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ChemicalBook >> CAS DataBase List >> CP-547632

CP-547632

CP-547632 price.
  • $57 - $6683
  • Product name: CP-547632
  • CAS: 252003-65-9
  • MF: C20H24BrF2N5O3S
  • MW: 532.4
  • EINECS:200-258-5
  • MDL Number:MFCD07772279
  • Synonyms:CP-547632;3-(4-Bromo-2,6-difluorobenzyloxy)-5-(3-(4-pyrrolidin-1-ylbutyl)ureido)isothiazole-4-carboxylic acid amide;4-Isothiazolecarboxamide, 3-((4-bromo-2,6-difluorophenyl)methoxy)-5-((((4-(1-pyrrolidinyl)butyl)amino)carbonyl)amino)-;CP-547632(CP 547632);3-[(4-broMo-2,6-difluorophenyl)Methoxy]-5-[[[[4-(1-pyrrolidinyl)butyl]aMino]carbonyl]aMino]-4-isothiazolecarboxaMide;3-((4-Bromo-2,6-difluorobenzyl)oxy)-5-(3-(4-(pyrrolidin-1-yl)butyl)ureido)isothiazole-4-carboxami;3-((4-Bromo-2,6-difluorobenzyl)oxy)-5-(3-(4-(pyrrolidin-1-yl)butyl)ureido)isothiazole-4-carbox;3-[(4-Bromo-2,6-difluorobenzyl)oxy]-5-[3-[4-(pyrrolidin-1-yl)butyl]ureido]isothiazole-4-carboxamide
24 prices
Selected condition:
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
Package
  • 500μg
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 500MG
  • 1g
  • ManufacturerAK Scientific
  • Product numberX5494
  • Product description3-(4-Bromo-2,6-difluorobenzyloxy)-5-(3-(4-pyrrolidin-1-ylbutyl)ureido)isothiazole-4-carboxylicacidamide
  • Packaging250mg
  • Price$6683
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA867793
  • Product descriptionCp-547632 95%
  • Packaging5mg
  • Price$105
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA867793
  • Product descriptionCp-547632 95%
  • Packaging10mg
  • Price$137
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA867793
  • Product descriptionCp-547632 95%
  • Packaging25mg
  • Price$179
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA867793
  • Product descriptionCp-547632 95%
  • Packaging50mg
  • Price$284
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0005167
  • Product descriptionCP-547632 95.00%
  • Packaging500MG
  • Price$4966.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB102944
  • Product description3-[(4-Bromo-2,6-difluorobenzyl)oxy]-5-[3-[4-(pyrrolidin-1-yl)butyl]ureido]isothiazole-4-carboxamide
  • Packaging1mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB102944
  • Product description3-[(4-Bromo-2,6-difluorobenzyl)oxy]-5-[3-[4-(pyrrolidin-1-yl)butyl]ureido]isothiazole-4-carboxamide
  • Packaging2mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB102944
  • Product description3-[(4-Bromo-2,6-difluorobenzyl)oxy]-5-[3-[4-(pyrrolidin-1-yl)butyl]ureido]isothiazole-4-carboxamide
  • Packaging5mg
  • Price$220
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB102944
  • Product description3-[(4-Bromo-2,6-difluorobenzyl)oxy]-5-[3-[4-(pyrrolidin-1-yl)butyl]ureido]isothiazole-4-carboxamide
  • Packaging10mg
  • Price$400
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB102944
  • Product description3-[(4-Bromo-2,6-difluorobenzyl)oxy]-5-[3-[4-(pyrrolidin-1-yl)butyl]ureido]isothiazole-4-carboxamide
  • Packaging25mg
  • Price$750
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number21773
  • Product descriptionCP 547,632 ≥98%
  • Packaging500μg
  • Price$57
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21773
  • Product descriptionCP 547,632 ≥98%
  • Packaging1mg
  • Price$107
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21773
  • Product descriptionCP 547,632 ≥98%
  • Packaging5mg
  • Price$437
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM280772
  • Product descriptionCP-547632 98%
  • Packaging100mg
  • Price$1312
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0003189
  • Product descriptionCP-547632 >99.0%
  • Packaging5mg
  • Price$95
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific X5494 3-(4-Bromo-2,6-difluorobenzyloxy)-5-(3-(4-pyrrolidin-1-ylbutyl)ureido)isothiazole-4-carboxylicacidamide 250mg $6683 2021-12-16 Buy
Ambeed A867793 Cp-547632 95% 5mg $105 2021-12-16 Buy
Ambeed A867793 Cp-547632 95% 10mg $137 2021-12-16 Buy
Ambeed A867793 Cp-547632 95% 25mg $179 2021-12-16 Buy
Ambeed A867793 Cp-547632 95% 50mg $284 2021-12-16 Buy
American Custom Chemicals Corporation API0005167 CP-547632 95.00% 500MG $4966.5 2021-12-16 Buy
Biosynth Carbosynth FB102944 3-[(4-Bromo-2,6-difluorobenzyl)oxy]-5-[3-[4-(pyrrolidin-1-yl)butyl]ureido]isothiazole-4-carboxamide 1mg $60 2021-12-16 Buy
Biosynth Carbosynth FB102944 3-[(4-Bromo-2,6-difluorobenzyl)oxy]-5-[3-[4-(pyrrolidin-1-yl)butyl]ureido]isothiazole-4-carboxamide 2mg $100 2021-12-16 Buy
Biosynth Carbosynth FB102944 3-[(4-Bromo-2,6-difluorobenzyl)oxy]-5-[3-[4-(pyrrolidin-1-yl)butyl]ureido]isothiazole-4-carboxamide 5mg $220 2021-12-16 Buy
Biosynth Carbosynth FB102944 3-[(4-Bromo-2,6-difluorobenzyl)oxy]-5-[3-[4-(pyrrolidin-1-yl)butyl]ureido]isothiazole-4-carboxamide 10mg $400 2021-12-16 Buy
Biosynth Carbosynth FB102944 3-[(4-Bromo-2,6-difluorobenzyl)oxy]-5-[3-[4-(pyrrolidin-1-yl)butyl]ureido]isothiazole-4-carboxamide 25mg $750 2021-12-16 Buy
Cayman Chemical 21773 CP 547,632 ≥98% 500μg $57 2024-03-01 Buy
Cayman Chemical 21773 CP 547,632 ≥98% 1mg $107 2024-03-01 Buy
Cayman Chemical 21773 CP 547,632 ≥98% 5mg $437 2024-03-01 Buy
Chemenu CM280772 CP-547632 98% 100mg $1312 2021-12-16 Buy
ChemScene CS-0003189 CP-547632 >99.0% 5mg $95 2021-12-16 Buy

Properties

Boiling point :548.6±50.0 °C(Predicted)
Density :1.532
storage temp. :2-8°C
solubility :DMSO: 94 mM
form :A solid
pka :12.50±0.70(Predicted)
color :White to light yellow

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

CP 547,632 is an orally bioavailable and potent inhibitor of the receptor tyrosine kinases VEGF receptor 2 (VEGFR2) and basic fibroblast growth factor (bFGF) with IC50 values of 11 and 9 nM, respectively, in an enzyme assay. It is selective for VEGFR2 and bFGF over EGFR, PDGF receptor β (PDGFRβ), and related tyrosine kinases. CP 547,632 inhibits VEGFR2 autophosphorylation induced by VEGF in porcine aortic endothelial cells transfected with VEGFR2 (IC50 = 6 nM) and in a xenograft mouse model using NIH3T3/H-Ras cells (EC50 = 590 nM). It decreases angiogenesis induced by VEGF or bFGF and suppresses tumor growth in athymic mice.

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