Cyclosporin A
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- $10 - $2269.5
- Product name: Cyclosporin A
- CAS: 59865-13-3
- MF: C62H111N11O12
- MW: 1202.61
- EINECS:611-907-1
- MDL Number:MFCD00274558
- Synonyms:ol27-400 ;s7481f1 ;sandimmun ;Cyclospori;1,4,7,10,13,16,19,22,25,28,31-Undecaazacyclotritriacontane, cyclic peptide deriv.;30-Ethyl-33-(1-hydroxy-2-methyl-hex-4-enyl)-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-dipropan-2-yl-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone;Cipol N;Neoplanta
68 prices
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Brand
- Adipogen Life Sciences
- AK Scientific
- Alfa Aesar
- Apolloscientific
- Arctom
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 100
- 5mg
- 10mg
- 20mg
- 25mg
- 50mg
- c2163000
- 100mg
- 200mg
- 250mg
- 5x100mg
- 500mg
- 1ml
- 1g
- 4g
- 5g
- 10g
- 25g
- 100g
- y0000361
- 0
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0079-M100
- Product descriptionCyclosporin A ≥98%
- Packaging100mg
- Price$45
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0079-5100
- Product descriptionCyclosporin A ≥98%
- Packaging5x100mg
- Price$135
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberH890
- Product descriptionCyclosporin A
- Packaging5g
- Price$417
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ63191
- Product descriptionCyclosporin A, 99+%
- Packaging1g
- Price$227
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberJ63191
- Product descriptionCyclosporin A, 99+%
- Packaging5g
- Price$487
- Updated2024-03-01
- Buy
- ManufacturerApolloscientific
- Product numberBITP1533
- Product descriptionCyclosporineAfromBeauverianlyea
- Packaging1g
- Price$85
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBITP1533
- Product descriptionCyclosporineAfromBeauverianlyea
- Packaging4g
- Price$203
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS569732
- Product description(3S,6S,9R,12R,15S,18S,21S,24S,30S,33S)-30-Ethyl-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29, 97%
- Packaging25mg
- Price$10
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS569732
- Product description(3S,6S,9R,12R,15S,18S,21S,24S,30S,33S)-30-Ethyl-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29, 97%
- Packaging100mg
- Price$13
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS569732
- Product description(3S,6S,9R,12R,15S,18S,21S,24S,30S,33S)-30-Ethyl-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29, 97%
- Packaging250mg
- Price$18
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60180
- Product descriptionCyclosporin A ≥98%
- Packaging20mg
- Price$30
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS569732
- Product description(3S,6S,9R,12R,15S,18S,21S,24S,30S,33S)-30-Ethyl-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29, 97%
- Packaging1g
- Price$36
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberSY012000
- Product descriptionCyclosporin A ≥98%
- Packaging5g
- Price$115
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS569732
- Product description(3S,6S,9R,12R,15S,18S,21S,24S,30S,33S)-30-Ethyl-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29, 97%
- Packaging5g
- Price$140
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS569732
- Product description(3S,6S,9R,12R,15S,18S,21S,24S,30S,33S)-30-Ethyl-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29, 97%
- Packaging25g
- Price$346
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545830
- Product descriptionCyclosporine >98%
- Packaging100mg
- Price$154.7
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Adipogen Life Sciences | AG-CN2-0079-M100 | Cyclosporin A ≥98% | 100mg | $45 | 2021-12-16 | Buy |
Adipogen Life Sciences | AG-CN2-0079-5100 | Cyclosporin A ≥98% | 5x100mg | $135 | 2021-12-16 | Buy |
AK Scientific | H890 | Cyclosporin A | 5g | $417 | 2021-12-16 | Buy |
Alfa Aesar | J63191 | Cyclosporin A, 99+% | 1g | $227 | 2024-03-01 | Buy |
Alfa Aesar | J63191 | Cyclosporin A, 99+% | 5g | $487 | 2024-03-01 | Buy |
Apolloscientific | BITP1533 | CyclosporineAfromBeauverianlyea | 1g | $85 | 2021-12-16 | Buy |
Apolloscientific | BITP1533 | CyclosporineAfromBeauverianlyea | 4g | $203 | 2021-12-16 | Buy |
Arctom | AS569732 | (3S,6S,9R,12R,15S,18S,21S,24S,30S,33S)-30-Ethyl-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29, 97% | 25mg | $10 | 2021-12-16 | Buy |
Arctom | AS569732 | (3S,6S,9R,12R,15S,18S,21S,24S,30S,33S)-30-Ethyl-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29, 97% | 100mg | $13 | 2021-12-16 | Buy |
Arctom | AS569732 | (3S,6S,9R,12R,15S,18S,21S,24S,30S,33S)-30-Ethyl-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29, 97% | 250mg | $18 | 2021-12-16 | Buy |
Arctom | CFN60180 | Cyclosporin A ≥98% | 20mg | $30 | 2021-12-16 | Buy |
Arctom | AS569732 | (3S,6S,9R,12R,15S,18S,21S,24S,30S,33S)-30-Ethyl-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29, 97% | 1g | $36 | 2021-12-16 | Buy |
Arctom | SY012000 | Cyclosporin A ≥98% | 5g | $115 | 2021-12-16 | Buy |
Arctom | AS569732 | (3S,6S,9R,12R,15S,18S,21S,24S,30S,33S)-30-Ethyl-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29, 97% | 5g | $140 | 2021-12-16 | Buy |
Arctom | AS569732 | (3S,6S,9R,12R,15S,18S,21S,24S,30S,33S)-30-Ethyl-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29, 97% | 25g | $346 | 2021-12-16 | Buy |
Biorbyt Ltd | orb545830 | Cyclosporine >98% | 100mg | $154.7 | 2021-12-16 | Buy |
Properties
Melting point :148-151°C
Boiling point :838.63°C (rough estimate)
alpha :D20 -244° (c = 0.6 in chloroform); D20 -189° (c = 0.5 in methanol)
Density :0.9913 (rough estimate)
refractive index :1.6500 (estimate)
Flash point :87℃
storage temp. :-20°C
solubility :ethanol: 30 mg/mL
form :solid
pka :13.32±0.70(Predicted)
color :white
optical activity :-18922 (methanol)
Water Solubility :Soluble in dimethyl sulfoxide and ethanol. Insoluble in water.
Merck :14,2752
BRN :3647785
Stability :Stable for 3 years as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
InChIKey :PMATZTZNYRCHOR-CGLBZJNRSA-N
CAS DataBase Reference :59865-13-3(CAS DataBase Reference)
IARC :1 (Vol. 50, 100A) 2012
EPA Substance Registry System :Cyclosporin A (59865-13-3)
Boiling point :838.63°C (rough estimate)
alpha :D20 -244° (c = 0.6 in chloroform); D20 -189° (c = 0.5 in methanol)
Density :0.9913 (rough estimate)
refractive index :1.6500 (estimate)
Flash point :87℃
storage temp. :-20°C
solubility :ethanol: 30 mg/mL
form :solid
pka :13.32±0.70(Predicted)
color :white
optical activity :-18922 (methanol)
Water Solubility :Soluble in dimethyl sulfoxide and ethanol. Insoluble in water.
Merck :14,2752
BRN :3647785
Stability :Stable for 3 years as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
InChIKey :PMATZTZNYRCHOR-CGLBZJNRSA-N
CAS DataBase Reference :59865-13-3(CAS DataBase Reference)
IARC :1 (Vol. 50, 100A) 2012
EPA Substance Registry System :Cyclosporin A (59865-13-3)
Safety Information
Symbol(GHS): |
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Signal word: | Danger | |||||||||||||||||||||
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Description
Cyclosporin A is an immunosuppressant drug that binds cyclophilin D, inhibiting the phosphatase activity of calcineurin in T cells (IC50 = 5 nM). It blocks the transcription of genes involved in T cell activation by interfering with the calcineurin-driven nuclear import of the transcription factor NFAT. Because of its powerful immunosuppressant activity, cyclosporin A has long been used for the prevention of transplant rejection.More related product prices
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Suppliers and manufacturers
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