AZD6482(s)
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- $245 - $1491
- Product name: AZD6482(s)
- CAS: 1173900-37-2
- MF: C22H24N4O4
- MW: 408.45036
- EINECS:
- MDL Number:MFCD28053500
- Synonyms:AZD6482(s);AZD6482 (S-isomer);2-((S)-1-(7-Methyl-2-morpholino-4-oxo-4h-pyrido[1,2-a]pyrimidin-9-yl)ethylamino)benzoic acid;AZD6482 (S-ISOMER); AZD6482 (S); AZD6482; AZD-6482; AZD 6482.;AZD-6482 (S-isomer),AZD6482 (S isomer),AZD6482 (Sisomer);Benzoic acid, 2-[[(1S)-1-[7-methyl-2-(4-morpholinyl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl]ethyl]amino]-
4 prices
Selected condition：
Brand
- AK Scientific
- Biosynth Carbosynth
- Crysdot
Package
- 10mg
- 50mg
- 1g
- ManufacturerAK Scientific
- Product number7416DN
- Product description2-[[(1S)-1-(7-Methyl-2-morpholin-4-yl-4-oxopyrido[1,2-a]pyrimidin-9-yl)ethyl]amino]benzoicacid
- Packaging10mg
- Price$380
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA137653
- Product descriptionAZD 6482 (S isomer)
- Packaging10mg
- Price$245
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA137653
- Product descriptionAZD 6482 (S isomer)
- Packaging50mg
- Price$857.5
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD11341210
- Product descriptionAZD-6482 95+%
- Packaging1g
- Price$1491
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 7416DN | 2-[[(1S)-1-(7-Methyl-2-morpholin-4-yl-4-oxopyrido[1,2-a]pyrimidin-9-yl)ethyl]amino]benzoicacid | 10mg | $380 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA137653 | AZD 6482 (S isomer) | 10mg | $245 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA137653 | AZD 6482 (S isomer) | 50mg | $857.5 | 2021-12-16 | Buy |
| Crysdot | CD11341210 | AZD-6482 95+% | 1g | $1491 | 2021-12-16 | Buy |
Properties
Boiling point :635.5±65.0 °C(Predicted)
Density :1.36±0.1 g/cm3(Predicted)
pka :3.90±0.50(Predicted)
Density :1.36±0.1 g/cm3(Predicted)
pka :3.90±0.50(Predicted)
Safety Information
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Description
AZD6482 (S-isomer), CAS#1173900-37-2, is an isomer of AZD6482 (MedKoo Cat#406268) with S-configuration. AZD6482 is a potent, selective and ATP competitive PI3Kβ inhibitor (IC(50) 0.01 μm). AZD6482 inhibited insulin-induced human adipocyte glucose uptake in vitro (IC(50) of 4.4 μm). This is the first human target validation for PI3Kβ inhibition as anti-platelet therapy showing a mild and generalized antiplatelet effect attenuating but not completely inhibiting multiple signaling pathways with an impressive separation towards primary hemostasis. AZD6482 at 'supratherapeutic' plasma concentrations may attenuate insulin signaling, most likely through PI3Kα inhibition.Suppliers and manufacturers
Hebei Binshare New Material Co. Ltd
InvivoChem
TargetMol Chemicals Inc.
Amadis Chemical Company Limited
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.
Wuhan Sun-shine Bio-technology Corporation Limited
Nanjing Meihao Pharmaceutical Technology Co., Ltd.
Wuxi Donghe Pharmaceutical Technology Co., Ltd.
Absin Bioscience Inc.
