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ChemicalBook >> CAS DataBase List >> CAY10416

CAY10416

CAY10416 price.
  • $57 - $953.22
  • Product name: CAY10416
  • CAS: 443919-96-8
  • MF: C29H29FN2O5S
  • MW: 536.61
  • EINECS:
  • MDL Number:MFCD12912357
  • Synonyms:CAY10416;3-[[3-fluoro-5-(tetrahydro-4-methoxy-2H-pyran-4-yl)phenoxy]methyl]-1-[4-(methylsulfonyl)phenyl]-5-phenyl-1H-pyrazole;1H-Pyrazole, 3-[[3-fluoro-5-(tetrahydro-4-methoxy-2H-pyran-4-yl)phenoxy]methyl]-1-[4-(methylsulfonyl)phenyl]-5-phenyl-;CAY10416,CAY-10416
8 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • TRC
Package
  • 1MG
  • 2.5mg
  • 5mg
  • 10MG
  • ManufacturerAK Scientific
  • Product number1381AH
  • Product description3-[[3-Fluoro-5-(tetrahydro-4-methoxy-2H-pyran-4-yl)phenoxy]methyl]-1-[4-(methylsulfonyl)phenyl]-5-phenyl-1H-pyrazole
  • Packaging5mg
  • Price$374
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000699
  • Product description3-[[3-FLUORO-5-(TETRAHYDRO-4-METHOXY-2H-PYRAN-4-YL)PHENOXY]METHYL]-1-[4-(METHYLSULFONYL)PHENYL]-5-PHENYL-1H-PYRAZOLE 95.00%
  • Packaging1MG
  • Price$160.65
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000699
  • Product description3-[[3-FLUORO-5-(TETRAHYDRO-4-METHOXY-2H-PYRAN-4-YL)PHENOXY]METHYL]-1-[4-(METHYLSULFONYL)PHENYL]-5-PHENYL-1H-PYRAZOLE 95.00%
  • Packaging5MG
  • Price$811.86
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000699
  • Product description3-[[3-FLUORO-5-(TETRAHYDRO-4-METHOXY-2H-PYRAN-4-YL)PHENOXY]METHYL]-1-[4-(METHYLSULFONYL)PHENYL]-5-PHENYL-1H-PYRAZOLE 95.00%
  • Packaging10MG
  • Price$953.22
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number70635
  • Product descriptionCAY10416 ≥95%
  • Packaging1mg
  • Price$57
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number70635
  • Product descriptionCAY10416 ≥95%
  • Packaging5mg
  • Price$249
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number70635
  • Product descriptionCAY10416 ≥95%
  • Packaging10mg
  • Price$437
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberB434815
  • Product description3-[[3-fluoro-5-(tetrahydro-4-methoxy-2H-pyran-4-yl)phenoxy]methyl]-1-[4-(methylsulfonyl)phenyl]-5-phenyl-1H-pyrazole
  • Packaging2.5mg
  • Price$155
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1381AH 3-[[3-Fluoro-5-(tetrahydro-4-methoxy-2H-pyran-4-yl)phenoxy]methyl]-1-[4-(methylsulfonyl)phenyl]-5-phenyl-1H-pyrazole 5mg $374 2021-12-16 Buy
American Custom Chemicals Corporation INB0000699 3-[[3-FLUORO-5-(TETRAHYDRO-4-METHOXY-2H-PYRAN-4-YL)PHENOXY]METHYL]-1-[4-(METHYLSULFONYL)PHENYL]-5-PHENYL-1H-PYRAZOLE 95.00% 1MG $160.65 2021-12-16 Buy
American Custom Chemicals Corporation INB0000699 3-[[3-FLUORO-5-(TETRAHYDRO-4-METHOXY-2H-PYRAN-4-YL)PHENOXY]METHYL]-1-[4-(METHYLSULFONYL)PHENYL]-5-PHENYL-1H-PYRAZOLE 95.00% 5MG $811.86 2021-12-16 Buy
American Custom Chemicals Corporation INB0000699 3-[[3-FLUORO-5-(TETRAHYDRO-4-METHOXY-2H-PYRAN-4-YL)PHENOXY]METHYL]-1-[4-(METHYLSULFONYL)PHENYL]-5-PHENYL-1H-PYRAZOLE 95.00% 10MG $953.22 2021-12-16 Buy
Cayman Chemical 70635 CAY10416 ≥95% 1mg $57 2024-03-01 Buy
Cayman Chemical 70635 CAY10416 ≥95% 5mg $249 2024-03-01 Buy
Cayman Chemical 70635 CAY10416 ≥95% 10mg $437 2024-03-01 Buy
TRC B434815 3-[[3-fluoro-5-(tetrahydro-4-methoxy-2H-pyran-4-yl)phenoxy]methyl]-1-[4-(methylsulfonyl)phenyl]-5-phenyl-1H-pyrazole 2.5mg $155 2021-12-16 Buy

Properties

storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 5 mg/ml
form :A crystalline solid

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Dual cyclooxygenase-2 (COX-2)/5-lipoxygenase (5-LO) inhibitors are potential therapeutic agents for inflammatory diseases and for prostate cancer. CAY10416 is a dual COX-2/5-LO inhibitor with IC50 values of 50 and 3 nM, respectively. The selectivity of CAY10416 for COX is greater than 200-fold for COX-2 versus COX-1. COX-2/5-LO inhibitors such as CAY10416 are also apoptosis-inducing agents and are potentially useful in prostate cancer chemotherapy. In the PC3 human carcinoma cell line, CAY10416 exhibits a 45% inhibition of proliferation at 100 μM. In the LNCaP human carcinoma cell line, CAY10416 inhibits growth with an IC50 value of 83 μM.