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ChemicalBook >> CAS DataBase List >> CP466722

CP466722

CP466722 price.
  • $41 - $5250
  • Product name: CP466722
  • CAS: 1080622-86-1
  • MF: C17H15N7O2
  • MW: 349.35
  • EINECS:808-414-0
  • MDL Number:MFCD17392566
  • Synonyms:CP466722;1-(6,7-Dimethoxy-4-quinazolinyl)-3-(2-pyridinyl)-1H-1,2,4-triazol-5-amine;2-(6,7-dimethoxyquinazolin-4-yl)-5-(pyridin-2-yl)-2H-1,2,4-triazol-3-amine;1-(6,7-Dimethoxy-4-quinazolinyl)-3-(2-pyridinyl)-1H-1,2,4-triazol-5-amine CP 466722;2-(6,7-dimethoxyquinazolin-4-yl)-5-pyridin-2-yl-1,2,4-triazol-3-amine;CP-466722;CP466722;1-(6,7-Dimethoxyquinazolin-4-yl)-3-(pyridin-2-yl)-1H-1,2,4-triazol-5-amine;CP466722;CP 466722;CP-466722
34 prices
Selected condition:
Brand
  • aablocks
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Axon Medchem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Labseeker
  • Sigma-Aldrich
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 500mg
  • 1g
  • 5g
  • Manufactureraablocks
  • Product numberAA008TCB
  • Product descriptionCp-466722 ≥98%
  • Packaging25mg
  • Price$720
  • Updated2021-12-16
  • Buy
  • Manufactureraablocks
  • Product numberAA008TCB
  • Product descriptionCp-466722 ≥98%
  • Packaging5mg
  • Price$237
  • Updated2021-12-16
  • Buy
  • Manufactureraablocks
  • Product numberAA008TCB
  • Product descriptionCp-466722 ≥98%
  • Packaging1mg
  • Price$92
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA422631
  • Product descriptionCp-466722 98+%
  • Packaging100mg
  • Price$520
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001405
  • Product description1-(6,7-DIMETHOXY-4-QUINAZOLINYL)-3-(2-PYRIDINYL)-1H-1,2,4-TRIAZOL-5-AMINE 95.00%
  • Packaging25MG
  • Price$1458.19
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8625
  • Product descriptionCP-466722
  • Packaging50mg
  • Price$445
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8625
  • Product descriptionCP-466722
  • Packaging10mg
  • Price$162
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8625
  • Product descriptionCP-466722
  • Packaging5mg
  • Price$105
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1495
  • Product descriptionCP466722 99%
  • Packaging25mg
  • Price$374
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146164
  • Product descriptionCP466722 >99%
  • Packaging100mg
  • Price$615.4
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146164
  • Product descriptionCP466722 >99%
  • Packaging250mg
  • Price$1133.9
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146164
  • Product descriptionCP466722 >99%
  • Packaging1g
  • Price$2245.7
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD43368
  • Product description2-(6,7-dimethoxyquinazolin-4-yl)-5-(pyridin-2-yl)-2H-1,2,4-triazol-3-amine
  • Packaging25mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD43368
  • Product description2-(6,7-dimethoxyquinazolin-4-yl)-5-(pyridin-2-yl)-2H-1,2,4-triazol-3-amine
  • Packaging50mg
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD43368
  • Product description2-(6,7-dimethoxyquinazolin-4-yl)-5-(pyridin-2-yl)-2H-1,2,4-triazol-3-amine
  • Packaging100mg
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD43368
  • Product description2-(6,7-dimethoxyquinazolin-4-yl)-5-(pyridin-2-yl)-2H-1,2,4-triazol-3-amine
  • Packaging250mg
  • Price$500
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA008TCB Cp-466722 ≥98% 25mg $720 2021-12-16 Buy
aablocks AA008TCB Cp-466722 ≥98% 5mg $237 2021-12-16 Buy
aablocks AA008TCB Cp-466722 ≥98% 1mg $92 2021-12-16 Buy
Ambeed A422631 Cp-466722 98+% 100mg $520 2021-12-16 Buy
American Custom Chemicals Corporation KIN0001405 1-(6,7-DIMETHOXY-4-QUINAZOLINYL)-3-(2-PYRIDINYL)-1H-1,2,4-TRIAZOL-5-AMINE 95.00% 25MG $1458.19 2021-12-16 Buy
ApexBio Technology A8625 CP-466722 50mg $445 2021-12-16 Buy
ApexBio Technology A8625 CP-466722 10mg $162 2021-12-16 Buy
ApexBio Technology A8625 CP-466722 5mg $105 2021-12-16 Buy
Axon Medchem Axon1495 CP466722 99% 25mg $374 2021-12-16 Buy
Biorbyt Ltd orb146164 CP466722 >99% 100mg $615.4 2021-12-16 Buy
Biorbyt Ltd orb146164 CP466722 >99% 250mg $1133.9 2021-12-16 Buy
Biorbyt Ltd orb146164 CP466722 >99% 1g $2245.7 2021-12-16 Buy
Biosynth Carbosynth FD43368 2-(6,7-dimethoxyquinazolin-4-yl)-5-(pyridin-2-yl)-2H-1,2,4-triazol-3-amine 25mg $150 2021-12-16 Buy
Biosynth Carbosynth FD43368 2-(6,7-dimethoxyquinazolin-4-yl)-5-(pyridin-2-yl)-2H-1,2,4-triazol-3-amine 50mg $200 2021-12-16 Buy
Biosynth Carbosynth FD43368 2-(6,7-dimethoxyquinazolin-4-yl)-5-(pyridin-2-yl)-2H-1,2,4-triazol-3-amine 100mg $300 2021-12-16 Buy
Biosynth Carbosynth FD43368 2-(6,7-dimethoxyquinazolin-4-yl)-5-(pyridin-2-yl)-2H-1,2,4-triazol-3-amine 250mg $500 2021-12-16 Buy

Properties

Boiling point :642.3±65.0 °C(Predicted)
Density :1.48
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :DMSO: soluble0.5mg/mL, clear (warmed)
pka :0.00±0.19(Predicted)
form :powder
color :white to beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

CP 466,722 is an inhibitor of ataxia-telangiectasia mutated (ATM) kinase that inhibits ionizing radiation-induced ATM autophosphorylation and phosphorylation of the ATM targets SMC1, Chk2, and p53 in HeLa cells when used at a concentration of 10 μM. It is selective for ATM over PI3K and PIKK in HFF(hTERT) and A-T(hTERT) fibroblasts, respectively. CP 466,722 decreases cell survival in response to ionizing radiation in HeLa cells. It is also cytotoxic to MCF-7 and SKBr-3 breast cancer cells (IC50s = 16.92 and 12.78 μM, respectively).

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