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ChemicalBook >> CAS DataBase List >> ARN14988

ARN14988

ARN14988 price.
  • $44 - $745
  • Product name: ARN14988
  • CAS: 1502027-70-4
  • MF: C16H24ClN3O5
  • MW: 373.83
  • EINECS:
  • MDL Number:
  • Synonyms:ARN14988;ARN398;ARN14988,ARN-14988;1(2H)-Pyrimidinecarboxylic acid, 5-chloro-3-[(hexylamino)carbonyl]-3,6-dihydro-2,6-dioxo-, 2-methylpropyl ester;5-chloro-3-[(hexylamino)carbonyl]-3,6-dihydro-2,6-dioxo-1(2H)-pyrimidinecarboxylicacid,2-methylpropylester
Price4 Properties Safety Information Description
4 prices
Selected condition：
Brand
  • Cayman Chemical
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • ManufacturerCayman Chemical
  • Product number24284
  • Product descriptionARN14988
  • Packaging1mg
  • Price$44
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number24284
  • Product descriptionARN14988
  • Packaging5mg
  • Price$193
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number24284
  • Product descriptionARN14988
  • Packaging10mg
  • Price$341
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number24284
  • Product descriptionARN14988
  • Packaging25mg
  • Price$745
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 24284 ARN14988 1mg $44 2024-03-01 Buy
Cayman Chemical 24284 ARN14988 5mg $193 2024-03-01 Buy
Cayman Chemical 24284 ARN14988 10mg $341 2024-03-01 Buy
Cayman Chemical 24284 ARN14988 25mg $745 2024-03-01 Buy

Properties

Density :1.27±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.33 mg/ml; Ethanol: slightly soluble
form :A crystalline solid
pka :7.89±0.40(Predicted)

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

ARN14988 is a potent inhibitor of acid ceramidase (IC50 = 12.8 nM for the human enzyme). It inhibits acid ceramidase activity and increases levels of C16 dihydro ceramide and C16 ceramide in A375, G361, M14, MeWo, MNT-1, and SK-MEL-28 melanoma cells. ARN14988 also reduces growth of A375 and G361 melanoma cells (EC50s = 41.8 and 67.7 μM, respectively).

Suppliers and manufacturers

TargetMol Chemicals Inc.
ARN14988
$110.00 /1mg
ARN14988 CAS:1502027-70-4
Shanghai EFE Biological Technology Co., Ltd. Shanghai Hongye Biotechnology Co. Ltd ChemeGen(Shanghai) Biotechnology Co.,Ltd. Changzhou Furuisi Biotechnology Co., Ltd Beijing Biocreative Technology Co., Ltd. Nanjing Tengyi Biotechnology Co., Ltd TargetMol Chemicals Inc.