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ChemicalBook >> CAS DataBase List >> BAY 58-2667 hydrochloride

BAY 58-2667 hydrochloride

BAY 58-2667 hydrochloride price.
  • $57 - $5062.6
  • Product name: BAY 58-2667 hydrochloride
  • CAS: 646995-35-9
  • MF: C36H40ClNO5
  • MW: 602.17
  • EINECS:
  • MDL Number:MFCD28127267
  • Synonyms:Cinaciguat (hydrochloride);Cinaciguat HCl;4-[[(4-Carboxybutyl)[2-[2-[[4-(2-phenylethyl)phenyl]methoxy]phenyl]ethyl]amino]methyl]benzoic acid hydrochloride;BAY 58-2667 hydrochloride - Cinaciguat hydrochloride;Cinaciguat hydrochloride >=98% (HPLC)
20 prices
Selected condition:
Brand
  • Adipogen Life Sciences
  • AK Scientific
  • Axon Medchem
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Sigma-Aldrich
  • TRC
Package
  • 500μg
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 2x5mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3509-M001
  • Product descriptionBAY58-2667.hydrochloride ≥98%(NMR)
  • Packaging1mg
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number5005CR
  • Product descriptionCinaciguathydrochloride
  • Packaging1mg
  • Price$209
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2172
  • Product descriptionBAY58-2667hydrochloride-Cinaciguathydrochloride 99%
  • Packaging2x5mg
  • Price$198
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2172
  • Product descriptionBAY58-2667hydrochloride-Cinaciguathydrochloride 99%
  • Packaging25mg
  • Price$467.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb573010
  • Product descriptionCinaciguat (hydrochloride) >98%
  • Packaging100mg
  • Price$1356.6
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb573010
  • Product descriptionCinaciguat (hydrochloride) >98%
  • Packaging250mg
  • Price$2541.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb573010
  • Product descriptionCinaciguat (hydrochloride) >98%
  • Packaging1g
  • Price$5062.6
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number17468
  • Product descriptionCinaciguat (hydrochloride) ≥98%
  • Packaging500μg
  • Price$57
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17468
  • Product descriptionCinaciguat (hydrochloride) ≥98%
  • Packaging1mg
  • Price$100
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17468
  • Product descriptionCinaciguat (hydrochloride) ≥98%
  • Packaging5mg
  • Price$384
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17468
  • Product descriptionCinaciguat (hydrochloride) ≥98%
  • Packaging10mg
  • Price$547
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6013
  • Product descriptionCinaciguathydrochloride 99.64%
  • Packaging2mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6013
  • Product descriptionCinaciguathydrochloride 99.64%
  • Packaging5mg
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6013
  • Product descriptionCinaciguathydrochloride 99.64%
  • Packaging10mg
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6013
  • Product descriptionCinaciguathydrochloride 99.64%
  • Packaging50mg
  • Price$1080
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC12369
  • Product descriptionCinaciguat(hydrochloride) >98%
  • Packaging100mg
  • Price$900
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CR1-3509-M001 BAY58-2667.hydrochloride ≥98%(NMR) 1mg $75 2021-12-16 Buy
AK Scientific 5005CR Cinaciguathydrochloride 1mg $209 2021-12-16 Buy
Axon Medchem Axon2172 BAY58-2667hydrochloride-Cinaciguathydrochloride 99% 2x5mg $198 2021-12-16 Buy
Axon Medchem Axon2172 BAY58-2667hydrochloride-Cinaciguathydrochloride 99% 25mg $467.5 2021-12-16 Buy
Biorbyt Ltd orb573010 Cinaciguat (hydrochloride) >98% 100mg $1356.6 2021-12-16 Buy
Biorbyt Ltd orb573010 Cinaciguat (hydrochloride) >98% 250mg $2541.5 2021-12-16 Buy
Biorbyt Ltd orb573010 Cinaciguat (hydrochloride) >98% 1g $5062.6 2021-12-16 Buy
Cayman Chemical 17468 Cinaciguat (hydrochloride) ≥98% 500μg $57 2024-03-01 Buy
Cayman Chemical 17468 Cinaciguat (hydrochloride) ≥98% 1mg $100 2024-03-01 Buy
Cayman Chemical 17468 Cinaciguat (hydrochloride) ≥98% 5mg $384 2024-03-01 Buy
Cayman Chemical 17468 Cinaciguat (hydrochloride) ≥98% 10mg $547 2024-03-01 Buy
ChemScene CS-6013 Cinaciguathydrochloride 99.64% 2mg $120 2021-12-16 Buy
ChemScene CS-6013 Cinaciguathydrochloride 99.64% 5mg $180 2021-12-16 Buy
ChemScene CS-6013 Cinaciguathydrochloride 99.64% 10mg $300 2021-12-16 Buy
ChemScene CS-6013 Cinaciguathydrochloride 99.64% 50mg $1080 2021-12-16 Buy
DC Chemicals DC12369 Cinaciguat(hydrochloride) >98% 100mg $900 2021-12-16 Buy

Properties

storage temp. :-20°C
solubility :DMSO:66.74(Max Conc. mg/mL);110.83(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:1):0.5(Max Conc. mg/mL);0.83(Max Conc. mM)
DMF:30.0(Max Conc. mg/mL);49.82(Max Conc. mM)
Ethanol:5.0(Max Conc. mg/mL);8.3(Max Conc. mM) form :powder
color :white to beige

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Soluble guanylate cyclase (sGC) is the primary cellular receptor for NO. NO binds and activates a heme group in sGC, initiating the conversion of GTP to the second messenger cGMP. cGMP subsequently mediates a number of signaling cascades leading to vasorelaxation and inhibiting smooth muscle proliferation, leukocyte recruitment, and platelet aggregation. Oxidation of the heme results in its dissociation from sGC and an impairment of NO signaling, which has been linked to hypertension, hyperlidemia, cardiovascular disease, and diabetes. Cinaciguat is an activator of sGC that binds to a regulatory site, resulting in activation in an NO-independent manner (Kd = 3.2 nM). It activates the enzyme even if it has been oxidized or rendered heme deficient. In animals, cinaciguat has been shown to reduce hypertension, limit cardiomyocyte hypertrophy, protect against ischemia/reperfusion injury, and reduce morbidity and mortality in response to endotoxic shock.