ABT-199
- $12 - $4766.8
- Product name: ABT-199
- CAS: 1257044-40-8
- MF: C45H50ClN7O7S
- MW: 868.44
- EINECS:820-130-9
- MDL Number:MFCD23160052
- Synonyms:ABT-199;ABT-199 (GDC-0199);GDC-0199;ABT-199 100MG;2-(1H-Pyrrolo[2,3-b]pyridin-5-yloxy)-4-(4-((2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-enyl)met;ABT-199, Venetoclax;GDC 0199;GDC0199;Benzamide, 4-[4-[[2-(4-chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[3-nitro-4-[[(tetrahydro-2H-pyran-4-yl)methyl]amino]phenyl]sulfonyl]-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-
38 prices
Selected condition:
Brand
- AK Scientific
- Ambeed
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Crysdot
- DC Chemicals
- Matrix Scientific
- Tocris
- TRC
Package
- 20mg
- 25mg
- 50mg
- 50 mg
- 50
- 10g
- 500mg
- 100 mg
- 10
- 10mM(in 1mL DMSO)
- 1mg
- 1unit
- 2mg
- 5mg
- 10mg
- 100mg
- 250mg
- 1g
- 5g
- ManufacturerAK Scientific
- Product numberX3609
- Product descriptionVenetoclax
- Packaging100mg
- Price$1667
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberSYN5490
- Product descriptionABT-199
- Packaging10mg
- Price$113
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA156386
- Product description2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide 99+%
- Packaging5g
- Price$302
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA156386
- Product description2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide 99+%
- Packaging1g
- Price$96
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA156386
- Product description2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide 99+%
- Packaging250mg
- Price$48
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA156386
- Product description2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide 99+%
- Packaging10mg
- Price$23
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA156386
- Product description2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide 99+%
- Packaging5mg
- Price$19
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA156386
- Product description2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide 99+%
- Packaging2mg
- Price$15
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA156386
- Product description2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide 99+%
- Packaging1mg
- Price$12
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8194
- Product descriptionABT-199
- Packaging1unit
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8194
- Product descriptionABT-199
- Packaging1mg
- Price$42
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8194
- Product descriptionABT-199
- Packaging5mg
- Price$126
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8194
- Product descriptionABT-199
- Packaging10mM(in 1mL DMSO)
- Price$153
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8194
- Product descriptionABT-199
- Packaging50mg
- Price$456
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60007
- Product descriptionVenetoclax(ABT-199) ≥98%
- Packaging20mg
- Price$188
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146094
- Product descriptionVenetoclax (ABT-199) >99%
- Packaging1g
- Price$1208.7
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | X3609 | Venetoclax | 100mg | $1667 | 2021-12-16 | Buy |
AK Scientific | SYN5490 | ABT-199 | 10mg | $113 | 2021-12-16 | Buy |
Ambeed | A156386 | 2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide 99+% | 5g | $302 | 2021-12-16 | Buy |
Ambeed | A156386 | 2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide 99+% | 1g | $96 | 2021-12-16 | Buy |
Ambeed | A156386 | 2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide 99+% | 250mg | $48 | 2021-12-16 | Buy |
Ambeed | A156386 | 2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide 99+% | 10mg | $23 | 2021-12-16 | Buy |
Ambeed | A156386 | 2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide 99+% | 5mg | $19 | 2021-12-16 | Buy |
Ambeed | A156386 | 2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide 99+% | 2mg | $15 | 2021-12-16 | Buy |
Ambeed | A156386 | 2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide 99+% | 1mg | $12 | 2021-12-16 | Buy |
ApexBio Technology | A8194 | ABT-199 | 1unit | $28 | 2021-12-16 | Buy |
ApexBio Technology | A8194 | ABT-199 | 1mg | $42 | 2021-12-16 | Buy |
ApexBio Technology | A8194 | ABT-199 | 5mg | $126 | 2021-12-16 | Buy |
ApexBio Technology | A8194 | ABT-199 | 10mM(in 1mL DMSO) | $153 | 2021-12-16 | Buy |
ApexBio Technology | A8194 | ABT-199 | 50mg | $456 | 2021-12-16 | Buy |
Arctom | CFN60007 | Venetoclax(ABT-199) ≥98% | 20mg | $188 | 2021-12-16 | Buy |
Biorbyt Ltd | orb146094 | Venetoclax (ABT-199) >99% | 1g | $1208.7 | 2021-12-16 | Buy |
Properties
Melting point :>150°C (dec.)
Density :1.340±0.06 g/cm3(Predicted)
storage temp. :-20°C Freezer
solubility :DMSO (Slightly)
form :Yellow solid.
pka :4.09±0.10(Predicted)
color :Light Yellow to Yellow
InChIKey :LQBVNQSMGBZMKD-UHFFFAOYSA-N
SMILES :C(NS(C1=CC=C(NCC2CCOCC2)C([N+]([O-])=O)=C1)(=O)=O)(=O)C1=CC=C(N2CCN(CC3CCC(C)(C)CC=3C3=CC=C(Cl)C=C3)CC2)C=C1OC1=CN=C2NC=CC2=C1
Density :1.340±0.06 g/cm3(Predicted)
storage temp. :-20°C Freezer
solubility :DMSO (Slightly)
form :Yellow solid.
pka :4.09±0.10(Predicted)
color :Light Yellow to Yellow
InChIKey :LQBVNQSMGBZMKD-UHFFFAOYSA-N
SMILES :C(NS(C1=CC=C(NCC2CCOCC2)C([N+]([O-])=O)=C1)(=O)=O)(=O)C1=CC=C(N2CCN(CC3CCC(C)(C)CC=3C3=CC=C(Cl)C=C3)CC2)C=C1OC1=CN=C2NC=CC2=C1
Safety Information
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Signal word: | Danger | ||||||||||||||||||||||
Hazard statements: |
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Precautionary statements: |
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Description
ABT-199, also known as venetoclax, is a small, oral chemical molecule used for the treatment of chronic lymphocytic leukemia (CLL) associated with a specific chromosomal abnormality. As a second line treatment drug of CLL, ABT-199 take effects through acting as a BH3-mimetic and inhibitor of Bcl-2 (the anti-apoptotic B-cell lymphoma-2protein), further inducing apoptosis of CLL cells but not platelets. It also has the potential for the treatment of ER-positive breast cancer.More related product prices
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Suppliers and manufacturers
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