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ChemicalBook >> CAS DataBase List >> CITCO

CITCO

CITCO price.
  • $72 - $1041.76
  • Product name: CITCO
  • CAS: 338404-52-7
  • MF: C19H12Cl3N3OS
  • MW: 436.74
  • EINECS:
  • MDL Number:MFCD00139608
  • Synonyms:Imidazo[2,1-b]thiazole-5-carboxaldehyde, 6-(4-chlorophenyl)-, O-[(3,4-dichlorophenyl)methyl]oxime;6-(4-Chlorophenyl)imidazo[2,1-b]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl) oxime;CITCO,Inhibitor,inhibit,Apoptosis
Price15 Properties Safety Information Description
15 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • Sigma-Aldrich
  • TRC
Package
  • 1mg
  • 5MG
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • ManufacturerAK Scientific
  • Product number3614BB
  • Product descriptionCitco
  • Packaging10mg
  • Price$248
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1167756
  • Product description6-(4-Chlorophenyl)imidazo[2,1-b]thiazole-5-carbaldehydeO-(3,4-dichlorobenzyl)oxime 98%
  • Packaging25mg
  • Price$122
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1167756
  • Product description6-(4-Chlorophenyl)imidazo[2,1-b]thiazole-5-carbaldehydeO-(3,4-dichlorobenzyl)oxime 98%
  • Packaging50mg
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1167756
  • Product description6-(4-Chlorophenyl)imidazo[2,1-b]thiazole-5-carbaldehydeO-(3,4-dichlorobenzyl)oxime 98%
  • Packaging100mg
  • Price$280
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008469
  • Product descriptionCITCO 95.00%
  • Packaging5MG
  • Price$184.8
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008469
  • Product descriptionCITCO 95.00%
  • Packaging10MG
  • Price$660.95
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008469
  • Product descriptionCITCO 95.00%
  • Packaging50MG
  • Price$1041.76
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7468
  • Product descriptionCITCO
  • Packaging5mg
  • Price$81
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7468
  • Product descriptionCITCO
  • Packaging10mg
  • Price$152
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7468
  • Product descriptionCITCO
  • Packaging25mg
  • Price$342
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number16027
  • Product descriptionCITCO ≥95%
  • Packaging5mg
  • Price$72
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16027
  • Product descriptionCITCO ≥95%
  • Packaging10mg
  • Price$135
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16027
  • Product descriptionCITCO ≥95%
  • Packaging25mg
  • Price$301
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberC6240
  • Product descriptionCITCO ≥98% (HPLC), solid
  • Packaging5mg
  • Price$135
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberC433048
  • Product descriptionCITCO
  • Packaging1mg
  • Price$75
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3614BB Citco 10mg $248 2021-12-16 Buy
Ambeed A1167756 6-(4-Chlorophenyl)imidazo[2,1-b]thiazole-5-carbaldehydeO-(3,4-dichlorobenzyl)oxime 98% 25mg $122 2021-12-16 Buy
Ambeed A1167756 6-(4-Chlorophenyl)imidazo[2,1-b]thiazole-5-carbaldehydeO-(3,4-dichlorobenzyl)oxime 98% 50mg $200 2021-12-16 Buy
Ambeed A1167756 6-(4-Chlorophenyl)imidazo[2,1-b]thiazole-5-carbaldehydeO-(3,4-dichlorobenzyl)oxime 98% 100mg $280 2021-12-16 Buy
American Custom Chemicals Corporation API0008469 CITCO 95.00% 5MG $184.8 2021-12-16 Buy
American Custom Chemicals Corporation API0008469 CITCO 95.00% 10MG $660.95 2021-12-16 Buy
American Custom Chemicals Corporation API0008469 CITCO 95.00% 50MG $1041.76 2021-12-16 Buy
ApexBio Technology B7468 CITCO 5mg $81 2021-12-16 Buy
ApexBio Technology B7468 CITCO 10mg $152 2021-12-16 Buy
ApexBio Technology B7468 CITCO 25mg $342 2021-12-16 Buy
Cayman Chemical 16027 CITCO ≥95% 5mg $72 2024-03-01 Buy
Cayman Chemical 16027 CITCO ≥95% 10mg $135 2024-03-01 Buy
Cayman Chemical 16027 CITCO ≥95% 25mg $301 2024-03-01 Buy
Sigma-Aldrich C6240 CITCO ≥98% (HPLC), solid 5mg $135 2024-03-01 Buy
TRC C433048 CITCO 1mg $75 2021-12-16 Buy

Properties

Density :1.48±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: 28 mg/mL, soluble
form :solid
pka :4.05±0.40(Predicted)
color :Light yellow to yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

The constitutive androstane receptor (CAR) is a nuclear receptor that functions as a sensor of toxic compounds and enhances their elimination. CITCO is an agonist of human CAR (EC50 = 49 nM). It induces nuclear translocation of human CAR in hepatocytes, followed by increased expression of CAR-regulated genes, including several cytochrome P450 isoforms. CITCO less potently activates human pregnane X receptor (EC50 = 3 μM) and has no detectable activity on other nuclear receptors at 10 μM. It is selective for human CAR, whereas TCPOBOP is selective for mouse CAR. CITCO does activate alternative splice variants of human CAR that are also found in liver cells. It is commonly used to study the action of human CAR in hepatocytes.

Suppliers and manufacturers

ATK CHEMICAL COMPANY LIMITED
TargetMol Chemicals Inc.
LEAPCHEM CO., LTD.
Aladdin Scientific ShangHai Caerulum Pharma Discovery Co., Ltd. Sigma-Aldrich EMMX Biotechnology LLC Shanghai EFE Biological Technology Co., Ltd. ShangHai Biochempartner Co.,Ltd Shanghai Rechem science Co., Ltd.