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CAY10416

CAY10416 Structure
CAY10416 structure
CAS No.
443919-96-8
Chemical Name:
CAY10416
Synonyms
CAY10416;CAY10416,CAY-10416;3-[[3-fluoro-5-(tetrahydro-4-methoxy-2H-pyran-4-yl)phenoxy]methyl]-1-[4-(methylsulfonyl)phenyl]-5-phenyl-1H-pyrazole;1H-Pyrazole, 3-[[3-fluoro-5-(tetrahydro-4-methoxy-2H-pyran-4-yl)phenoxy]methyl]-1-[4-(methylsulfonyl)phenyl]-5-phenyl-
CBNumber:
CB72590410
Molecular Formula:
C29H29FN2O5S
Molecular Weight:
536.61
MDL Number:
MFCD12912357
MOL File:
443919-96-8.mol
Last updated:2023-05-21 10:59:17
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CAY10416 Properties

storage temp. Store at -20°C
solubility DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 5 mg/ml
form A crystalline solid

CAY10416 price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 70635 CAY10416 ≥95% 443919-96-8 1mg $57 2024-03-01 Buy
Cayman Chemical 70635 CAY10416 ≥95% 443919-96-8 5mg $249 2024-03-01 Buy
Cayman Chemical 70635 CAY10416 ≥95% 443919-96-8 10mg $437 2024-03-01 Buy
TRC B434815 3-[[3-fluoro-5-(tetrahydro-4-methoxy-2H-pyran-4-yl)phenoxy]methyl]-1-[4-(methylsulfonyl)phenyl]-5-phenyl-1H-pyrazole 443919-96-8 2.5mg $155 2021-12-16 Buy
American Custom Chemicals Corporation INB0000699 3-[[3-FLUORO-5-(TETRAHYDRO-4-METHOXY-2H-PYRAN-4-YL)PHENOXY]METHYL]-1-[4-(METHYLSULFONYL)PHENYL]-5-PHENYL-1H-PYRAZOLE 95.00% 443919-96-8 1MG $160.65 2021-12-16 Buy
Product number Packaging Price Buy
70635 1mg $57 Buy
70635 5mg $249 Buy
70635 10mg $437 Buy
B434815 2.5mg $155 Buy
INB0000699 1MG $160.65 Buy

CAY10416 Chemical Properties,Uses,Production

Description

Dual cyclooxygenase-2 (COX-2)/5-lipoxygenase (5-LO) inhibitors are potential therapeutic agents for inflammatory diseases and for prostate cancer. CAY10416 is a dual COX-2/5-LO inhibitor with IC50 values of 50 and 3 nM, respectively. The selectivity of CAY10416 for COX is greater than 200-fold for COX-2 versus COX-1. COX-2/5-LO inhibitors such as CAY10416 are also apoptosis-inducing agents and are potentially useful in prostate cancer chemotherapy. In the PC3 human carcinoma cell line, CAY10416 exhibits a 45% inhibition of proliferation at 100 μM. In the LNCaP human carcinoma cell line, CAY10416 inhibits growth with an IC50 value of 83 μM.

Uses

3-[[3-fluoro-5-(tetrahydro-4-methoxy-2H-pyran-4-yl)phenoxy]methyl]-1-[4-(methylsulfonyl)phenyl]-5-phenyl-1H-pyrazole is a dual inhibitor of Cox-2 and 5-LO.

CAY10416 Preparation Products And Raw materials

Raw materials

Preparation Products

CAY10416 Suppliers

Global( 21)Suppliers
Supplier Tel Email Country ProdList Advantage
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44941 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24017 58
Shanghai Yiyan Biotechnology Co. , Ltd. 021-69985186 13611928337 3427709316@qq.com China 7984 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8740 58
Supplier Advantage
Aladdin Scientific 		58
Shanghai Hongye Biotechnology Co. Ltd 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Energy Chemical 58
TargetMol Chemicals Inc. 58
Shanghai Yiyan Biotechnology Co. , Ltd. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
CAY10416 3-[[3-fluoro-5-(tetrahydro-4-methoxy-2H-pyran-4-yl)phenoxy]methyl]-1-[4-(methylsulfonyl)phenyl]-5-phenyl-1H-pyrazole 1H-Pyrazole, 3-[[3-fluoro-5-(tetrahydro-4-methoxy-2H-pyran-4-yl)phenoxy]methyl]-1-[4-(methylsulfonyl)phenyl]-5-phenyl- CAY10416,CAY-10416 443919-96-8 C29H29FN2O5S