ABT-888
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- $44 - $1980
- Product name: ABT-888
- CAS: 912445-05-7
- MF: C13H16N4O
- MW: 244.296
- EINECS:1592732-453-0
- MDL Number:MFCD12407402
- Synonyms:ABT-888;2-[(2R)-2-Methylpyrrolidin-2-yl]-1H-benimidazole-4- carboxamide,dihydrochloridesalt;2-[(2R)-2-Methyl-2-pyrrolidinyl]-1H-benzimidazole-4-carboxamide dihydrochloride;Veliparib dihydrochloride;ABT-888(Veliparib dihydrochloride);ABT-888 dihydrochloride;ABT888 HCl;Veliparib hydrochloride
27 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Axon Medchem
- Cayman Chemical
- ChemScene
- DC Chemicals
- Matrix Scientific
- Tocris
Package
- 1mg
- 5MG
- 10mg
- 50
- 2x10mg
- 25MG
- 50mg
- 10mM(in 1mL DMSO)
- 100mg
- 200mg
- 250mg
- 500mg
- 1g
- ManufacturerAK Scientific
- Product numberSYN5722
- Product descriptionABT-888
- Packaging50mg
- Price$547
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000299
- Product description2-[(2R)-2-METHYLPYRROLIDIN-2-YL]-1H-BENIMIDAZOLE-4-CARBOXAMIDE DIHYDROCHLORIDE 95.00%
- Packaging5MG
- Price$724.19
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000299
- Product description2-[(2R)-2-METHYLPYRROLIDIN-2-YL]-1H-BENIMIDAZOLE-4-CARBOXAMIDE DIHYDROCHLORIDE 95.00%
- Packaging25MG
- Price$1000.52
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3958
- Product descriptionVeliparibdihydrochloride
- Packaging10mM(in 1mL DMSO)
- Price$57
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3958
- Product descriptionVeliparibdihydrochloride
- Packaging5mg
- Price$65
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3958
- Product descriptionVeliparibdihydrochloride
- Packaging10mg
- Price$85
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3958
- Product descriptionVeliparibdihydrochloride
- Packaging50mg
- Price$260
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3958
- Product descriptionVeliparibdihydrochloride
- Packaging200mg
- Price$678
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2888
- Product descriptionABT888dihydrochloride-Veliparibdihydrochloride|A861695dihydrochloride 99%
- Packaging2x10mg
- Price$154
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2888
- Product descriptionABT888dihydrochloride-Veliparibdihydrochloride|A861695dihydrochloride 99%
- Packaging50mg
- Price$313.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number11505
- Product descriptionABT-888 (hydrochloride) ≥98%
- Packaging1mg
- Price$44
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number11505
- Product descriptionABT-888 (hydrochloride) ≥98%
- Packaging5mg
- Price$109
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number11505
- Product descriptionABT-888 (hydrochloride) ≥98%
- Packaging10mg
- Price$142
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number11505
- Product descriptionABT-888 (hydrochloride) ≥98%
- Packaging25mg
- Price$267
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0077
- Product descriptionVeliparibdihydrochloride 99.96%
- Packaging5mg
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0077
- Product descriptionVeliparibdihydrochloride 99.96%
- Packaging10mg
- Price$84
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | SYN5722 | ABT-888 | 50mg | $547 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000299 | 2-[(2R)-2-METHYLPYRROLIDIN-2-YL]-1H-BENIMIDAZOLE-4-CARBOXAMIDE DIHYDROCHLORIDE 95.00% | 5MG | $724.19 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000299 | 2-[(2R)-2-METHYLPYRROLIDIN-2-YL]-1H-BENIMIDAZOLE-4-CARBOXAMIDE DIHYDROCHLORIDE 95.00% | 25MG | $1000.52 | 2021-12-16 | Buy |
| ApexBio Technology | A3958 | Veliparibdihydrochloride | 10mM(in 1mL DMSO) | $57 | 2021-12-16 | Buy |
| ApexBio Technology | A3958 | Veliparibdihydrochloride | 5mg | $65 | 2021-12-16 | Buy |
| ApexBio Technology | A3958 | Veliparibdihydrochloride | 10mg | $85 | 2021-12-16 | Buy |
| ApexBio Technology | A3958 | Veliparibdihydrochloride | 50mg | $260 | 2021-12-16 | Buy |
| ApexBio Technology | A3958 | Veliparibdihydrochloride | 200mg | $678 | 2021-12-16 | Buy |
| Axon Medchem | Axon2888 | ABT888dihydrochloride-Veliparibdihydrochloride|A861695dihydrochloride 99% | 2x10mg | $154 | 2021-12-16 | Buy |
| Axon Medchem | Axon2888 | ABT888dihydrochloride-Veliparibdihydrochloride|A861695dihydrochloride 99% | 50mg | $313.5 | 2021-12-16 | Buy |
| Cayman Chemical | 11505 | ABT-888 (hydrochloride) ≥98% | 1mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 11505 | ABT-888 (hydrochloride) ≥98% | 5mg | $109 | 2024-03-01 | Buy |
| Cayman Chemical | 11505 | ABT-888 (hydrochloride) ≥98% | 10mg | $142 | 2024-03-01 | Buy |
| Cayman Chemical | 11505 | ABT-888 (hydrochloride) ≥98% | 25mg | $267 | 2024-03-01 | Buy |
| ChemScene | CS-0077 | Veliparibdihydrochloride 99.96% | 5mg | $60 | 2021-12-16 | Buy |
| ChemScene | CS-0077 | Veliparibdihydrochloride 99.96% | 10mg | $84 | 2021-12-16 | Buy |
Properties
Melting point :>173°C (dec.)
storage temp. :Refrigerator
solubility :Methanol (Slightly, Heated), THF (Slightly, Heated)
form :Colorless to white crystalline solid.
color :Off-White to Dark Yellow
storage temp. :Refrigerator
solubility :Methanol (Slightly, Heated), THF (Slightly, Heated)
form :Colorless to white crystalline solid.
color :Off-White to Dark Yellow
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
Poly(ADP-ribose) polymerases (PARPs) have diverse roles in cellular processes, including DNA repair and apoptosis. ABT-888 is an orally bioavailable inhibitor of PARP1 and PARP2 (Kis = 5.2 and 2.9 nM, respectively). It enhances apoptosis and autophagy in response to treatments that cause DNA breaks, including radiation and DNA alkylation. ABT-888 is an orally bioavailable inhibitor of PARP1 and PARP2 (Kis = 5.2 and 2.9 nM, respectively). It enhances apoptosis and autophagy in response to treatments that cause DNA breaks, including radiation and DNA alkylation. ABT-888 also acts synergistically with chemotherapies to increase the lethal effects of radiation in cancer cells.More related product prices
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