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ChemicalBook >> CAS DataBase List >> DDR1-IN-1

DDR1-IN-1

DDR1-IN-1 price.
  • $67 - $3580.2
  • Product name: DDR1-IN-1
  • CAS: 1449685-96-4
  • MF: C30H31F3N4O3
  • MW: 552.59
  • EINECS:
  • MDL Number:MFCD28144507
  • Synonyms:TL4-44;DDR-IN-1;DDR1-IN-1;N-[3-[(2,3-Dihydro-2-oxo-1H-indol-5-yl)oxy]-4-methylphenyl]-4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)benzamide;4-((4-ethylpiperazin-1-yl)methyl)-N-(4-methyl-3-((2-oxoindolin-5-yl)oxy)phenyl)-3-(trifluoromethyl)benzamide;CS-1427;DDR1 inhibitor 1;Benzamide, N-[3-[(2,3-dihydro-2-oxo-1H-indol-5-yl)oxy]-4-methylphenyl]-4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)-
21 prices
Selected condition:
Brand
  • ApexBio Technology
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
Package
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1000mg
  • 1g
  • ManufacturerApexBio Technology
  • Product numberB3383
  • Product descriptionDDR1-IN-1
  • Packaging5mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB3383
  • Product descriptionDDR1-IN-1
  • Packaging10mg
  • Price$239
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB3383
  • Product descriptionDDR1-IN-1
  • Packaging50mg
  • Price$1071
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB3383
  • Product descriptionDDR1-IN-1
  • Packaging100mg
  • Price$1733
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181232
  • Product descriptionDDR1-IN-1 >98%
  • Packaging100mg
  • Price$1030.2
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181232
  • Product descriptionDDR1-IN-1 >98%
  • Packaging250mg
  • Price$1949.9
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181232
  • Product descriptionDDR1-IN-1 >98%
  • Packaging1000mg
  • Price$3580.2
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBD165965
  • Product descriptionDDR1-IN-1 dihydrochloride
  • Packaging10mg
  • Price$145
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBD165965
  • Product descriptionDDR1-IN-1 dihydrochloride
  • Packaging50mg
  • Price$507.5
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM148946
  • Product description4-((4-ethylpiperazin-1-yl)methyl)-N-(4-methyl-3-((2-oxoindolin-5-yl)oxy)phenyl)-3-(trifluoromethyl)benzamide 95%+
  • Packaging100mg
  • Price$1450
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2808
  • Product descriptionDDR1-IN-1 98.20%
  • Packaging5mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2808
  • Product descriptionDDR1-IN-1 98.20%
  • Packaging10mg
  • Price$140
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2808
  • Product descriptionDDR1-IN-1 98.20%
  • Packaging50mg
  • Price$350
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2808
  • Product descriptionDDR1-IN-1 98.20%
  • Packaging100mg
  • Price$550
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003437
  • Product descriptionDDR1-IN-1 98+%
  • Packaging5mg
  • Price$67
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003437
  • Product descriptionDDR1-IN-1 98+%
  • Packaging10mg
  • Price$106
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ApexBio Technology B3383 DDR1-IN-1 5mg $150 2021-12-16 Buy
ApexBio Technology B3383 DDR1-IN-1 10mg $239 2021-12-16 Buy
ApexBio Technology B3383 DDR1-IN-1 50mg $1071 2021-12-16 Buy
ApexBio Technology B3383 DDR1-IN-1 100mg $1733 2021-12-16 Buy
Biorbyt Ltd orb181232 DDR1-IN-1 >98% 100mg $1030.2 2021-12-16 Buy
Biorbyt Ltd orb181232 DDR1-IN-1 >98% 250mg $1949.9 2021-12-16 Buy
Biorbyt Ltd orb181232 DDR1-IN-1 >98% 1000mg $3580.2 2021-12-16 Buy
Biosynth Carbosynth BD165965 DDR1-IN-1 dihydrochloride 10mg $145 2021-12-16 Buy
Biosynth Carbosynth BD165965 DDR1-IN-1 dihydrochloride 50mg $507.5 2021-12-16 Buy
Chemenu CM148946 4-((4-ethylpiperazin-1-yl)methyl)-N-(4-methyl-3-((2-oxoindolin-5-yl)oxy)phenyl)-3-(trifluoromethyl)benzamide 95%+ 100mg $1450 2021-12-16 Buy
ChemScene CS-2808 DDR1-IN-1 98.20% 5mg $90 2021-12-16 Buy
ChemScene CS-2808 DDR1-IN-1 98.20% 10mg $140 2021-12-16 Buy
ChemScene CS-2808 DDR1-IN-1 98.20% 50mg $350 2021-12-16 Buy
ChemScene CS-2808 DDR1-IN-1 98.20% 100mg $550 2021-12-16 Buy
Crysdot CD31003437 DDR1-IN-1 98+% 5mg $67 2021-12-16 Buy
Crysdot CD31003437 DDR1-IN-1 98+% 10mg $106 2021-12-16 Buy

Properties

storage temp. :Store at -20°C
solubility :DMSO : 100 mg/mL (180.97 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
form :Powder
color :Light yellow to yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

ChEBI: DDR1-IN-1 is a secondary carboxamide resulting from the formal condensation of the carboxy group of 4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)benzoic acid with the amino group of 5-(5-amino-2-methylphenoxy)-1,3-dihydro-2H-indol-2-one. It is a potent inhibitor of discoidin domain receptor tyrosine kinase 1 and 2 (DDR1/2) with IC50 = 105 nM and 413 nM, respectively. It has a role as an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor. It is a N-alkylpiperazine, a member of benzamides, a member of (trifluoromethyl)benzenes, a secondary carboxamide, an aromatic ether and a member of oxindoles.