BAFILOMYCIN B1
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- $41 - $505
- Product name: BAFILOMYCIN B1
- CAS: 88899-56-3
- MF: C44H65NO13
- MW: 815.99
- EINECS:
- MDL Number:MFCD33021141
- Synonyms:BAFILOMYCIN B1;BAFILOMYCIN B1 MONOHYDRATE FROM STREPTO- MYCES SPECIES;BafilomycinB1fromStreptomycesgriseus;bafilomycin b1from streptomyces sp.;hygrolidin,37-decarboxy-2-demethyl-37-(((2-hydroxy-5-oxo-1-cyclopenten-1-yl)am ;ino)carbonyl)-2-methoxy-24-methyl- ;37-De(carboxy)-2-demethyl-37-[[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]carbonyl]-2-methoxy-24-methylhygrolidin;2-Butenoic acid, 4-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-4-oxo-, (2R,4R,5S,6R)-tetrahydro-2-hydroxy-2-[(1S,2R,3S)-2-hydroxy-3-[(2R,3S,4E,6E,9S,10S,11R,12E,14Z)-10-hydroxy-3,15-dimethoxy-7,9,11,13-tetramethyl-16-oxooxacyclohexadeca-4,6,12,14-tetraen-2-yl]-1-methylbutyl]-5-methyl-6-(1-methylethy...
9 prices
Selected condition：
Brand
- Adipogen Life Sciences
- Alfa Aesar
- Cayman Chemical
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 100ug
- 100μg
- 1mg
- 2.5mg
- 5mg
- 1ml
- ManufacturerAdipogen Life Sciences
- Product numberBVT-0004-C100
- Product descriptionBafilomycinB1 ≥97%(HPLC)
- Packaging100μg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ67463
- Product descriptionBafilomycin B1, 0.1 mg/ml in methanol, sterile-filtered
- Packaging1ml
- Price$321
- Updated2023-06-20
- Buy
- ManufacturerCayman Chemical
- Product number14005
- Product descriptionBafilomycin B1 ≥97%
- Packaging100μg
- Price$41
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14005
- Product descriptionBafilomycin B1 ≥97%
- Packaging1mg
- Price$142
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14005
- Product descriptionBafilomycin B1 ≥97%
- Packaging5mg
- Price$505
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product number11707
- Product descriptionBafilomycin B1 from Streptomyces sp. ≥80% (HPLC)
- Packaging1mg
- Price$218
- Updated2022-05-15
- Buy
- ManufacturerTRC
- Product numberB110005
- Product descriptionBafilomycinB1
- Packaging2.5mg
- Price$250
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number207084
- Product descriptionBafilomycin B1
- Packaging100ug
- Price$290
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product numberB0003-71
- Product descriptionBafilomycin B1
- Packaging1mg
- Price$368
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | BVT-0004-C100 | BafilomycinB1 ≥97%(HPLC) | 100μg | $50 | 2021-12-16 | Buy |
| Alfa Aesar | J67463 | Bafilomycin B1, 0.1 mg/ml in methanol, sterile-filtered | 1ml | $321 | 2023-06-20 | Buy |
| Cayman Chemical | 14005 | Bafilomycin B1 ≥97% | 100μg | $41 | 2024-03-01 | Buy |
| Cayman Chemical | 14005 | Bafilomycin B1 ≥97% | 1mg | $142 | 2024-03-01 | Buy |
| Cayman Chemical | 14005 | Bafilomycin B1 ≥97% | 5mg | $505 | 2024-03-01 | Buy |
| Sigma-Aldrich | 11707 | Bafilomycin B1 from Streptomyces sp. ≥80% (HPLC) | 1mg | $218 | 2022-05-15 | Buy |
| TRC | B110005 | BafilomycinB1 | 2.5mg | $250 | 2021-12-16 | Buy |
| Usbiological | 207084 | Bafilomycin B1 | 100ug | $290 | 2021-12-16 | Buy |
| Usbiological | B0003-71 | Bafilomycin B1 | 1mg | $368 | 2021-12-16 | Buy |
Properties
storage temp. :−20°C
solubility :DMSO: Soluble; Methanol: Unstable
form :powder or crystals
color :faint yellow to yellow
BRN :4640118
Stability :Hygroscopic
solubility :DMSO: Soluble; Methanol: Unstable
form :powder or crystals
color :faint yellow to yellow
BRN :4640118
Stability :Hygroscopic
Safety Information
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| Signal word: | Danger | ||||||||||
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Description
The bafilomycins are fungal plecomacrolide antibiotics with a 16-membered lactone ring. They inhibit the growth of Gram-positive bacteria and fungi. Bafilomycin B1 is a selective, reversible inhibitor of vacuolar H+-ATPases (V-ATPases), blocking these proton pumps in mammalian, plant, or fungal cells with an IC50 value in the 4-400 nM range. It is at least 1,000-fold less potent at most other types of ATPases. When used at 100 nM, the related macrolide bafilomycin A1 blocks V-ATPase-mediated acidification of lysosomes during autophagy, preventing protein degradation. Remarkably, at only 1 nM, both bafilomycin A1 or B1 dramatically attenuate chloroquine-induced apoptosis of neurons without altering autophagy.More related product prices
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