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BAFILOMYCIN B1

CAS No.
88899-56-3
Chemical Name:
BAFILOMYCIN B1
Synonyms
BAFILOMYCIN B1;BAFILOMYCIN B1 USP/EP/BP;ino)carbonyl)-2-methoxy-24-methyl-;bafilomycin b1from streptomyces sp.;BafilomycinB1fromStreptomycesgriseus;BAFILOMYCIN B1 MONOHYDRATE FROM STREPTO- MYCES SPECIES;hygrolidin,37-decarboxy-2-demethyl-37-(((2-hydroxy-5-oxo-1-cyclopenten-1-yl)am;37-De(carboxy)-2-demethyl-37-[[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]carbonyl]-2-methoxy-24-methylhygrolidin;2-Butenoic acid, 4-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-4-oxo-, (2R,4R,5S,6R)-tetrahydro-2-hydroxy-2-[(1S,2R,3S)-2-hydroxy-3-[(2R,3S,4E,6E,9S,10S,11R,12E,14Z)-10-hydroxy-3,15-dimethoxy-7,9,11,13-tetramethyl-16-oxooxacyclohexadeca-4,6,12,14-tetraen-2-yl]-1-methylbutyl]-5-methyl-6-(1-methylethy...
CBNumber:
CB4312754
Molecular Formula:
C44H65NO13
Molecular Weight:
815.99
MDL Number:
MFCD33021141
MOL File:
88899-56-3.mol
MSDS File:
SDS
Last updated:2023-06-08 09:02:12

BAFILOMYCIN B1 Properties

storage temp. −20°C
solubility DMSO: Soluble; Methanol: Unstable
form powder or crystals
color faint yellow to yellow
BRN 4640118
Stability Hygroscopic

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H300+H310+H330
Precautionary statements  P260-P262-P264-P280-P302+P352+P310-P304+P340+P310
Hazard Codes  T+
Risk Statements  26/27/28
Safety Statements  36/37/39-45
RIDADR  UN 3462 6.1/PG 1
WGK Germany  3
RTECS  NG8841000
10-21
HazardClass  3
HS Code  2941900000
NFPA 704
0
4 0

BAFILOMYCIN B1 price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 11707 Bafilomycin B1 from Streptomyces sp. ≥80% (HPLC) 88899-56-3 1mg $218 2022-05-15 Buy
Alfa Aesar J67463 Bafilomycin B1, 0.1 mg/ml in methanol, sterile-filtered 88899-56-3 1ml $321 2023-06-20 Buy
Cayman Chemical 14005 Bafilomycin B1 ≥97% 88899-56-3 100μg $41 2024-03-01 Buy
Cayman Chemical 14005 Bafilomycin B1 ≥97% 88899-56-3 1mg $142 2024-03-01 Buy
Cayman Chemical 14005 Bafilomycin B1 ≥97% 88899-56-3 5mg $505 2024-03-01 Buy
Product number Packaging Price Buy
11707 1mg $218 Buy
J67463 1ml $321 Buy
14005 100μg $41 Buy
14005 1mg $142 Buy
14005 5mg $505 Buy

BAFILOMYCIN B1 Chemical Properties,Uses,Production

Description

Bafilomycin B1 is a fungal metabolite that has been found in Streptomyces and has diverse biological activities. It inhibits the activity of rat liver lysosomal vacuolar H+-ATPase (V-ATPase) in a concentration-dependent manner. Bafilomycin B1 (10-1,000 nM) induces autophagosome accumulation in MCF-7 cells. It inhibits chloroquine-induced apoptosis in primary cerebellar granule neurons (CGNs) when used at a concentration of 1 nM. Bafilomycin B1 reduces viral genome copy numbers in the culture supernatant of Vero E6 cells infected with H1N1 influenza A.

Uses

Bafilomycin B1 is a member of a potent family of macrocyclic lactones. Bafilomycin B1 shares the same mode of action and activity as its more accessible A1 analogue. Bafilomycin B1 is broadly active against bacteria, fungi, insects, nematodes and protozoans. Bafilomycin B1 has attracted interest as a potential agent for treating osteoporosis.

BAFILOMYCIN B1 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 65)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250 1026@dideu.com China 26165 58
BOC Sciences
16314854226; +16314854226 inquiry@bocsci.com United States 19743 58
Hefei fuya biotechnology co. LTD 18096409024 sales02@foreversyn.com China 1974 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 94717 76
Guangzhou Isun Pharmaceutical Co., Ltd 020-39119399 18927568969 isunpharm@qq.com China 4428 55
Codow Chemical Co.,Ltd. 18620099427 amy@howeipharm.com China 17698 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9708 58
Shanghai Xilong Biochemical Technology Co., Ltd. 021-52907766-8042 China 9947 58
Lynnchem 86-(0)29-85992781 17792393971 info@lynnchem.com China 4587 58

View Lastest Price from BAFILOMYCIN B1 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
BAFILOMYCIN B1 USP/EP/BP pictures 2021-07-20 BAFILOMYCIN B1 USP/EP/BP
88899-56-3
US $1.10 / g 1g 99.9% 100 Tons Min Dideu Industries Group Limited
BAFILOMYCIN B1 BAFILOMYCIN B1 MONOHYDRATE FROM STREPTO- MYCES SPECIES BafilomycinB1fromStreptomycesgriseus bafilomycin b1from streptomyces sp. hygrolidin,37-decarboxy-2-demethyl-37-(((2-hydroxy-5-oxo-1-cyclopenten-1-yl)am ino)carbonyl)-2-methoxy-24-methyl- 37-De(carboxy)-2-demethyl-37-[[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]carbonyl]-2-methoxy-24-methylhygrolidin 2-Butenoic acid, 4-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-4-oxo-, (2R,4R,5S,6R)-tetrahydro-2-hydroxy-2-[(1S,2R,3S)-2-hydroxy-3-[(2R,3S,4E,6E,9S,10S,11R,12E,14Z)-10-hydroxy-3,15-dimethoxy-7,9,11,13-tetramethyl-16-oxooxacyclohexadeca-4,6,12,14-tetraen-2-yl]-1-methylbutyl]-5-methyl-6-(1-methylethy... BAFILOMYCIN B1 USP/EP/BP 88899-56-3 C44H65NO13 Antibiotics Antibiotics A-F Antibiotics A to Z BioChemical Antibiotic MacrolidesMore...Close... A - KAntibiotics Antibacterial Antibiotics A to Antibiotics A-FAntibiotics Antibiotics by Application AntifungalAntibiotics Antineoplastic and Immunosuppressive AntibioticsAntibiotics Chemical Structure Class Inhibits an EnzymeAntibiotics Mechanism of Action Spectrum of Activity