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ChemicalBook >> CAS DataBase List >> CAY10625

CAY10625

CAY10625 price.
  • $65 - $812
  • Product name: CAY10625
  • CAS: 137346-42-0
  • MF: C25H26N4O4
  • MW: 446.5
  • EINECS:
  • MDL Number:
  • Synonyms:CAY10625;7-nitro-10-octyl-3-phenylpyrimido[4,5-b]quinoline-2,4-dione;Pyrimido[4,5-b]quinoline-2,4(3H,10H)-dione, 7-nitro-10-octyl-3-phenyl-
7 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • TRC
Package
  • 1mg
  • 2.5mg
  • 5MG
  • 10mg
  • ManufacturerAK Scientific
  • Product number1495AH
  • Product description7-Nitro-10-octyl-3-phenyl-pyrimido[4,5-B]quinoline-2,4(3H,10H)-dione
  • Packaging10mg
  • Price$812
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0151428
  • Product description7-NITRO-10-OCTYL-3-PHENYL-PYRIMIDO(4,5-B)QUINOLINE-2,4(3H,10H)-DIONE 95.00%
  • Packaging5MG
  • Price$499.33
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number13836
  • Product descriptionCAY10625 ≥95%
  • Packaging1mg
  • Price$82
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13836
  • Product descriptionCAY10625 ≥95%
  • Packaging5mg
  • Price$362
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13836
  • Product descriptionCAY10625 ≥95%
  • Packaging10mg
  • Price$642
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberN497008
  • Product description7-nitro-10-octyl-3-phenyl-pyrimido[4,5-b]quinoline-2,4(3H,10H)-dione
  • Packaging1mg
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberN497008
  • Product description7-nitro-10-octyl-3-phenyl-pyrimido[4,5-b]quinoline-2,4(3H,10H)-dione
  • Packaging2.5mg
  • Price$130
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1495AH 7-Nitro-10-octyl-3-phenyl-pyrimido[4,5-B]quinoline-2,4(3H,10H)-dione 10mg $812 2021-12-16 Buy
American Custom Chemicals Corporation CHM0151428 7-NITRO-10-OCTYL-3-PHENYL-PYRIMIDO(4,5-B)QUINOLINE-2,4(3H,10H)-DIONE 95.00% 5MG $499.33 2021-12-16 Buy
Cayman Chemical 13836 CAY10625 ≥95% 1mg $82 2024-03-01 Buy
Cayman Chemical 13836 CAY10625 ≥95% 5mg $362 2024-03-01 Buy
Cayman Chemical 13836 CAY10625 ≥95% 10mg $642 2024-03-01 Buy
TRC N497008 7-nitro-10-octyl-3-phenyl-pyrimido[4,5-b]quinoline-2,4(3H,10H)-dione 1mg $65 2021-12-16 Buy
TRC N497008 7-nitro-10-octyl-3-phenyl-pyrimido[4,5-b]quinoline-2,4(3H,10H)-dione 2.5mg $130 2021-12-16 Buy

Properties

storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 0.5 mg/ml
form :A crystalline solid

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Survivin is a cellular protein implicated in cell survival by interacting with and inhibiting the apoptotic function of several proteins including Smac/Diablo, caspase-3, and caspase-7. Survivin also plays a role in the regulation of the cell cycle as part of a protein complex that includes INCENP, Aurora B kinase, and Borealin. CAY10625 is an antagonist of the interaction between survivin and the apoptosis-promoting protein Smac/Diablo, exhibiting an IC50 value of 2.2 μM. It inhibits the interaction of survivin with INCENP less effectively with an IC50 value of 20 μM. CAY10625 is cell-permeable and sensitizes cells to the induction of apoptosis by doxorubicin.