CCG-1423
- $49 - $1600
- Product name: CCG-1423
- CAS: 285986-88-1
- MF: C18H13ClF6N2O3
- MW: 454.75
- EINECS:
- MDL Number:MFCD01566719
- Synonyms:CCG-1423;N-(2-(4-Chloroanilino)-1-Methyl-2-oxoethoxy)-3,5-bis(trifluoroMethyl)benzaMide;N-(1-(4-chlorophenylaMino)-1-oxopropan-2-yloxy)-3,5-bis(trifluoroMethyl)benzaMide;N-({1-[(4-Chlorophenyl)Amino]-1-Oxo-2-Propanyl}Oxy)-3,5-Bis(Trifluoromethyl)Benzamide CCG-1423;N-[2-[(4-Chlorophenyl)amino]-1-methyl-2-oxoethoxy]-3,5-bis(trifluoromethyl)-benzamide;N-[1-(4-chloroanilino)-1-oxopropan-2-yl]oxy-3,5-bis(trifluoromethyl)benzamide;Rho/SRF Pathway Inhibitor, CCG-1423 ;CCG-1423 USP/EP/BP
34 prices
Selected condition:
Brand
- AK Scientific
- Ambeed
- ApexBio Technology
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 10
- 50mg
- 100MG
- 50
- 5mg
- 10mg
- 25mg
- 10mM(in 1mL DMSO)
- 200mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product numberSYN5014
- Product descriptionCCG-1423
- Packaging50mg
- Price$357
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA381687
- Product descriptionCCG-1423 98+%
- Packaging5mg
- Price$104
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA381687
- Product descriptionCCG-1423 98+%
- Packaging10mg
- Price$156
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA381687
- Product descriptionCCG-1423 98+%
- Packaging50mg
- Price$344
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA381687
- Product descriptionCCG-1423 98+%
- Packaging250mg
- Price$580
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4897
- Product descriptionCCG-1423
- Packaging10mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4897
- Product descriptionCCG-1423
- Packaging10mM(in 1mL DMSO)
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4897
- Product descriptionCCG-1423
- Packaging50mg
- Price$165
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4897
- Product descriptionCCG-1423
- Packaging200mg
- Price$450
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number10010350
- Product descriptionCCG-1423 ≥98%
- Packaging5mg
- Price$49
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10010350
- Product descriptionCCG-1423 ≥98%
- Packaging10mg
- Price$82
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10010350
- Product descriptionCCG-1423 ≥98%
- Packaging25mg
- Price$179
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10010350
- Product descriptionCCG-1423 ≥98%
- Packaging50mg
- Price$286
- Updated2024-03-01
- Buy
- ManufacturerChem-Impex
- Product number42453
- Product descriptionCCG-1423,≥98%(HPLC) ≥98%(HPLC)
- Packaging25MG
- Price$218.98
- Updated2021-12-16
- Buy
- ManufacturerChem-Impex
- Product number42453
- Product descriptionCCG-1423,98%(HPLC) 98%(HPLC)
- Packaging100MG
- Price$677.6
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3689
- Product descriptionCCG-1423 99.94%
- Packaging10mg
- Price$60
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | SYN5014 | CCG-1423 | 50mg | $357 | 2021-12-16 | Buy |
Ambeed | A381687 | CCG-1423 98+% | 5mg | $104 | 2021-12-16 | Buy |
Ambeed | A381687 | CCG-1423 98+% | 10mg | $156 | 2021-12-16 | Buy |
Ambeed | A381687 | CCG-1423 98+% | 50mg | $344 | 2021-12-16 | Buy |
Ambeed | A381687 | CCG-1423 98+% | 250mg | $580 | 2021-12-16 | Buy |
ApexBio Technology | B4897 | CCG-1423 | 10mg | $50 | 2021-12-16 | Buy |
ApexBio Technology | B4897 | CCG-1423 | 10mM(in 1mL DMSO) | $50 | 2021-12-16 | Buy |
ApexBio Technology | B4897 | CCG-1423 | 50mg | $165 | 2021-12-16 | Buy |
ApexBio Technology | B4897 | CCG-1423 | 200mg | $450 | 2021-12-16 | Buy |
Cayman Chemical | 10010350 | CCG-1423 ≥98% | 5mg | $49 | 2024-03-01 | Buy |
Cayman Chemical | 10010350 | CCG-1423 ≥98% | 10mg | $82 | 2024-03-01 | Buy |
Cayman Chemical | 10010350 | CCG-1423 ≥98% | 25mg | $179 | 2024-03-01 | Buy |
Cayman Chemical | 10010350 | CCG-1423 ≥98% | 50mg | $286 | 2024-03-01 | Buy |
Chem-Impex | 42453 | CCG-1423,≥98%(HPLC) ≥98%(HPLC) | 25MG | $218.98 | 2021-12-16 | Buy |
Chem-Impex | 42453 | CCG-1423,98%(HPLC) 98%(HPLC) | 100MG | $677.6 | 2021-12-16 | Buy |
ChemScene | CS-3689 | CCG-1423 99.94% | 10mg | $60 | 2021-12-16 | Buy |
Properties
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: soluble5mg/mL, clear (warmed)
form :White solid
color :white to beige
solubility :DMSO: soluble5mg/mL, clear (warmed)
form :White solid
color :white to beige
Safety Information
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Signal word: | Warning | |||||||||||||||||||||
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Description
CCG-1423 is a specific inhibitor of Rho pathway-mediated signalling and activation of serum response factor (SRF) transcription. The Rho family of small GTPases play a vital role in transduction of cell signalling events associated with several human cancers. It inhibits SRF-driven luciferase expression in PC-3 cells following stimulation with constitutively active Gα13 with an IC50 value of 1 μM. The site of inhibition in the pathway is not precisely defined but CCG-1423 appears to act on some aspect of the interaction of SRF with its transcriptional cofactor megakaryoblastic leukemia 1 (MKL1) at a point upstream of DNA binding. CCG-1423 selectively inhibits DNA synthesis, proliferation and invasion of Rho-overexpressing cell lines at nanomolar to low micromolar concentrations.Related product price
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$1.00 /1KG
N-[1-(4-chloroanilino)-1-oxopropan-2-yl]oxy-3,5-bis(trifluoromethyl)benzamide CAS:285986-88-1
N-[1-(4-chloroanilino)-1-oxopropan-2-yl]oxy-3,5-bis(trifluoromethyl)benzamide CAS:285986-88-1