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ChemicalBook >> CAS DataBase List >> CAY10607

CAY10607

CAY10607 price.
  • $120 - $952
  • Product name: CAY10607
  • CAS: 1012788-65-6
  • MF: C19H20ClN3O4
  • MW: 389.83
  • EINECS:
  • MDL Number:MFCD18382085
  • Synonyms:CAY10607;Benzisoxazole Hsp90 Inhibitor;CAY10607 Exclusive;1,3-Benzenediol, 4-chloro-6-[5-[[2-(4-morpholinyl)ethyl]amino]-1,2-benzisoxazol-3-yl]-
5 prices
Selected condition:
Brand
  • AK Scientific
  • Cayman Chemical
  • TRC
Package
  • 1mg
  • 2.5mg
  • 5mg
  • 10mg
  • ManufacturerAK Scientific
  • Product number1409AH
  • Product description4-Chloro-6-(5-((2-(4-morpholinyl)ethyl)amino)-1,2-benzisoxazol-3-yl)-1,3-benzenediol
  • Packaging5mg
  • Price$695
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10012694
  • Product descriptionBenzisoxazole Hsp90 Inhibitor ≥98%
  • Packaging1mg
  • Price$120
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10012694
  • Product descriptionBenzisoxazole Hsp90 Inhibitor ≥98%
  • Packaging5mg
  • Price$537
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10012694
  • Product descriptionBenzisoxazole Hsp90 Inhibitor ≥98%
  • Packaging10mg
  • Price$952
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberB201968
  • Product descriptionBenzisoxazoleHsp90Inhibitor
  • Packaging2.5mg
  • Price$340
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1409AH 4-Chloro-6-(5-((2-(4-morpholinyl)ethyl)amino)-1,2-benzisoxazol-3-yl)-1,3-benzenediol 5mg $695 2021-12-16 Buy
Cayman Chemical 10012694 Benzisoxazole Hsp90 Inhibitor ≥98% 1mg $120 2024-03-01 Buy
Cayman Chemical 10012694 Benzisoxazole Hsp90 Inhibitor ≥98% 5mg $537 2024-03-01 Buy
Cayman Chemical 10012694 Benzisoxazole Hsp90 Inhibitor ≥98% 10mg $952 2024-03-01 Buy
TRC B201968 BenzisoxazoleHsp90Inhibitor 2.5mg $340 2021-12-16 Buy

Properties

storage temp. :Store at -20°C
solubility :DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 25 mg/ml; Ethanol:PBS (pH 7.2) (1:10): 0.1 mg/ml
form :A crystalline solid

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Heat shock protein 90 (Hsp90) is a molecular chaperone that modulates intracellular signaling and protein folding, trafficking, and turnover. Inhibitors of Hsp90, such as geldanamycin, have shown potential as anti-tumor agents. Benzisoxazole Hsp90 Inhibitor binds the N-terminal domain of Hsp90, efficiently displacing geldanamycin from the ATP binding site (IC50 = 30 nM). It also inhibits the proliferation of several cancer cell lines (IC50~ 0.28 μM), promotes the degradation of the Hsp90 client proteins Her-2 and androgen receptor, and has no effect on a variety of kinases.