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ChemicalBook >> CAS DataBase List >> DEMETHYLASTERRIQUINONE B1

DEMETHYLASTERRIQUINONE B1

DEMETHYLASTERRIQUINONE B1 price.
  • $81 - $786.45
  • Product name: DEMETHYLASTERRIQUINONE B1
  • CAS: 78860-34-1
  • MF: C32H30N2O4
  • MW: 506.59
  • EINECS:
  • MDL Number:MFCD06410990
  • Synonyms:2,5-DIHYDROXY-3-[7-(3-METHYL-BUT-2-ENYL)-1H-INDOL-3-YL]-6-[2-(1,1-DIMETHYL-ALLYL)-1H-INDOL-3-YL]-[1,4]BENZOQUINONE;2-[2-(1,1-DIMETHYL-2-PROPENYL)-1H-INDOL-3-YL]-3,6-DIHYDROXY-5-[7-(3-METHYL-2-BUTENYL)-1H-INDOL-3-YL]-2,5-CYCLOHEXADIENE-1,4-DIONE;2-[2-(1,1-DIMETHYLALLYL)-1H-INDOL-3-YL]-3,6-DIHYDROXY-5-[7-(3-METHYLBUT-2-ENYL)-1H-INDOL-3-YL][1,4]BENZOQUINONE;DAQ B1;DEMETHYLASTERRIQUINONE B1;DMAQ-B1;L-783,281;2-(2-(1,1-Dimethyl-2-propenyl)-1H-indol-3-yl)-3,6-dihydroxy-5-(7-(3-methyl-2-butenyl)-1H-indol-3-yl)-2,5-cyclohexadiene-
Price7 Properties Safety Information Description
7 prices
Selected condition：
Brand
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • Tocris
  • TRC
  • Usbiological
Package
  • 5
  • 1mg
  • 5MG
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberPRK0000052
  • Product descriptionDEMETHYLASTERRIQUINONE B1 95.00%
  • Packaging5MG
  • Price$786.45
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6869
  • Product descriptionDemethylasterriquinoneB1
  • Packaging5mg
  • Price$377
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number21026
  • Product descriptionDemethylasterriquinone B1 ≥98%
  • Packaging1mg
  • Price$81
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21026
  • Product descriptionDemethylasterriquinone B1 ≥98%
  • Packaging5mg
  • Price$302
  • Updated2024-03-01
  • Buy
  • ManufacturerTocris
  • Product number1819
  • Product descriptionDemethylasterriquinoneB1 ≥98%(HPLC)
  • Packaging5
  • Price$257
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberD230808
  • Product descriptionDemethylasterriquinoneB1
  • Packaging5mg
  • Price$235
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number255124
  • Product descriptionDemethylasterriquinone B1
  • Packaging5mg
  • Price$545
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation PRK0000052 DEMETHYLASTERRIQUINONE B1 95.00% 5MG $786.45 2021-12-16 Buy
ApexBio Technology B6869 DemethylasterriquinoneB1 5mg $377 2021-12-16 Buy
Cayman Chemical 21026 Demethylasterriquinone B1 ≥98% 1mg $81 2024-03-01 Buy
Cayman Chemical 21026 Demethylasterriquinone B1 ≥98% 5mg $302 2024-03-01 Buy
Tocris 1819 DemethylasterriquinoneB1 ≥98%(HPLC) 5 $257 2021-12-16 Buy
TRC D230808 DemethylasterriquinoneB1 5mg $235 2021-12-16 Buy
Usbiological 255124 Demethylasterriquinone B1 5mg $545 2021-12-16 Buy

Properties

Boiling point :780.2±60.0 °C(Predicted)
Density :1.335±0.06 g/cm3(Predicted)
storage temp. :Desiccate at -20°C
solubility :Soluble to 100 mM in DMSO
form :Powder
pka :2.82±0.50(Predicted)

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Demethylasterriquinone B1 is a cell-permeable asymmetrical bis-indolylquinone insulin mimic with anti-diabetic activity in animal models. Selectively stimulates insulin receptor (IR) tyrosine kinase activity (EC50 ~ 6 μM in CHOIR cells), while showing little effect towards IGF-1R, EGFR, or PDGFR. Demethylasterriquinone B1 also acts as an agonist for Trk A, Trk B and Trk C (the neurotrophin receptors TrkA, B, and C) in both cortical neurons and dorsal root ganglion neurons (~ 20 μM). DMAQ-B1 and insulin show differential effects on cellular gene expression profiles and DMAQ-B1 is a more selective agonist than insulin for the IR-mediated activation of PI-3 kinase/Akt pathway. Demethylasterriquinone B1 is an activator of insulin R.

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Suppliers and manufacturers

Fuxin Pharmaceutical
TargetMol Chemicals Inc.
Aladdin Scientific 3B Pharmachem (Wuhan) International Co.,Ltd. EMMX Biotechnology LLC Shanghai EFE Biological Technology Co., Ltd. Wuhan FengyaoTonghui Chemical Products Co., Ltd. BOC Sciences ChemeGen(Shanghai) Biotechnology Co.,Ltd. MedBioPharmaceutical Technology Inc