COMPOUND 401
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- $24 - $1600
- Product name: COMPOUND 401
- CAS: 168425-64-7
- MF: C16H15N3O2
- MW: 281.31
- EINECS:
- MDL Number:MFCD10568147
- Synonyms:2-(4-Morpholinyl)-4H-pyrimido[2,1-a]isoquinolin-4-one;4H-PyriMido[2,1-a]isoquinolin-4-one, 2-(4-Morpholinyl)-;2-(Morpholin-4-yl)pyrimido[2,1-a]isoquinolin-4-one;2-Morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one;Compound 401, >=98%;2-Morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one;CS-315;COMPOUND401;COMPOUND-401
29 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- DC Chemicals
- TCI Chemical
- TRC
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number5139CR
- Product description2-Morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one
- Packaging1mg
- Price$133
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number5139CR
- Product description2-Morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one
- Packaging25mg
- Price$479
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA279135
- Product descriptionCompound401 98+%
- Packaging5mg
- Price$24
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA279135
- Product descriptionCompound401 98+%
- Packaging10mg
- Price$31
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA279135
- Product descriptionCompound401 98+%
- Packaging25mg
- Price$40
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA279135
- Product descriptionCompound401 98+%
- Packaging50mg
- Price$52
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA279135
- Product descriptionCompound401 98+%
- Packaging100mg
- Price$67
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA279135
- Product descriptionCompound401 98+%
- Packaging250mg
- Price$132
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA279135
- Product descriptionCompound401 98+%
- Packaging1g
- Price$331
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000312
- Product description2-(MORPHOLIN-1-YL)PYRIMIDO[2,1-A]ISOQUINOLIN-4-ONE 95.00%
- Packaging10MG
- Price$530
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000312
- Product description2-(MORPHOLIN-1-YL)PYRIMIDO[2,1-A]ISOQUINOLIN-4-ONE 95.00%
- Packaging50MG
- Price$1267.33
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7337
- Product descriptionCompound401
- Packaging100mg
- Price$1418
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number21769
- Product descriptionCompound 401
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21769
- Product descriptionCompound 401
- Packaging5mg
- Price$116
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21769
- Product descriptionCompound 401
- Packaging10mg
- Price$153
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21769
- Product descriptionCompound 401
- Packaging25mg
- Price$343
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 5139CR | 2-Morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one | 1mg | $133 | 2021-12-16 | Buy |
| AK Scientific | 5139CR | 2-Morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one | 25mg | $479 | 2021-12-16 | Buy |
| Ambeed | A279135 | Compound401 98+% | 5mg | $24 | 2021-12-16 | Buy |
| Ambeed | A279135 | Compound401 98+% | 10mg | $31 | 2021-12-16 | Buy |
| Ambeed | A279135 | Compound401 98+% | 25mg | $40 | 2021-12-16 | Buy |
| Ambeed | A279135 | Compound401 98+% | 50mg | $52 | 2021-12-16 | Buy |
| Ambeed | A279135 | Compound401 98+% | 100mg | $67 | 2021-12-16 | Buy |
| Ambeed | A279135 | Compound401 98+% | 250mg | $132 | 2021-12-16 | Buy |
| Ambeed | A279135 | Compound401 98+% | 1g | $331 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000312 | 2-(MORPHOLIN-1-YL)PYRIMIDO[2,1-A]ISOQUINOLIN-4-ONE 95.00% | 10MG | $530 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000312 | 2-(MORPHOLIN-1-YL)PYRIMIDO[2,1-A]ISOQUINOLIN-4-ONE 95.00% | 50MG | $1267.33 | 2021-12-16 | Buy |
| ApexBio Technology | B7337 | Compound401 | 100mg | $1418 | 2021-12-16 | Buy |
| Cayman Chemical | 21769 | Compound 401 | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 21769 | Compound 401 | 5mg | $116 | 2024-03-01 | Buy |
| Cayman Chemical | 21769 | Compound 401 | 10mg | $153 | 2024-03-01 | Buy |
| Cayman Chemical | 21769 | Compound 401 | 25mg | $343 | 2024-03-01 | Buy |
Properties
Melting point :184-186℃ (ethanol )
Boiling point :456.9±55.0 °C(Predicted)
Density :1.36±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. :Store at RT
solubility :DMSO : 6 mg/mL (21.33 mM; Need ultrasonic and warming)
pka :1.01±0.20(Predicted)
form :powder to crystal
color :White to Light yellow
CAS DataBase Reference :168425-64-7
Boiling point :456.9±55.0 °C(Predicted)
Density :1.36±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. :Store at RT
solubility :DMSO : 6 mg/mL (21.33 mM; Need ultrasonic and warming)
pka :1.01±0.20(Predicted)
form :powder to crystal
color :White to Light yellow
CAS DataBase Reference :168425-64-7
Safety Information
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Description
Compound 401 is a cell-permeable pyrimido-isoquinolinone compound that acts as a potent, reversible, and ATP-competitive inhibitor of DNA-PK (IC50 = 280 nM) with ~19-fold selectivity over mTOR (FRAP) (IC50 = 5.3 μM). Compound 401 exhibits much reduced or no activity against 43 other commonly studied kinases, including PI 3-K, ATM, and ATR. Compound 401 has been shown to induce apoptosis and inhibit FRAP-dependent growth in TSC1-/- murine embryo fibroblasts.More related product prices
Related product price
- COMPOUND 401
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