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ChemicalBook >> CAS DataBase List >> BUTYROLACETONE 3

BUTYROLACETONE 3

BUTYROLACETONE 3 price.
  • $54 - $1315
  • Product name: BUTYROLACETONE 3
  • CAS: 778649-18-6
  • MF: C9H12O4
  • MW: 184.19
  • EINECS:
  • MDL Number:MFCD08702690
  • Synonyms:GCN5 INHIBITOR 1;BUTYROLACETONE 3;Butyrolactone 3;3-Furancarboxylic acid, tetrahydro-4-methylene-5-oxo-2-propyl-, (2R,3S)-rel-
12 prices
Selected condition:
Brand
  • Adipogen Life Sciences
  • AK Scientific
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • TRC
  • Usbiological
Package
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3522-M002
  • Product descriptionButyrolactone3 ≥95%(NMR)
  • Packaging2mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number5417CR
  • Product descriptionButyrolactone3
  • Packaging1mg
  • Price$154
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3209
  • Product descriptionButyrolactone3
  • Packaging1mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3209
  • Product descriptionButyrolactone3
  • Packaging5mg
  • Price$269
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number12095
  • Product descriptionButyrolactone 3 ≥95%
  • Packaging1mg
  • Price$54
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number12095
  • Product descriptionButyrolactone 3 ≥95%
  • Packaging5mg
  • Price$155
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0103268
  • Product descriptionButyrolactone3 ≥98.0%
  • Packaging5mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0103268
  • Product descriptionButyrolactone3 ≥98.0%
  • Packaging10mg
  • Price$400
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0103268
  • Product descriptionButyrolactone3 ≥98.0%
  • Packaging25mg
  • Price$780
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0103268
  • Product descriptionButyrolactone3 ≥98.0%
  • Packaging50mg
  • Price$1100
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberB761010
  • Product descriptionButyrolactone3
  • Packaging50mg
  • Price$1315
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number207098
  • Product descriptionButyrolactone 3
  • Packaging2mg
  • Price$325
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CR1-3522-M002 Butyrolactone3 ≥95%(NMR) 2mg $90 2021-12-16 Buy
AK Scientific 5417CR Butyrolactone3 1mg $154 2021-12-16 Buy
ApexBio Technology C3209 Butyrolactone3 1mg $60 2021-12-16 Buy
ApexBio Technology C3209 Butyrolactone3 5mg $269 2021-12-16 Buy
Cayman Chemical 12095 Butyrolactone 3 ≥95% 1mg $54 2024-03-01 Buy
Cayman Chemical 12095 Butyrolactone 3 ≥95% 5mg $155 2024-03-01 Buy
ChemScene CS-0103268 Butyrolactone3 ≥98.0% 5mg $250 2021-12-16 Buy
ChemScene CS-0103268 Butyrolactone3 ≥98.0% 10mg $400 2021-12-16 Buy
ChemScene CS-0103268 Butyrolactone3 ≥98.0% 25mg $780 2021-12-16 Buy
ChemScene CS-0103268 Butyrolactone3 ≥98.0% 50mg $1100 2021-12-16 Buy
TRC B761010 Butyrolactone3 50mg $1315 2021-12-16 Buy
Usbiological 207098 Butyrolactone 3 2mg $325 2021-12-16 Buy

Properties

storage temp. :-20°C
solubility :≤14mg/ml in ethanol;14mg/ml in DMSO;13mg/ml in dimethyl formamide
form :powder
color :white to off-white
Stability :Light Sensitive

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Gcn5 is a chromatin modifying factor whose HAT activity is required to acetylate histone H3 lysine 9 (K9) and K14, which facilitates transcription elongation by relaxing nucleosomes. Butyrolactone 3 specifically inhibits the histone acetyltransferase Gcn5 with an IC50 value of 100 μM and has an affinity to the Gcn5 enzyme comparable to that of its natural substrate, histone H3. Butyrolactone 3 can inhibit pre-RNA splicing with an IC50 value of 0.5 mM and as such has been used to investigate Gcn5/PCAF-like HAT functions during assembly of spliceosome before pre-mRNA translation.

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