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CAY10416

CAY10416 구조식 이미지

카스 번호:: 443919-96-8

상품명:: CAY10416

동의어(영문):: CAY10416;CAY10416,CAY-10416;3-[[3-fluoro-5-(tetrahydro-4-methoxy-2H-pyran-4-yl)phenoxy]methyl]-1-[4-(methylsulfonyl)phenyl]-5-phenyl-1H-pyrazole;1H-Pyrazole, 3-[[3-fluoro-5-(tetrahydro-4-methoxy-2H-pyran-4-yl)phenoxy]methyl]-1-[4-(methylsulfonyl)phenyl]-5-phenyl-

CBNumber:: CB72590410

분자식:: C29H29FN2O5S

포뮬러 무게:: 536.61

MOL 파일:: 443919-96-8.mol

속성

안전

용도

공급 업체 21

CAY10416 속성

저장 조건: Store at -20°C

용해도: DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 5 mg/ml

물리적 상태: 결정성 고체

안전

CAY10416 C화학적 특성, 용도, 생산

개요

Dual cyclooxygenase-2 (COX-2)/5-lipoxygenase (5-LO) inhibitors are potential therapeutic agents for inflammatory diseases and for prostate cancer. CAY10416 is a dual COX-2/5-LO inhibitor with IC₅₀ values of 50 and 3 nM, respectively. The selectivity of CAY10416 for COX is greater than 200-fold for COX-2 versus COX-1. COX-2/5-LO inhibitors such as CAY10416 are also apoptosis-inducing agents and are potentially useful in prostate cancer chemotherapy. In the PC3 human carcinoma cell line, CAY10416 exhibits a 45% inhibition of proliferation at 100 μM. In the LNCaP human carcinoma cell line, CAY10416 inhibits growth with an IC₅₀ value of 83 μM.

CAY10416 준비 용품 및 원자재

원자재

준비 용품

CAY10416 공급 업체

글로벌( 21)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52927	58
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6870	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
Energy Chemical	021-58432009 400-005-6266	marketing@energy-chemical.com	China	44941	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	23963	58
Shanghai Yiyan Biotechnology Co. , Ltd.	021-69985186 13611928337	3427709316@qq.com	China	7980	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	8739	58