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ChemicalBook >> CAS DataBase List >> AS1842856

AS1842856

AS1842856 price.
  • $31 - $1600
  • Product name: AS1842856
  • CAS: 836620-48-5
  • MF: C18H22FN3O3
  • MW: 347.38
  • EINECS:-0
  • MDL Number:
  • Synonyms:AS1842856;5-Amino-7-(cyclohexylamino)-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid;CS-2538;AS 1842856;AS-1842856;5-Amino-7-(cyclohexylamino)-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid;3-Quinolinecarboxylic acid, 5-amino-7-(cyclohexylamino)-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-
16 prices
Selected condition:
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • Axon Medchem
  • Cayman Chemical
  • DC Chemicals
  • Tocris
  • TRC
Package
  • 10
  • 1mg
  • 5mg
  • 10mg
  • 2x10mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number0436DW
  • Product description5-Amino-7-(cyclohexylamino)-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylicacid
  • Packaging10mg
  • Price$293
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA169136
  • Product descriptionAS-1842856 98+%
  • Packaging5mg
  • Price$73
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA169136
  • Product descriptionAS-1842856 98+%
  • Packaging10mg
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA169136
  • Product descriptionAS-1842856 98+%
  • Packaging50mg
  • Price$257
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA169136
  • Product descriptionAS-1842856 98+%
  • Packaging100mg
  • Price$334
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA169136
  • Product descriptionAS-1842856 98+%
  • Packaging250mg
  • Price$500
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0005726
  • Product descriptionAS-1842856 95.00%
  • Packaging5MG
  • Price$452.03
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2839
  • Product descriptionAS1842856 99%
  • Packaging10mg
  • Price$104.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2839
  • Product descriptionAS1842856 99%
  • Packaging2x10mg
  • Price$154
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2839
  • Product descriptionAS1842856 99%
  • Packaging50mg
  • Price$368.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number16761
  • Product descriptionAS-1842856 ≥98%
  • Packaging1mg
  • Price$31
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16761
  • Product descriptionAS-1842856 ≥98%
  • Packaging5mg
  • Price$77
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16761
  • Product descriptionAS-1842856 ≥98%
  • Packaging10mg
  • Price$108
  • Updated2024-03-01
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC10086
  • Product descriptionAS1842856 >98%
  • Packaging1g
  • Price$1600
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number4265
  • Product descriptionAS1842856 ≥98%(HPLC)
  • Packaging10
  • Price$95
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberA790073
  • Product descriptionAS1842856
  • Packaging10mg
  • Price$95
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 0436DW 5-Amino-7-(cyclohexylamino)-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylicacid 10mg $293 2021-12-16 Buy
Ambeed A169136 AS-1842856 98+% 5mg $73 2021-12-16 Buy
Ambeed A169136 AS-1842856 98+% 10mg $110 2021-12-16 Buy
Ambeed A169136 AS-1842856 98+% 50mg $257 2021-12-16 Buy
Ambeed A169136 AS-1842856 98+% 100mg $334 2021-12-16 Buy
Ambeed A169136 AS-1842856 98+% 250mg $500 2021-12-16 Buy
American Custom Chemicals Corporation INB0005726 AS-1842856 95.00% 5MG $452.03 2021-12-16 Buy
Axon Medchem Axon2839 AS1842856 99% 10mg $104.5 2021-12-16 Buy
Axon Medchem Axon2839 AS1842856 99% 2x10mg $154 2021-12-16 Buy
Axon Medchem Axon2839 AS1842856 99% 50mg $368.5 2021-12-16 Buy
Cayman Chemical 16761 AS-1842856 ≥98% 1mg $31 2024-03-01 Buy
Cayman Chemical 16761 AS-1842856 ≥98% 5mg $77 2024-03-01 Buy
Cayman Chemical 16761 AS-1842856 ≥98% 10mg $108 2024-03-01 Buy
DC Chemicals DC10086 AS1842856 >98% 1g $1600 2021-12-16 Buy
Tocris 4265 AS1842856 ≥98%(HPLC) 10 $95 2021-12-16 Buy
TRC A790073 AS1842856 10mg $95 2021-12-16 Buy

Properties

Boiling point :587.3±50.0 °C(Predicted)
Density :1.370±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :DMSO:5.0(Max Conc. mg/mL);14.39(Max Conc. mM)
form :A crystalline solid
pka :6.47±0.50(Predicted)
color :White to light yellow

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H372 Causes damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P314, P501
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P273 Avoid release to the environment.
P501 Dispose of contents/container to..…

Description

AS-1842856 is a potent inhibitor of forkhead box class O transcription factor 1 (FoxO1; IC50 = 33 nM in HepG2 cells). Inhibition of FoxO1-mediated transactivation with AS-1842856 leads to a dose-dependent decrease in expression of glucose-6 phosphatase (G6Pase) and phosphoenolpyruvate carboxykinase (PEPCK) mRNA and inhibits glucogenesis in rat hepatoma Fao cells and a murine model of type 2 diabetes mellitus (T2DM). AS-1842856 also inhibits 3T3-L1 preadipocyte differentiation and reduces lipid droplet growth in adipocytes.,

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