mg
- Price$63
- Updated2024-03-01
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Abosyn | 61-10788 | (S)-2-(1-((9H-Purin-6-yl)amino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one 95-98% | 1g | $225 | 2021-12-16 | Buy |
Abosyn | 61-10788 | (S)-2-(1-((9H-Purin-6-yl)amino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one 95-98% | 5g | $675 | 2021-12-16 | Buy |
AK Scientific | SYN5707 | CAL-101 | 10mg | $123 | 2021-12-16 | Buy |
AK Scientific | SYN5707 | CAL-101 | 50mg | $406 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0024413 | CAL-101 95.00% | 1MG | $667.01 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0024413 | CAL-101 95.00% | 50G | $3603.6 | 2021-12-16 | Buy |
ApexBio Technology | A3005 | CAL-101(Idelalisib,GS-1101) | 100mg | $220 | 2021-12-16 | Buy |
Arctom | CFN60050 | Idelalisib(CAL-101) ≥98% | 20mg | $218 | 2021-12-16 | Buy |
Axon Medchem | Axon2170 | CAL101-Idelalisib 99% | 5mg | $104.5 | 2021-12-16 | Buy |
Biorbyt Ltd | orb146250 | Idelalisib (CAL-101,GS-1101) >99.5%,ee > 99% | 100mg | $510 | 2021-12-16 | Buy |
Biorbyt Ltd | orb146250 | Idelalisib (CAL-101,GS-1101) >99.5%,ee > 99% | 250mg | $690.2 | 2021-12-16 | Buy |
Biorbyt Ltd | orb146250 | Idelalisib (CAL-101,GS-1101) >99.5%,ee > 99% | 1g | $1356.6 | 2021-12-16 | Buy |
Biosynth Carbosynth | FI29231 | Idelalisib | 10mg | $75 | 2021-12-16 | Buy |
Biosynth Carbosynth | FI29231 | Idelalisib | 50mg | $263 | 2021-12-16 | Buy |
Cayman Chemical | 15279 | CAL-101 ≥98% | 5mg | $33 | 2024-03-01 | Buy |
Cayman Chemical | 15279 | CAL-101 ≥98% | 10mg | $63 | 2024-03-01 | Buy |
Properties
Melting point :250-252oC
Boiling point :733.4±70.0 °C(Predicted)
Density :1.47
storage temp. :-20°C
solubility :Soluble in DMSO (>25 mg/ml)
form :White solid.
pka :10.00±0.10(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Boiling point :733.4±70.0 °C(Predicted)
Density :1.47
storage temp. :-20°C
solubility :Soluble in DMSO (>25 mg/ml)
form :White solid.
pka :10.00±0.10(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Safety Information
Symbol(GHS): | |||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Signal word: | Danger | ||||||||||||||
Hazard statements: |
|
||||||||||||||
Precautionary statements: |
|
Description
The phosphatidylinositol 3-kinase (PI3K) signaling pathway has central roles in cell growth, development, and survival. CAL-101 is a cell permeable inhibitor of the PI3K catalytic subunit p110δ (IC50 = 2.5 nM) that demonstrates 40- to 300-fold selectivity against other PI3K class I enzymes (IC50s = 820, 565, and 89 nM for p110α, β, and γ, respectively). At 1 μM it can block constitutive PI3K signaling in malignant B-cell lines and primary patient tumor cells, resulting in decreased phosphorylation of Akt and other downstream effectors, an increase in poly(ADP-ribose) polymerase, and apoptosis. It has also been shown to inhibit the chemotaxis of chronic lymphocytic leukemia cells and to downregulate the secretion of chemokines triggered by B-cell receptor signaling.More related product prices
Ibrutinib IPI 145 Pictilisib (GDC-0941) BKM120 (NVP-BKM120, Buparlisib) Bortezomib Everolimus 2-Fluoro-6-nitro-N-phenylbenzamide (S)-tert-butyl (1-(5-fluoro-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)propyl)carbaMate BOC-ABU-OH (S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one 2-Amino-6-fluorobenzoic acid 405169-16-6 ARRY-334543 Momelotinib CO-1686Related product price
- Ibrutinib
$5-1208.7 - IPI 145
$68-2550 - Pictilisib (GDC-0941)
$49-3563.2
Suppliers and manufacturers
Capot Chemical Co.,Ltd.
ATK CHEMICAL COMPANY LIMITED
Lianyungang happen teng technology co., LTD
Zhejiang ZETian Fine Chemicals Co. LTD
Biochempartner
Hangzhou Cyanochem Co., Ltd.
Hubei xin bonus chemical co. LTD